胸腺细胞

Effect of Aconite Injection on the Spontaneous Incorporation of ~3H-TdR into Thymocytes in the Mice of Radiation Damage

目的 观察乌头注射液对辐射损伤小鼠胸腺细胞自发掺入3 H -TdR的作用。

Objective To investigate the effect of the dexamethasone on apoptosis of thymocyte in experimental allergic encephalomyelitis mice.

目的 探讨地塞米松对实验性变态反应性脑脊髓炎小鼠胸腺细胞凋亡的影响。

Five models were used to investigate the "Changdong"" s anti-tumor effect: mice S180 sarcoma solid model, mice liver cancer H22 solid model, mice Lewis lung cancer model, as well as human liver cancer QGY and colon cancer LOVO implanted in naked mice; mice liver cancer H22 was also used to evaluate the enhancive effect of "Changdong" when it was co-applied with other anti-tumor agent or with radiotherapy; The "Changdong"" s cytotoxic effect in vitro on such tumors as QGY, LOVO, lung cancer A549, breast cancer MCF-7, as well as mice leukemia P388 was observed through MTT method. And investigate the effect of "Changdong" on proliferation of spleen lymphocyte, on activity of NK cell and on synthesis of IL-2 in mice bearing Lewis lung cancer, respectively. With propidium iodide straining, cell aigptosis and cell circle were analyzed by flow cytometry. Result:"Changdong" has an evident tumor inhibitive effect on mice tumor model as well as human tumor implanted in naked mice with a quantity-effect relationship.

使用小鼠S180肉瘤、小鼠肝癌H22实体瘤和小鼠Lewis肺癌模型，以及人体肝癌QGY和人体肠癌LOVO裸鼠异种移植模型，进行"长动"的抗肿瘤药效学研究：用小鼠肝癌H22进行"长动"合并放疗和化疗的增效作用研究；用MTT法进行"长动"对肝癌QGY、肠癌LOVO、肺癌A549、乳腺癌MCF-7、小鼠白血病P388等10株人体和动物肿瘤细胞的体外细胞毒性作用研究；用淋巴细胞转化试验、小鼠NK细胞活性试验、小鼠胸腺细胞增殖法分别测定"长动"对荷Lewis肺癌小鼠的脾淋巴细胞增殖的影响、自然杀伤细胞活性的影响和对小鼠产生白介素-2(IL-2)的影响；用流式细胞仪PI单染色法进行"长动"对人体肝癌QGY细胞的体外诱导凋亡作用和对肿瘤细胞周期的影响的研究。

AIM: To study the effect of ERK inhibition on the mitochondrial potential change in dexamethasone-induced thymocyte apoptosis.

目的：研究阻断ERK途径对地塞米松诱导的胸腺细胞凋亡中线粒体膜电势的影响。

Objective To investigate the preventive effect of complete Freund's adjuvant induced thymocyte apoptosis on NOD mice with type 1 diabetes.

目的 探讨完全弗氏佐剂诱导胸腺细胞凋亡对NOD鼠1型糖尿病的预防作用。

Objective:To observe the effect of antithymocyte globulin on early steroid-resistant rejcctions after kidney transplantation.

目的：观察抗胸腺细胞球蛋白治疗肾移植术后早期耐激素排斥反应的效果。

Antithymocyte globulin is employed for the treatment and prevention of acute organ rejection after transplantation.

抗胸腺细胞球蛋白被用来治疗和预防器官移植后的急性排斥反应。

In order to study the role of cellular interaction in hemopoiesis, syngeneic marrow nucleated cells and thymocytes suspensions obtained from the same mouse were transfused i.

小鼠胸腺细胞对多向性造血干细胞的分化也有明显的影响；本实验表明首先出现红系分化的增强，然后再出现粒系分化的增强。

Methods: Investigate if cyclophosphamide produces the immunosuppression by the induction of apoptotic cell death in thymus .

以大鼠胸腺为对象，采用细胞凋亡的原位特异性染色及DNA凝胶电泳的方法，观察不同剂量、不同时间环磷酰胺处理后胸腺细胞的凋亡现象。

Methods : We gave 0, 1, 2, 3, 4 times low dose total-body irradiation to control group (No. 1 group) and experiment group (No. 2, 3,4,5 group) respectively with γ irradiation .Each dose is 0. 1GY and dose rate is 1.28 cGY/min. The interval of each irradiation is 48 hours . Six hours after every group finished their own total dose , we kill the rats and get their thyme .

采用γ射线分别对对照组(1组)和实验组(2、3、4、5组)给予0、1、2、3、4次低剂量全身照射，单次剂量0.1GY，剂量率为1.28cGY／min，每次照射间隔时间48小时，各组在完成照射总剂量后6小时处死取胸腺，采用双参数直接免疫荧光流式细胞术，检测大鼠低剂量全身照射后胸腺细胞CD4、CD8、CD3~+T细胞的表达情况以及CD4／CD8的变化。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。