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The EAE rats were induced by injecting subcutaneously an emulsion of GPSCH and CFA. In addition, each rat received an intracutaneous injection of pertussis. Albumin in serum and CSF samples was examined on the days of 4,6,8,10,12,14,16,18 and 20 p.i.. The integrity of BBB was assessed by caculating CSF to serum albumin quotient. At the same time the brains, spinal cords, thymus and inguinal lymph nodes were removed for paraffin sections cutting. These sections were used for HE staining and ICAM-1 semiquantitative immunohistochemical staining. The results showed as follows:1. None of EAE rats on days 4,6 and 8 p.i. showed clinical signs whichbecame apparent on day 10 p.i.(2.33±0.76; n=6). On days 12 and 14 p.i.

检测p.i。第4天、6天、8天、10天、12天、14天、16天、18天、20天血清和CSF中ALB含量,其CSF/S ALB比值作为评价BBB损害的指标;同时段取动物脑、脊髓、胸腺和腹股沟淋巴结制成石蜡切片行HE染色和ICAM-1半定量免疫组化分析,结果显示如下: 1、EAE大鼠p.i.4-8天无任何临床表现;p.i.10天症状开始明显,症状评分为2.33±0.76(n=6);p.i.12-14天为发病高峰期,症状评分为3.75±0.54(n=12),病情由最初的活动减少,体重减轻逐渐发展为肢体无力、瘫痪,共济失调,甚至濒死状态;p.i.16天大部分动物症状开始缓解,评分为2.08±0.66(n=6);p.i.20天疾病症状完全消失。

In the whole rats, the following tissues or organs were extracted and fixed in the most appropriated fixator (Bouin liquid or Formalin at 10%) then included in paraffin blocks : all the organs showing significant macroscopic lesions, encephalon (brain hemisphere, cerebellum and annular protuberance), spinal cord, sciatic nerve, salivary glands, esophagus, stomach, duodenum, jejunum, ileon, caecum and colon, rectum, liver, spleen, bone marrow, lymph node close to and at distance, thymus, heart, aorta, trachea, lungs, thyroid/parathyroid, surrenals, pancreas, hypophysis, kidney, bladder, gonad, uterus, mammary glands, epididymis, prostate, eyes, lachrymal glands, bones, skin, thigh muscle and implantation sites (2 per animal).

从整体大鼠内,下列组织或器官提取后用最适宜的固化剂( Bouin 液或10%的甲醛溶液)进行固定,然后包入石蜡块内:所有显示有明显肉眼可见损害的器官、脑髓、脊髓、坐骨神经、唾液腺、食道、胃、十二指肠、空肠、回肠、盲肠、大肠、直肠、肝脏、脾、骨髓、近端和远端淋巴结、胸腺、心脏、主动脉、气管、肺、甲状腺/甲状旁腺、肾上腺、胰腺、垂体、肾、膀胱、性腺、子宫、乳腺、附睾、前列腺、眼睛、泪腺、骨骼、皮肤、股肌以及假体植入部位(每只动物2处)。

ResultsComparing with gonadectomy Shenyangxu model group, Wenyangyishen Capsules can improve upset excitability of male rat of gonadectomy penis Home News for Overseas Service Department , shorten erection incubation period; The rat increasing gonadectomy male sex attaches weight modulus of sexual organ; Can urge the hypophysis , adrenal gland weight modulus to increase by, weight adjusting the thymus gland , spleen; Elevate rat serum testosterone、Cortisol contents obviously; Be caused by messenger Cortisol the various Shenyangxu model small rat symptom gets laxation disappear even.

结果 与去势肾阳虚模型组比较,温阳益肾胶囊能提高去势雄性大鼠阴茎对外部刺激的兴奋性,缩短勃起潜伏期;增加去势雄性大鼠附性器官的重量系数;能促使垂体、肾上腺重量系数增加,调节胸腺、脾脏的重量;明显升高大鼠血清睾酮、皮质醇含量;使氢化可的松所致阳虚小鼠各项症状得到缓解甚至消失。结论温阳益肾胶囊具有益肾壮阳的功效。

Resected area from thymus and all lipoid tissue in the front mediastinum.

切除范围从全胸腺组织到前纵隔和上纵隔的所有脂肪样软组织。

The luminescence intensity of suspended immune cells (1×10〓 cells/ml) from peripheral blood, anterior kidney and spleen of grass carp, which were from two groups immunized with being injected Aeromonas hydrophilia and unimmunized respectively, were detected by means of BPCL4 Intelligentized Ultraweak Luminometer, the datum that were dealt with statistics demonstrated that luminescence intensity of the cells from all kinds of immune organs and blood were intensified after the fish were immunized in two weeks and the luminescence intensity from anterior kidney cells was the highest, mitogens had the enhancing effects. Luminol could strengthened luminescence intensity.

把未免疫的和经过嗜水产气单胞菌注射免疫的草鱼外周血、前肾、胸腺和脾脏以及它们的悬浮细胞(密度控制在1×10〓个细胞/ml左右)分别用BPCL4智能化微弱发光测量仪测量各组的发光强度,结果显示:草鱼各类免疫器官与细胞在免疫两周后发光强度增加,肾细胞的发光强度最大;有丝分裂原具有增强作用;化合物鲁米诺能提高发光强度。

Thymus gland ; lymph nodes ; histocytochemistry ; Leukemia ; mice

胸腺;淋巴结;组织化学;白血病;小鼠

The control tissues were negative.Four 45-day-old SPF pigs infected with PRRSV BJ-4 isolate and four stillborn fetuses were deteced with the probe.Positive hybridization signals could be detected in lung,tonsil,lymph nodes,thymus gland,brain,etc.

应用探针对人工感染PRRSV北京分离株BJ-4的4头SPF猪及4例死胎的组织进行了检测,均可在肺门淋巴结、胸腺、脑、扁桃体等组织中发现阳性杂交信号。

The BMPRⅠA gene are expressed in ovary, liver, skeleton muscle, small intestine, fat, uterus, kidney, heart, lung, pancreas, testis, galactophore, rumen, spleen, lymph and thymus gland.

在牛卵巢、肝、肌肉、小肠、脂肪、子宫、肾脏、心肌、肺、胰腺、睾丸、乳腺、瘤胃、脾脏、淋巴、胸腺等组织中都检测到有BMPRⅠA基因表达。

Methods NIH mice were given TCE injection subcutaneously. Organ coefficients of thymus, spleen and liver were measured in addition to plantar swelling test and lymphopoiesis test.

给予NIH小鼠皮下三氯乙烯染毒后研究胸腺、脾、肝脏等脏器系数变化情况、进行足跖肿胀实验、脾细胞转化实验等。

GanLe capsule can regulate the engulfing index of little mices serum anthracic,can increase the contain of serum hemolysin,and the contractible thymus by CTX,but it have no effect to the T- lymphopoiesis out of body.

肝脏病理检查发现,肝乐胶囊用药组病理损伤较病毒对照组轻。免疫试验结果表明肝乐胶囊能提高小鼠血清碳粒廓清指数(P〈0.05);增加小鼠血清循环抗体的含量(P〈0.05);对抗CTX致小鼠胸腺萎缩的作用(P〈0.001)。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。