胸腺

ConclusionThe first experiment Immunetolerance in mice sciatic nerve allograft by intrathymic injection of allogene : the specific immune tolerance can be induced in the sciatic nerve allograft by intrathymus injection of MHC allogene.

研究结论：第一部分：小鼠胸腺内注射异基因抗原在同种异体坐骨神经移植免疫耐受中的作用胸腺内注射异基因MHC抗原可诱导异体坐骨神经移植的特异性免疫耐受。

The level of PGE was assayed by spectrophotometer; Meanwhile, 3H-TdR incorporation method was used to detect ConA- and LPS- induced splenocytes proliferation and the production of interleukin-1 and IL-2. The content of antibodies to CII was determined by ELISA method. Pathological examination of articulus tissue was observed by Hematoxylin-eosin stain.

检测小鼠足爪肿胀度并对炎症进行评分；测定胸腺指数和脾脏指数；~3H-TdR参入法检测胸腺、脾淋巴细胞增殖反应；~3H-TdR参入法测定白细胞介素-1(interleukin-1，IL-1)和IL-2水平；ELISA法测定小鼠血清中抗CⅡ抗体含量；分光光度法检测足爪局部产生的前列腺素水平；HE染色法对关节组织作病理检查。

The results of this study indicated that there were changes on the distribution of T-lymphocyte subsets in patients with asthenia gravis.

MG患者存在有明显的T细胞亚群的改变，符合自身免疫性疾病的特点：胸腺切除手术近期对患者周围血中各淋巴亚群无明显影响；胸腺切除围手术期使用TP-5治疗对其发挥免疫调节作用的主要机理之一。

Different extracts prepared from Caesalpinia Sappan L were lavaged to the mice in order to count thymus index by taking out their thymus, to calculate the proliferation capacity of spleen T cells by using MTT method, to measure the INF-γcontent generated by T cell culture supernatant by using double-antibody sandwich ELISA method.

通过制备苏木不同提取物分别给予灌胃小鼠，取小鼠胸腺称重计算胸腺指数；采用MTT法测定小鼠脾T细胞的增殖能力；用双抗体夹心ELISA法测定T细胞培养上清中产生INF-γ的含量。

Result: In the 3 categories and 10 exemples of congenital malformation fetus, The morphologic observation and histological observation of thymus in syndactylia, ectrodactylia and Siamese fetus was no obvious abnormity, but the morphologic observation and his-tological observation of thymus in anencephaly fetus appeared Obvious abnormity.

结果：三类、10例先天畸形胎儿中，并、缺指畸形和联体畸形胎儿胸腺的大体形态和组织学观察无明显异常，无脑畸形胎儿胸腺的大体形态和组织学观察出现明显异常。

Compared with control,①the mean tumor weight of H22 of SXKA Granules three dose groups were decreased significantly(P.01,P.05),and the mean inhibition rates of SXKA Granules 20、10 g/kg dose groups were above 30%;②the mean tumor weight of S180 of SXKA Granules three dose groups were decreased significantly(P.01),and the mean inhibition rates of SXKA Granules 20、10 g/kg dose groups were above 32%;③the mean tumor weight of EAC of SXKA Granules three dose groups were decreased significantly ( P.01, P.05),and the mean inhibition rates of SXKA Granules 20 g/kg dose groups were above 38%;④the mean tumor weight of Lewis carcinoma of SXKA Granules three dose groups were decreased significantly(P.01, P.05),and the mean inhibition rates of SXKA Granules 20、10、5 g/kg dose groups were above 36%;⑤the mean tumor weight of W256 of SXKA Granules three dose groups were decreased significantly ( P.01, P.05),and the mean inhibition rates of SXKA Granules 20、10 g/kg dose groups were above 32%;⑵Compared with control,SXKA Granules 20、10 g/kg dose groups had extended the survial time of the P388-bearing mice respectively(P.01),and the mean prolong rates of SXKA Granules 20、10 g/kg dose groups were above 50%;⑶Compared with S180-bearing group, SXKA Granules 20、10 g/kg dose groups could increase the weight of thymus and spleen, Spleen index and thymus index were increased, SXKA Granules 5 g/kg dose group could increase thymus index(P.05);⑷As Compared with control group, SXKA Granules 20、10 g/kg dose groups could improve mouse serum half hemolysis value depressed by transplanted tumor dramatically(P.01), which revealed the SXKA granules could improve the mouse humoral immunity system;⑸SXKA Granules 20 g/kg dose group could increase of englobe indexαon S180-bearing mice remarkably(P.01), which indicated the SXKA Granules could improve their cellular immunity system.

对荷W256大鼠，生兴克癌冲剂20、10、5 g / kg三组的平均瘤重明显低于对照组(P.01，P.05)，生兴克癌冲剂20、10 g / kg组的平均肿瘤抑制率均大于32 %；⑵与空白对照组相比，生兴克癌冲剂20、10 g/ kg能显著地延长移植小鼠白血病P388小鼠的存活天数(P.01)，生兴克癌冲剂20、10 g/ kg对荷白血病P388小鼠生命延长率均在50%以上；⑶与S180荷瘤组相比，生兴克癌冲剂对荷瘤鼠的免疫器官重量、胸腺指数和脾指数有一定的提高趋势，其中生兴克癌冲剂5 g / kg组对荷瘤小鼠的胸腺指数有一定的提高作用(P.05)；⑷与S180荷瘤组相比，生兴克癌冲剂20、10 g /kg组可提高由荷瘤引起的小鼠血清半数溶血素值的降低(P.01)，表明其可提高荷瘤小鼠体液免疫功能；⑸与对照组相比，生兴克癌冲剂20 g /kg组可提高荷S180肉瘤小鼠的免疫吞噬系数α值(P.01)，表明其可提高荷瘤小鼠细胞免疫功能。

The BLSAg appeared in the spleen,the tonsillia cecalia and thymus,the bursa Fabricius,the red marrow and Harderian's gland at the lst week,7th week and 19th week post inoculation.

BLSAg阳性淋巴细胞早期主要分布在胸腺和外周免疫器官的T 淋巴细胞区，第 7周在胸腺、法氏囊和外周免疫器官的T、B淋巴细胞区。

Since hyperplastic changes were seen in 35% of MuSK-negatie patients, the thymus could be inoled in some of these cases.

然而在35%的MuSK抗体阴性的病人中可见明显胸腺增生，提示胸腺在此类病人的致病机制中有一定的作用。

The changes of muscle protein content and pH values were observed. Results Thymus and spleen coefficients in high and low dosage group were 9.1±2.3, 6.3±1.1, respectively, and those of in the controll were 6.5±1.6, 3.4±0.5.The contents of muscle protein (g/100 g) in high, medium, and low dose groups were 24.68±0.55, 22.48±0.54, 21.22±1.25, respectively, lower than that of the control (31.83±2.36, P.05). Paramorphia of lymphocyte in high dose ciprofloxacin treated group was observed.

结果 对照组胸腺和脾脏系数分别为(9.1±2.3)，(6.3±1.1)mg/g，高剂量组胸腺和脾脏系数分别为(6.5±1.6)，(3.4±0.5)mg/g，与对照组比较，差异均有统计学意义（P.05或P.01）；而中、低剂量组的脾脏指数与对照组比较，差异均有统计学意义(P.05)；环丙沙星各剂量组与对照组比较，肌肉pH值变化不明显；环丙沙星高、中、低剂量肌肉蛋白质含量分别为(24.68±0.55)，(22.48±0.54)，(21.22±1.25)g/100 g，与对照组(31.83±2.36)g/100 g比较明显下降(P.05)；与对照组比较，高剂量组脾淋巴细胞形态异常。

MethodsThe transplanted tumor model of the mouse S180 sarcoma was established.Fifty mice were randomly divided into five groups,the control group,the CTX group,the Gecko group.They were treated respectively with oral administration of saline,and intraperitoneal injection of CTX 100 mg/kg only one time,oral administration of Gecko in doses of 13.5,9,4.5 g/kg,one time a day.After 14 days,the anti-tumor activity was evaluated by tumor tissue weighing. The impact on immune organ was detected by accounting thymus index, spleen index and the number of peritoneal macrophage which phagocytose chicken red blood cells.The protein express of vascular endothelin growth factor and basic fibroblast growth factor were detected by SABC immunohistochemistry.

方法建立移植瘤小鼠S180肉瘤模型，将50只雌鼠随机分为对照组、环磷酰胺组、壁虎高组、中组、低组共5组，分别给于生理盐水灌胃1次/d，CTX（100 mg/kg）腹腔注射1次，壁虎高、中、低组（13.5，9，4.5 g/kg），每天灌胃1次。14 d后，称取荷瘤小鼠瘤重、胸腺重、脾脏重，计算抑瘤率、胸腺指数、脾脏指数，观察腹腔巨噬细胞吞噬鸡血红细胞实验指标；用SABC免疫组化法检测血管内皮生长因子、碱性成纤维细胞生长因子的蛋白表达，TUNEL方法检测细胞凋亡率。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。