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Two kinds of water-soluble biomimetic chitosan derivatives with a phosphoramide linkage between glucosamine and choline were prepared through Atherton-Todd reaction under the mild conditions, including zwitterionic phosphorylcholine bound chitosan and acetyl-phosphorylcholine bound chitosan with positive charge. The interaction between chitosan derivatives and calf thymus DNA were inversigated by UV alsorption spectra and circular dichroism spectra.

采用Antherton-Todd反应制备了两种水溶性的磷酰化壳聚糖仿生衍生物:两性的N-磷酸胆碱磷酰化壳聚糖和带正电荷的N-乙基磷酸胆碱磷酰化壳聚糖,并用紫外吸收光谱和圆二色光谱研究了两种胆碱磷酰化壳聚糖衍生物与小牛胸腺DNA的相互作用。

Results Being compared with the normal group, the PDS mice showed a slower growth of body weight and a lower body temperature, a shorter mean retention time of chyme in digestive tract and faster gastric emptying velocity, a lower gastrin content, and a higher motilin content. Also splenic and thymus indexes were found to follow a downtrend in the PDS mice. Three dosages of SJZD showed a restoration effect on the above all indexes, and the high dosage was the most effective one, especially.

结果脾虚证小鼠体重增长缓慢,体温降低、消化道内食糜平均滞留时间缩短、胃排空加快、胃泌素的量降低、胃动素的量升高,脾脏和胸腺指数降低。3种剂量的四君子汤对脾虚证小鼠以上各指标的变化均有明显的矫正作用,以高剂量效果最佳。

The results showed that early feed restriction treatments significantly reduced the total incidence and total mortality of broiler. This was correlated with the accelerated development of spleen, Fabricius bursa, thymus and the increased humoral immune function of fed restricted broiler.

试验结果显示,早期限饲显著降低了肉鸡的发病率和死亡率,这可能与早期限饲促进了肉鸡的脾脏、法氏囊、胸腺等免疫器官的发育,提高了机体的抗体滴度有关。

In accordance with the fact that 5-brom-odeoxyuridinecan incorporate period-ically into the nuclear DNA to substitutethe thymidine in DNA,we devoloped a newbasic fuchsin staining method in which weused BrdU as a chromosomal marker in in situnick translation of chromosomes.

根据5—溴脱氧尿嘧啶核苷可周期性替代DNA链中的胸腺嘧啶核苷而显示不同细胞周期染色体的特性,我们用BrdU作为染色体的标记,首次建立了一种硷性复红染色的染色体原位切口移位的新方法。

The test groups were drenched orally with different dosages of compound Radix scutellariae granules. After being drenched orally for ten days, their thymus-index and spleen-nidex, immune globulins of IgA, IgG, IgM and alexins of C3, C4 of serum were defermined, and experiments in vivo were done. The mice-spleen's lymphocytes which were cultured in vivo were added with different concentrations of compound Radix scutellariae granules. The lymphocytes translation stimulate indexes were measured. The ability of licking up neutral red of the peritoneal macrophages cultured in vivo was measured in the groups.

应用复方黄芩颗粒给小鼠灌胃10d后,分别测定对照组与实验组胸腺指数、脾脏指数和血清中的免疫球蛋白IgA、IgG、IgM和补体C3、C4;并且进行体外实验,用不同浓度的复方黄芩颗粒剂对小鼠脾脏淋巴细胞进行体外培养,测定淋巴细胞转移刺激指数;在体外培养测定细胞吞噬中性红的能力。

These data indicated the presen c e of monoamines neurotransmitter in rat thymus and implicated that 5-HT might be involved in the regulation of blood circulation of thymus and the functions of matural T cells.

大鼠胸腺内确实存在单胺类神经递质,推测5-HT可能参与成熟T细胞的功能调节和局部血循环的调节,从而控制T细胞的迁移。

By incorporation of tritiated thymidine or 5-bromodeoxyuridine and using them as the markers, we found that the basal cells, Clara cells and type II alveolar epithelial cells in the pulmonary tissues may in some way behave like stem cells and can eventually differentiate into respiratory tract epithelium.

通过应用cells in induced group cultured for 2 weeks 标记的胸腺嘧啶(3H-TdR)或5-溴脱氧尿核苷的渗入进行标记,发现肺组织的基底细胞、Clara 细胞和肺泡II型上皮细胞可能具有干细胞特征,能最终分化形成气道上皮。

By incorporation of tritiated thymidine or 5-bromodeoxyuridine and using them as the markers, we found that the basal cells, Clara cells and type Ⅱ alveolar epithelial cells in the pulmonary tissues may in some way behave like stem cells and can eventually differentiate into respiratory tract epithelium.

通过应用cells in induced group cultured for 2 weeks von kossa staining)标记的胸腺嘧啶(3H-TdR或5-溴脱氧尿核苷的渗入进行标记,发现肺组织的基底细胞、clara细胞和肺泡Ⅱ型上皮细胞可能具有干细胞特征,能最终分化形成气道上皮。

What did the addition of thymidine to the

在你的实验中加入放射性标记的胸腺嘧啶的作用是什么?

As a result,1A360 probe did hybridize strongly to Tester DNA sample,but weakly to Driver DNA.Thus,our two rounds of RDA are proved to be specific andeffective.Because of not hybridizing to the liver tissue DNA of rat and the thymicDNA of bull,so the probe is species-specific and gained from human chromosome.

该探针不能与鼠肝组织和小牛胸腺组织DNA杂交,说明它来源于人源染色体并有种属的特异性。1A360基因片段探针还与多种胃癌细胞系,胃癌组织DNA有较强的杂交信号,与其它肿瘤DNA有强弱不等的杂交信号。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

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