胶质细胞

Objective To study the occurence, development and regulation of reactive gliosis with astrocyte in vitro.

目的 研究体外星形胶质细胞反应性胶质化的发生、发展过程与规律。

Objective: To investigate the effects of acupuncture on astrocyte proliferation in hippocampus after focal cerebral ischemia reperfusion in rats.

目的：通过针刺对脑缺血后星形胶质细胞增殖进行十预，以探讨其对胶质增生的影响。

RESULTSdiabetic rats showed typical symptoms involving elevated serum glucose and weight loss (2)The rats in DM+VaD group reacted slower and made more error numbers in Y-maze than the rats in VaD group did, with a prolonged total reacting time in a whole day.(3)More neurons with serious damages, such as edema, ischemia or pyknosis could be found in DM+VaD group than in VaD group. More disarrangement of cone neurons, obvious glia proliferation, and more neuron apoptosis were found in CA area of hippocampus. CONCLUSIONS (1)2-VO in STZ-induced diabetic rats succeeded in establishing VaD animal models.(2) The cognitive dysfunction induced by VaD rats had been deteriorated by diabetes mellitus.(3)Morphology evidences proved that diabetes mellitus aggravated brain damages induced by VaD.PART II Effect of diabetes mellitus on the cholinergic nervous systemin CA1 area of hippocampus of VaDOBJECTIVE To estimate the role of cholinergic nervous system in hippocampus during the process of cognitive dysfunction aggravated by diabetes mellitus in DM+VaD group. METHODS Observe the changes of ChAT protein by immunohistochemistry stain. Chose three rats randomly from each group at each pointat two week, four week, and eight week, then sepa

经腹腔注射链脲佐菌素诱导慢性实验性糖尿病，1周后永久性结扎双侧颈总动脉(2-VO)制作VaD模型记录术后2周、4周和8周各组大鼠的体重及血糖；应用Y-迷宫检测空间定向学第二军医大学博士论文中…丈摘…要1ia；一色恤~﹁染澎糕行HE染色观察组织病理学孪叱；胶质细胞原纤维酸性蛋白protellZ，Cf冰尸标记观察星形胶质细舱的激活情况、橄声软公点娜育票票众糯黑橄居端粗默孺篇筑价井袱第二部分糖尿病对血管性痴呆大鼠海马c心区胆碱能神经系统的影响探讨海马CAI区胆碱能神经系统在糖尿病加重确D一大鼠认知障碍中所实验动物及分组同第一部分，应用免疫组织化学染色方法现察海马CAI{介狱牛第晕军l袭拔常博粗{论义

Antibody of mouse against rat of glial fibrilla acidic protein used to labeling astrocytes of the brain and antibody of rabbit against rat of c-fos labeling c-fos protein in the brain. The second fluorescence antibodies were FITC and Cy3, respectively. Observations of the results and quantitative analysis were conducted with LSCM.

在本实验中，我们应用免疫组织化学的双标方法，用小鼠抗大鼠胶质原纤维酸性蛋白标记大鼠脑内的星形胶质细胞，用兔抗大鼠c-fos标记大鼠脑内的c-fos蛋白，分别应用FITC和Cy3标记的荧光二抗来显示，最后用激光扫描共聚焦显微镜进行观察并定量分析。

Objective To investigate the function of human glia maturation factor gamma to induce the proliferation and differentiation of neural stem cells into astrocytes.

目的 探索γ-神经胶质成熟因子能否促进大鼠神经干细胞增殖并分化成神经胶质细胞。

PTEN mainly expressedin neurons in our experiment and the absence of PTEN expression in glia may be relatewith the development of gliomas.

PTEN可能主要在神经元中表达，其在胶质细胞的缺失可能和神经胶质瘤的发生发展有关。

Within these two neurogenic niches, specialized astrocytes are neural stem cells, capable of self-renewing and generating neurons and glia.

在这两个神经发生的微环境中，神经干细胞可分化为特定的星形胶质细胞，能够自我更新并产生神经元和神经胶质。

Results GDNF plays extensive roles in the development and disease of motoneuron.

胶质细胞源性神经营养因子(glialcellline-derivedneurotropicfactor，GDNF)最初是从大鼠胶质细胞系B49的条件培养基中分离纯化获得的一个新的神经营养因子，GDNF为分泌性碱性蛋白质，在中枢神经系统和周围器官中有广泛分布，其表达受不同的转录因子等调控。

In the nervous tissue there are several types of neuroglial cells. In CNS there are chiefly astro

在中枢神经系统十，主要有星形胶质细胞，包括原浆型星形胶质

Methods Rat astroglia were cultured and identified by glial fibrillary acid protein.

体外培养大鼠中脑星型胶质细胞，采用胶质纤维酸性蛋白免疫荧光法鉴定。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。