胸腺嘧啶

The one electron oxidative splitting reaction mechanism between 9,10-anthraquinone-2-sulfonate and cyclobutane dimethylthymine dimer was acquired.

研究了蒽醌-2-磺酸盐与环丁烷型二甲基胸腺嘧啶二聚体发生的单电子氧化裂解反应机理。

In order to mimic this repair process of apoenzyme, we synthesized two model compounds, in which tryptophan and/or tyrosine was covalently linked to cyclobutane thymine dimer, and measured the splitting quantum yield of dimer under 295 nm light. By investigating the photosensitized splitting properties of the dimer, some new insights into the intramolecular electron-transfer process were gained.

为了模拟酶蛋白的这一修复过程，合成了色氨酸和/或酪氨酸与胸腺嘧啶二聚体共价连接的化合物，作为酶-底物复合物的模型，研究了它们在295 nm光照射下氨基酸残基光敏化二聚体裂解的性质，测定了二聚体裂解量子产率，获得一些新的结果并对其进行了分析。

Aim To investigate the production and removal of cyclobutane pyrimidine diners after UVB irradiation and the effect of baikal skullcap root, szechwan lovge rhizome and epigallocatechingallate on the irradiation damage in HaCaT cells, and finally, to clarify the probable regulatory mechanisms. Methods HaCaT cells were cultured in RMPI-1640 medium with 10% fetal bovine serum. The time and dosage of UVB irradiation were conducted according to the experimental design. Tested medicines were added into the medium before or after UVB irradiation.

目的 观察中波紫外线辐射后HaCaT细胞光产物胸腺嘧啶二聚体(cyclobutanepyrimidine dimers， CPDs)的生成和清除情况及3种中药活性成分：黄芩(baikal skullcap root， BSR)、川芎(szechwan lovge rhizome， SLR)和表没食子儿茶素没食子酸酯[-epigallocatechin-3-gallate， EGCG]对该过程的干预情况并探讨上述药物对相关调控分子的作用机制。

Resembles thymine, but easily interconverts to tautomeric form that pairs with guanine.

与胸腺嘧啶相似，但很容易转换成与鸟嘌呤配对的互变异构形式。

METHODS Upon the model of cultured rat FBs, C a2+ influx stimulated with Ang Ⅱ,CaN signaling pathway was blocked with c yclosporine Aand Ca2+ channel with verapamil, detecting the ac tivities of FBs CaN, mitogen activated protein kinase and protein kinas e C,［3H］-leucine(［3H］-Leu) and ［3H］-thymidine(［3H］-Td R) incorporation as the target to evaluate FBs proliferation.

方法以培养的FBs为模型，用Ang Ⅱ剌激FBs外Ca2+入流，环孢素A阻断CaN信号通路，维拉帕米阻断FBs钙通道，检测FBs CaN、丝裂素活化蛋白激酶、蛋白激酶C活性，用［3H］-亮氨酸及［3H］-胸腺嘧啶参入量作为反应FB s增殖的指标。

By incorporation of tritiated thymidine or 5-bromodeoxyuridine and using them as the markers, we found that the basal cells, Clara cells and type II alveolar epithelial cells in the pulmonary tissues may in some way behave like stem cells and can eventually differentiate into respiratory tract epithelium.

通过应用cells in induced group cultured for 2 weeks 标记的胸腺嘧啶(3H-TdR)或5-溴脱氧尿核苷的渗入进行标记，发现肺组织的基底细胞、Clara 细胞和肺泡II型上皮细胞可能具有干细胞特征，能最终分化形成气道上皮。

By incorporation of tritiated thymidine or 5-bromodeoxyuridine and using them as the markers, we found that the basal cells, Clara cells and type Ⅱ alveolar epithelial cells in the pulmonary tissues may in some way behave like stem cells and can eventually differentiate into respiratory tract epithelium.

通过应用cells in induced group cultured for 2 weeks von kossa staining）标记的胸腺嘧啶(3H-TdR或5-溴脱氧尿核苷的渗入进行标记，发现肺组织的基底细胞、clara细胞和肺泡Ⅱ型上皮细胞可能具有干细胞特征，能最终分化形成气道上皮。

What did the addition of thymidine to the

在你的实验中加入放射性标记的胸腺嘧啶的作用是什么？

In vivo gene therapy of ovarian cancer by adenovirus－mediated thymidine kinase gene transduction and ganciclovir administration.

羟甲基无环鸟苷对携有单纯疱疹病毒胸腺嘧啶核苷激酶基因人卵巢癌裸鼠皮下移植瘤生长的抑制作用。

Objective:To study the relationships between the expression of thymidine phosphorylase,the density of microvesselsof the tumor,the clinical and pathological features and tumor-free survival rate in endometrial carcinoma.

目的：探讨胸腺嘧啶核苷磷酸化酶与子宫内膜癌的临床病理特征、无瘤生存率、微血管密度的关系。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。