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Apoptosis of lymphocytes in bone marrow, spleen, thymus and bursa was detected by light microscope, electron microscope and terminal- deoxynucleotidyl transferase UIP nick end labeling. The results showed ALV-J could induce incoordinate apoptosis of lymphocytes in thymus, bursa and spleen, which was mainly found in early time. And the apoptosis was much more obvious in thymus than in other immune organs.

以电镜观察和HE染色、原位末端标记染色光镜观察对ALV-J感染和混合感染鸡的骨髓、脾脏、胸腺、法氏囊等免疫器官中淋巴细胞的凋亡进行了形态学研究,首次发现ALV-J可诱导胸腺、法氏囊和脾脏中不同程度的淋巴细胞凋亡,凋亡主要见于早期,ALV-J与REV混合感染时淋巴细胞凋亡尤为显著,以胸腺中最为明显。

The result indicate that the DPV DNA can be firstly detected 2 hours after inoculability from brain,liver,spleen,bursa of fabricius,thymus.

结果表明,接种2小时后即能够从脑、肝、脾、法氏囊、胸腺中检出DPV DNA.12小时,即可从心脏、肝脏、脾脏、肺脏、肾脏、十二指肠、直肠、法氏囊、胸腺、胰腺、脑组织、胸肌、食道、腺胃、血液、舌头、口腔分泌物、皮肤、骨髓和粪便等20种组织器官中检测到DPV的DNA。检出时间最早和检出率最高的组织器官为肝脏和脑组织。

For the immune system of a newborn mammal to develop properly, the presence of the thymus gland is essentially.

翻译参考:对于一个新生儿的免疫系统的正常地发展,胸腺的存在是必要的。

The critical role of the thymus in the immune system is becoming increasingly well understood.

在免疫的系统里的胸腺的关键的角色正变得被越来越清楚地理解。

Objective:in order to compare the curative effects of using lamirudine and thymosin together with using thymosin only to the paients of chronic hepatitis b.methods:we had chosen 27 medical cases of chronic hepatitis b,which were divided into two groups:15 cases asone group,and 12 cases as the other group.let group a take 100 mglamirudine orally,qd,with half a year as a period of treatment.at the same time givethe patients injections of 100 mg thymosin,qd,for a month.to group b was only takenlamirudine.alt,tbil,the indicators of the virosis of hepatitis b (hbsag,hbeag,hbv-dna)were observed as quatos.results: at the end of the treatment, the rates that groupa and group b made hbsag transform into negative were respectively 26.67% and 16.67%(p>0.05);hbeag:33.33%,8.33%;hbv-dna:53.33%,33.33%(p>0.05).conclusion:combining thymic peptide with 3tc to treat chronic type b hepatitis, thymic peptide will not only promote b-cell to mature and transformation, but also to keep the subpopulation of t-cell in immune system in balance, which can enhance the reaction of matured t-cell to the antigen or other stimulus.

目的:比较拉米夫定(3tc)与胸腺肽联用和单用拉米夫定治疗慢性乙型肝炎的疗效。方法:选择慢性乙型肝炎患者27例,分为联合组15例和拉米夫定组12例;联合组用拉米夫定100 mg,口服,qd,疗程半年,合并用胸腺肽100 mg,静滴,qd,疗程1个月。拉米夫定组单用拉米夫定。以谷丙转氨酶、血清胆红素、乙肝病毒标志物(hbsag,hbeag,hbv-dna)为观察指标,比较不同治疗方案对指标的影响。结果:治疗结束时联合组与拉米夫定组对慢性乙肝患者血清hbsag阴转率分别是26.67%和16.67%(p>0.05);hbeag阴转率分别是33.33%和8.33%(p>0.05);hbv-dna阴转率分别是53.33%和33.33%(p>0.05)。结论:胸腺肽联合3tc治疗慢乙肝,胸腺肽具有促进t淋巴细胞的成熟和转化,并维持免疫系统各t淋巴细胞亚群间的平衡作用,能增强成熟t淋巴细胞对抗原或其他刺激的反应。

Among them VLP- 1 100 mg / kg d acts best, the transition rate of achroacyte reach 65.5013%, each VLP -1 dosage has apparent effects to the live weight gain of normal rats' immunization organic, VLP-1 50 mg / kg d and 100 mg / kg d have sorely significantly live weight gain function to thymus and milt, when VLP-1 is 25 mg / kg d, the thymus weight increase sorely significantly while milt increase not too much.

各VLP一1剂量对正常小鼠免疫器官的增重均有明显作用,其中VLP一1在50 mg/kg.d、100 mg/kg·d剂量下对胸腺、脾脏有极显著地增重作用,在25mg/kg 。d 剂量下极显著地增加胸腺重量,而对脾脏增重无影响;粗多糖仅在100mg/kg·d 剂量下对脾脏增重有明显作用外,其余各剂量对正常小鼠胸腺、脾脏增重无影响。

There were 35% patients with thymomas, and the thymomas were excised.

有35 %的病人合并有胸腺瘤、胸腺增生,行胸腺切除术。

We compared the difference of gene expression between thymus in one-and ten-month old Balb/c micee using DDRT-PCR. It was found that there would be a significant difference of gene expressions in murine thymuses.

我们采用差异显示反转录PCR技术对1月和10月龄Balb/c小鼠胸腺mRNA的差异表达情况进行了分析,共获得月龄差异表达的cDNA片段108条(其中90条源于1月龄小鼠胸腺中,而有18条源于10月龄小鼠胸腺中)。

Methods The genomic DNA was extracted from murine thymocytes and splenocytes for PCR amplification of the target fragments.

推测其中的初始T细胞的数目,评价胸腺功能,从而为胸腺功能研究及胸腺研究模型的建立提供研究依据和方法。

Furthermore, neurologists and physicians require a better understanding of freeduancom the surgical aspects of the thymus.

而且,神经病学家和内科医生需要更好的理解freeduancom 胸腺的外科的方面。

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这一模式非常关注商人的网络信用基础。

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