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胶质细胞

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Mouse embryonic stem cells can give rise to ectodermal derivatives in culture and can be further induced into neurons and glia for cell-replacement therapies in the central nervous system and for use in drug discovery.

小鼠胚胎干细胞(embryonic stem cell , ES cell)体外培养可以分化成为外胚层组织,并进一步分化为神经元和神经胶质细胞。这些细胞已用于中枢神经系统疾病细胞替代治疗和治疗药物研发。

Methods:Special culture was performed in the fetal rat ependyma or adult rat bone marrow,respectively.

以细胞克隆及免疫细胞化学方法判断NSC增殖并鉴定NSC、神经元和神经胶质细胞

Results The main pathologic changes of high dosage group were inflammatory cell infiltration into the tissues around injecting location, subarachnoid space, and ependyma.

高剂量组动物脑组织主要病理改变为给药部位周围脑组织、蛛网膜下腔、室管膜的炎细胞浸润,炎细胞主要以胶质细胞、单核、淋巴细胞为主,没有脑组织的变性坏死。

It also express in the ependymal cell.2. The immune expression of AQP4 reinforce after MCAO. The relationship between the level of immune expression reinforcement of AQP-4after ischemia and the change of brain water content and ion content is parallel.

结果:1。 AQP4主要分布在脑血管周围的胶质细胞、脑室脉络丛上皮细胞、室管膜细胞的膜上;2。

In the present study changes of NOS positive cells after injection of LPS and apoptotic ependymal cells, the relationship between expression of immediate early gene c-fos and astrocytes, and comparison of changes between SFO and rest regions of the brain in different time-points were investigated with NADPH-d histochemistry, apoptosis in SITU detection of TUNEL, TEM and SEM, fluorescein double labeling of immunohistochemistry, and laser scanning confocal microscope .

为了证实穹窿下器在脑内免疫调节系统中的作用,在本研究当中,应用了NADPH-d的组化方法、TUNEL末端标记法、扫描及透射电镜方法、免疫组织化学的荧光双标法及激光扫描共聚焦显微镜技术,来研究在腹腔内给予大肠杆菌内毒素后,脑内的一氧化氮合酶细胞的变化、室管膜细胞的凋亡、早期即刻基因c-fos的表达与星形胶质细胞之间的关系,以及穹窿下器与其它脑区相比较时的特异性改变。

In the present study changes of NOS positive cells after injection of LPS and apoptotic ependymal cells, the relationship between expression of immediate early gene c-fos and astrocytes, and comparison of changes between SFO and rest regions of the brain in different time-points were investigated with NADPH-d histochemistry, apoptosis in SITU detection of TUNEL, TEM and SEM, fluorescein double labeling of immunohistochemistry, and laser scanning confocal microscope.

为了证实穹窿下器在脑内免疫调节系统中的作用,在本研究当中,应用了NADPH刁的组化方法、TUNEL末端标记法、扫描及透射电镜方法、免疫组织化学的荧光双标法及激光扫描共聚焦显微镜技术,来研究在腹腔内给予大肠杆菌内毒素后,脑内的一氧化氮合酶细胞的变化、室管膜细胞的凋亡、早期即刻基因(immediate early genes沁-fos的表达与星形胶质细胞之间的关系,以及穹窿下器与其它脑区相比较时的特异性改变。

Overexpression seemed to be regionally selective, which involved mainly capillary endothelial cells and astrocytes in epileptogenic areas of the brain.

在癫痫病灶内广泛分布的MRP1免疫阳性细胞主要为毛细血管内皮细胞和星形胶质细胞

Results Astrocyte of rat optic nerve was cultured and purified,which showed positive reaction to glial fibrillary acidic protein.

组织块原代培养,振荡法分离纯化视神经的星形胶质细胞,对细胞的损伤小、纯度高,是快速得到该细胞的理想途径。

A differential diagnosis is pilocytic astrocytoma, which could look like oligodendroglioma focally.

鉴别诊断是毛细胞型星形细胞瘤,它可以局灶呈少突胶质细胞瘤样。

Microglia BV2 was produced by Cell Research Institute of Chinese Academy of Sciences.

实验中小胶质细胞的替代细胞 BV2由中国科学院细胞研究所生产。

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