胶质的

Methods 50 SD rats of C6 brain glioma into the caudate nucleus by stereotactic methods were established.

目的 建立稳定可靠的大鼠C6脑神经胶质瘤模型，并运用1.5 T MRI观察脑胶质瘤瘤体生长的变化规律，为进行脑胶质瘤的在体实验研究提供基础。

Using GSA-〓 lectin histochemistry, the first appearance of microglia occurred at E13, usually stained as scattered amoeboid cells. From then on, the number of microglia increased steadily, reached a peak at postnatal day 7 (P7), and then reduced gradually to adult level. Generally the morphological form of microglia undergoes transformation from early rounded or ameboid to adult resting ramified as they differentiate during development.

使用凝集素GSA-〓亲和组织化学染色，本实验最早观察到小胶质细胞在胚胎13天（E13），为散在分布的圆形或阿米巴样细胞，随后细胞数量逐渐增多；总体而言小胶质细胞的形态遵循着由圆形或阿米巴样逐渐转向纤细分枝状的演变规律，不同阶段细胞形态各有其特点，在不同区域也存在差异；小胶质细胞的数量在生后第七天（P7）达到高峰，其后开始逐步降低直至成年。

Objective: To observe the quantitative and morphological changes of astrocytes in nucleus of solitary tract after vagus nerve stimulation.

目的：观察颈部迷走神经千刺激后孤束核内星形胶质细胞数量、形态的改变，同时在电镜水平观察星形胶质细胞与神经元之间突触形态、数量的变化，从胶质细胞的角度阐明VNS治疗神经精神疾病的重要机制。

Week. Conclusions The S1 area brain glioma model established by this method in rats had the same characters as human brain glioma. The tumor growth period was short and the subsisting period was stable without extracerebral metastasis and extracranial extension. This model is suitable for laboratory and treatment study of brain gliomas.

该方法建立的S1区脑胶质瘤模型具备与人脑胶质瘤生长相似的特性，肿瘤形成时间短，生存期稳定，且无脑外转移和颅外扩散，适合各种脑胶质瘤实验治疗研究。

Methods HE and immunohistochemistry were used to observe the changes of glial fibrillary acidic protein and CD34 in the surrounding areas after cerebral infarction in human.

方法采用HE染色观察星形胶质细胞和微血管的变化，免疫组化技术检测胶质纤维酸性蛋白和CD34在星形胶质细胞和微血管的表达。

In order to explore the function of glia in the progress the experiment was performed both in presence of glia and in the absence of glia The mouse mesencephalic cells were exposed with MPP+ with different concentration. Iloprost was used to investigate whether it can prevent dopamine neuron from the neurotoxic of MPP~..

为了观察胶质细胞在其中的作用，将细胞分为未抑制胶质细胞和胶质细胞抑制组；将不同浓度的MPP~+加入体外培养的中脑多巴胺能神经元培养液中，并加入Iloprost来研究其对MPP~+所导致的神经毒作用是否有保护作用。

On the termination date, the cultured explants were all examined by Western blot, HE and transmission electron microscope. Our results showed that after 12-days in culture, the cultivation treated with AS-ODN reduced the synthesis of AMBN and had a deformed dental cusp with thinner enamel matrix. Ultrastructure analyses showed that there was hardly any cisternae of the rough endoplasmic reticulum in the ameloblasts at the tip of the cusp of AS-ODN treatedexplants. However, on average the enamel matrix was thinner compared with that in the control group. Furthermore, the collagen fibers in extracellular matrix were found disorganized. These findings seemed to provide a direct experimental evidence that tended to indicate that the arrested AMBN translation in cultured tooth germs might result in the delay of the tooth development.

经用Western蛋白印迹检测表明，所设计的反义核酸对AMBN InRNA具有良好的封闭效果并成功阻断了牙胚对AMBN的表达；在缺乏AMBN情况下，与对照组相比，实验组牙胚在体外可以继续生长发育至钟状晚期，出现成釉细胞和成牙本质细胞的分化，成釉细胞可以分化成为分泌期型成釉细胞，胞浆中缺少合成蛋白质所必需的粗面内质网和高尔基氏体，缺乏溶酶体，表明对蛋白合成和脚的能力降低；实验组牙胚有牙尖形成和基质分泌，但牙尖形态异常，基质形成减少，牙尖周围基质最厚处为O.6卜m，明显薄于对照组的5.spin，基质中胶原纤维粗细不等，排列稀疏， 3 第四军医大学硕士学位论文未见钙化现象，充分证明了AMBN在牙胚发育中参与釉质基质形成和矿化过程，影响胶原纤维和牙本质基质的合成，促进成釉细胞对蛋白质的合成和釉质基质蛋白降解。

Results Only DCs cocultured with apoptotic cells can induce special CTLs, while the group of U937 cells and culture cells can not.

结果 与凋亡胶质瘤细胞共培养之DCs可以有效提呈胶质瘤细胞抗原，有强烈的免疫应答，刺激的细胞毒T淋巴细胞特异性杀伤胶质瘤细胞。

TIL of human glioma is of good ability of proliferation in vitro, and this can not be affected significantly by retrovirus-mediated TNF-α gene transduc- tion into it. TIL is suitable as carrier cells for lymphokine gene therapy of human glioma.

1。人脑胶质瘤TIL具有良好的体外增殖能力，逆转录病毒中介TNF-α基因导入人脑胶质瘤TIL后，其体外增殖能力未受明显影响，符合人脑胶质瘤淋巴因子基因治疗运载细胞的要求。

In human vascular smoothe muscle cells and glial cell tumors, ADM suppressed cell growth and increased intracellular cAMP.

ADM也能抑制培养的正常人胶质细胞、胶质瘤细胞及胶质瘤源性细胞系的增殖。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失