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X-ray examination demonstrated that at 4 weeks after implantation, some or even lateral intertransverse bridging regions were unclear, and material density in the repairing group was lower than control group; at 8 weeks after implantation, interspace between up and down bridging was shrunk, and a great quantity of calluses were successively formed; at 12 weeks after implantation, complete confluence was observed, and the density in the repairing group was closed to that in the control group.

结果:采用脱蛋白处理后的松质骨可见大小不等、相互交通、开放孔隙的网架结构,孔径200~500 μm,孔隙率60%左右,其无机成分为羟基磷灰石,有机成分为胶原,力学性能保存良好,细胞相容性良好。X射线片结果显示:植入第4周,横突桥接处部分区域模糊,以内侧明显,此时修复组材料密度略低于对照组;第8周上下桥接部间隙变小,大量连续骨痂生成;12周后完全融合,两组材料密度接近。

The coral/col lagen/rhBMP-2 composite possesses a superior osteoinduction and will be a new type of bone substitute to be used in orthopedic and maxillofacial surgery.

珊瑚/胶原/rhBM P-2复合人工骨具有良好的异位诱导成骨活性,是一种较理想的骨移植替代材料。

It starts transmitting information by integrating with lagen and stromatin by irritating osteocytes and chondrocytes to form rapidly extracellular matrix so as to promote repair of bone and cartilage injury.

转化生长因子β通过刺激骨、软骨细胞合成胶原和基质蛋白,快速形成细胞外基质,达到其促进骨、软骨损伤修复的作用。

Mechanistically, the irradiation was found to alter the salient toughening mechanisms, manifest by the progressive elimination of the bone's capacity for plastic deformation which restricts the intrinsic toughening from the formation "plastic zones" around crack-like defects. Deep-ultraviolet Raman spectroscopy indicated that this behavior could be related to degradation in the collagen integrity.

机械性能方面,放射能明显的改变骨的韧性,骨的塑性形变能力被进一步降低,在破裂样损害周围形成&塑性区&,深紫外线拉曼光谱检测显示,这种现象和胶原完整性的降解有关。

Brane, such as synoviocytes, macrophages, osteoclasts and TNF-αvv acts on different kinds of cell in synovial memchondrocytes, which can produce metalloproteinase,collagenase, stromelysin and so on, further induce pannus formation, joint inflammation, bone erosion and cartilage degradation.

TNF-α可作用于RA关节组织中的滑膜细胞、巨噬细胞、软骨细胞和破骨细胞,使这些细胞活化,产生金属蛋白酶、胶原酶、基膜溶解酶等,导致局部炎症反应和血管翳形成,进一步引起软骨破坏和骨侵蚀。

Secondly, the self-adaptive models of porcelain, metal base, cement, dental root, gutta percha point, periodontal membrane, cancellous bone and cortical bone were reconstructed based on the post-core crown parameters.

将读取数据导入Pro/E软件中,先将桩核冠进行参数化(参数包括桩核冠的直径、长度、锥度、倒角等等),同时根据桩核冠的参数,分别建立可随桩核冠参数变化而自适应变化的饰瓷、金属基底、粘固剂、牙本质、牙胶尖、牙周膜、松质骨和皮质骨的实体模型。

MTA was used to manage clinical problems. These included pulpless permanent teeth with incomplete root formation and perforation in roots or furcations. Total 10 cases (12 teeth), former 7 cases (7 teeth) and latter 4 cases (5 teeth), were present. The follow-up periods were various from 6m to 21m.

应用免疫组织化学手段,观察细胞外非胶原蛋白骨唾蛋白(bonesialoprotein,BSP)、骨桥素(osteopontin,OPN)和骨钙素(osteocalcin,OC)在根尖周组织愈合期间的表达,尤其是在与倒充填材料直接相邻区域的表达。

Methods: The mice for experiment were immunizied with subcutaneous injection of type Ⅱ collagen to induce arthritis after ovariectomy. Severity of joint swelling, radioimmunoassay of serum estradiol (E2),osteocalcin and tumor necrosis factor, and pathological changes of joint, including changes on synovia, articular cartilage and bone, were observed once weekly.

切除小鼠卵巢后,Ⅱ型胶原皮下注射以诱导关节炎;每周1次观察小鼠的关节肿胀程度;组织切片光镜下观察小鼠滑膜、关节软骨及骨的改变;放射免疫法检测小鼠血清雌二醇、骨钙素、肿瘤坏死因子的变化。

Methods: In order to discuss the JIANGU granule treatment GIO molecular action mechanism, this research takes the osteoporosis sickness animal experimentation model by the glucocorticoids-induced induction domestic rabbit, through HE dyeing research Chinese native medicine JIANGU granule to vacancy bone sunken number influence; Through the immunity histochemistry technology,observes the blood vessel bast growth factor in the bone tissue expression. Through home position hybrid technology,in mRNA member level research, collagen I mRNA distribution and expression.

本研究以糖皮质激素诱导的家兔作为骨质疏松症动物实验模型,通过HE染色研究中药健骨冲剂对骨组织的空缺骨陷窝数的影响;通过免疫组织化学技术,观察血管内皮生长因子在骨组织的表达;通过原位杂交技术,在mRNA分子水平研究,Ⅰ型胶原mRNA在骨组织中分布及表达。

Hydrophobically modified anion polyelectrolytes based on Fenugreek gumwere prepared by fixation of dodecyl or cetyl chains onto carboxymethyl Fenugreek gum backbone via ester functions.

将十二烷基与十六烷基以酯键方式分别引入经羧甲基化改性的香豆胶大分子骨架上,制备了基于香豆胶的疏水改性阴离子聚电解质衍生物。

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