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胶质细胞瘤

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Objective To study the differentiation of human glioma cells BT-325 induced by sodium butyrate in vitro.

目的 研究丁酸钠体外诱导人脑多型性胶质母细胞瘤细胞系 BT-325细胞的分化。

The expression absence of LRRC4 was ascribed to the loss of homozygosity of 7q32-ter in U251 cell lines. Conclusion The expression of LRRC4 gene is absent in glioblastoma cell lines, and it offers the important experiment proof for LRRC4 to act as a new candidate of brain tumor suppressor gene from glioma.

通过对胶质瘤细胞系基因组DNA中LRRC4的ORF序列的PCR扩增和测序分析,发现SF126,SF767,M17细胞中,ORF序列第279位氨基酸的第3个密码子存在同义点突变(3/5),而U251和U87细胞基因组DNA中发生了LRRC4基因的缺失突变(2/5)。

OBJECTIVE: To explore inhibitory effects of the human amniotic mesenchyme stem cells on C6 glioma cells.

目的:探讨人羊膜间充质干细胞对C6胶质瘤细胞生长的抑制作用。

Objective To study the sensitivity of radiotherapy on the cells in midsection and edge of glioma.

目的 探讨胶质瘤中心部位及瘤周细胞对放疗的敏感性。

Previous studies have shown thatlymphocytes from patients with malig-nant disease, when encountering abasic protein fraction isolated fromhuman glioma, display a slowingeffect to macrophage electrophoreticmobility.

对用人脑胶质瘤碱性蛋白免疫的38只豚鼠和23只对照组豚鼠进行了巨噬细胞电泳试验,其巨噬细胞电泳减缓率免疫组为6.13±1.06%,对照组为0.96±0.90%;经统计学处理,两组间有显著区别,表明GBP能激发豚鼠的细胞免疫反应性。

Methods:Inhibition of proliferation was measured using MTT colorimetric assay and cell cycle distribution was analysed by flow cytometry.

采用MTT比色法测定大鼠脑胶质瘤C6细胞增殖抑制作用和流式细胞术进行细胞周期分析。

Materials and Methods: Two cases of brain tumors (one was glioblastoma, the other was central neurocytoma) were performed dynamic enhanced CT and DSC-T2~* MR perfusion imaging before operations.

材料和方法:术前对2例脑肿瘤(1例胶质母细胞瘤,另1例中央神经细胞瘤作为对照)分别行动态对比增强CT灌注和动态T2~*敏感对比增强平面回波(DSC-T2~*)MR灌注成像,分析两种灌注方法的rCBV、CBF结果。

In contrast, 11/15 primary glioblastomas contained a significant CD133 subpopulation that displayed neurosphere-like, nonadherent growth and asymmetrical cell divisions yielding cells expressing markers characteristic for all three neural lineages.

相反,15个原代胶质母细胞瘤中有11个含有明显的CD133阳性亚群,呈神经球样,非附着性生长和非对称性细胞分裂,后者产生表达所有三种神经细胞系的特征标志物的细胞。15

Transient in vitro exposure to BMP4 abolishes the capacity of transplanted GBM cells to establish intracerebral GBMs.

骨形成蛋白4在体外很快就可停止移植的恶性胶质瘤细胞构建瘤体的能力。

Methods A total of 55 cases including glioblastoma ( n =17), metastasis ( n =19), radiation necrosis ( n =11) and brain abscess ( n =8) were analyzed.

55例脑内环状强化病灶,胶质母细胞瘤17例、转移瘤19 例、放射性坏死11 例,脑脓肿8 例。

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