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Multi-slice target CT can distinctly display the shape of the edge and interior of the SPN,such as "sign of lobulation","rabbit-ear sign","vacuole sign","node-accumulating sign",which are useful to diagnose the lung cancer.

CT增强扫描病灶强化程度二者无显著区别,只能作为诊断参考,不能作为定性依据;CT薄层靶扫描能清晰反映病变边缘、内部结构,如分叶征、胸膜凹陷征、空泡征、小结节堆积征等,有助于肺癌的诊断。

In patients with a perilymphatic distribution, nodules are seen in relation to pleural surfaces, interlobular septa and the peribronchovascular interstitium.

在这种类型中,结节可以看到位于胸膜和小叶间隔、支气管血管旁间质

The main HRCT findings of the lung in nonsmokers were centrilobular emphysema in 12%, paraseptal emphysema in 8%, pleural micronodules in 32%, thickened interlobular septa in 12%, pulmonary bullae in 8% and air tapping in 8%.

非吸烟组HRCT表现:小叶中心型肺气肿(12%)、间隔旁型肺气肿(8%)、胸膜结节(32%)、小叶间隔线(12%)、肺大泡(8%)、空气潴留(8%)。

Results Stenosis or occlusion of bronchotracheal tree were observed in 5 patients with localized amyloidosis; Among 4 patients with systemic amyloidosis, 3 cases of pulmonary interstitial involvement, 4 cases of pleural thickening, 4 cases of pleural effusion, 3 cases of interventricular septum and ventricular walls thickening , 1 case of pericardial effusion were observed.

结果 5例局限性病变患者均有气管支气管树的狭窄或闭塞,其中2例分别合并左舌叶与右上叶阻塞性肺不张;4例全身性病变患者中肺间质病变3例,胸膜增厚4例,胸腔积液4例,室间隔与左心室肌增厚3例,心包积液1例。

Results The PET/CT imaging was performed for 62 patients including 7 cases with central bronchial carcinoma, and 55 cases with peripheral lung cancer. 59 cases with confirmed diagnosis, the diagnostic accuracy rate was 95.16%. Some abnormal enrichment can be seen by 18F-FDG PET/CT. The largest SUV is 1.0~22.3. Radioactivity intussuscept can be seen by 11C-MET and PET-CT, and SUV is 0.5~4.9. Vessel bunch is available by CT enhancement scan that can clear the borderline of lession. Sublobe,spicule sign,depressed pleura,and bronchia obstruction can be seen by HRCT.

结果 62例肺癌患者中,中央型肺癌7例,周围型肺癌55例,明确诊断59例,诊断率95.16%。18F-FDG PET/CT检查见病灶有不同程度放射性异常浓聚,最大SUV1.0~22.3; 11C-MET PET/CT检查的病灶均见不同程度放射性摄取,SUV0.5~4.9;CT增强扫描病灶边界清晰,明显强化,可见血管"集束征", HRCT检查见病灶有分叶、毛刺征、胸膜凹陷征及支气管阻断。

Results There were 27 patients with concrete lesion around lung and 18 patients in pleura.

结果45例患者,肺周围型病变27例,胸膜病变18例。

Results among 17 cases , malignant disease is 12 cases , benign disease is 5 cases ,in malignant disease adenocar-cinoma is 8 cases and squamous-cinoma is 2 cases ,in benign disease tuberculosis is 3 cases , inflammation node is 2 cases , the common CT signs included lobulation sign (14 cases),pleural tail sign 7 cases ,vessel convergence (8 cases ),and spiculation (14 cases),with inhomogeneous (13 cases).

结果:17例病变中恶性病例12例,良性病例5例,恶性病变中腺癌8例,鳞癌2例,转移癌2例,良性病变中结核3例,炎性结节2 例CT征象包括分叶征14例,胸膜凹陷征7例,血管集束征8例,毛刺征14例,密度不均匀者13例。

Moreover, in our experiments, we compare thequantification of other features, such as pleural indentation, lobulation sign et al, with thequalitative classification provided by radiologists. The results indicate that mostquantification of the features can obtain consistency higher than 87%.

针对毛刺征提出了一种基于边界法线-梯度正交性的毛刺量化方法,并与已有的毛刺量化方法进行了比较评估,分析表明该方法的量化结果与真实的毛刺水平具有更高的一致性;实验结果还表明分叶征、胸膜凹陷征等其它特征的量化分级大部分具有87%以上的正确率。

The CT features of peripheral lung cancer with diameter more than 3 cm, deep lobulation, frank cavitation, pleural indentation or mediastinal lymph node metastasis indicate higher degree of malignancy and proliferative activity of tumor cells.

周围型肺癌CT征象中,瘤体直径>3cm,或出现深分叶征、空洞、胸膜凹陷征、纵隔淋巴结转移者,具有相对更高的恶性程度,肿瘤细胞的增殖更为活跃。

Results The expression of p53 protein and PCNA was correlated with tumor size, deep lobulation, frank cavitation, pleural indentation and mediastinal lymph node metastasis, but not with spiculation.

结果 p53蛋白、PCNA表达与瘤体大小、深分叶征、空洞、胸膜凹陷征、纵隔淋巴结转移有关,与毛刺征无关。

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