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胶质物

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Auricularia auricula colloid-Fe complex was synthesized by Auricularia auricula colloid and FeCl3, and its physicochemical property was determined.

利用黑木耳提取多糖后的料渣,与铁合成黑木耳胶质铁配合物,并测定AGIC的理化性质。

We here demonstrate that graft-deried thymidine analogs can become incorporated into host neural precursors and glia.

然而,我们已经证实,来源于移植的胸苷类似物能够整合进宿主的神经前体细胞和神经胶质。

The hardness and gumminess of the touhua increased as the coagulation temperature, the concentration of GDL and the solid content of soymilk increased.

黑豆豆花之硬度和胶质性随凝固温度、 GDL 浓度、和豆浆中固形物浓度之增加而增加。

Results One case with infantile onset had macrocephaly. The CT scan and MRI showedprominent low-density white matter throughout the cerebral hemispheres. MRI showed prominent also increased T2 signal in the periventricular whitematter. Another patient had an onset at school-age. The CT scan demonstrated brain atrophy. Histological examination on brain biopsy revealed diffuse demyelination and fibrous gliosis.

结果1例婴儿期起病者头颅大,CT扫描示前额明显的广泛性脑白质密度减低特征,MRI示脑室旁白质T2高信号;另1例学龄期起病,CT扫描显示脑萎缩,脑活检光镜下发现脱髓鞘和胶质细胞增生,电镜下观察到大量Rosenthal纤维及不规则的颗粒状沉积物。

Immunocytochemical staining was conducted for the neural stem cells, neuron and neuroglia specific cell surface marker such as nestin, MAP-2, NSE and GFAP.

免疫细胞化学方法检测诱导前后神经前体细胞、神经元和神经胶质细胞特异标记物如nestin,MAP-2,NSE和GFAP的表达。

mechanisms of paraffin deposition in oil production wells, mechanisms of paraffin depositing inhibitors

在原油开采过程中,蜡的沉积物除含有上述烷烃外,还含有不等量的胶质、沥青

Bitumen is similar to the cement and autogenic clay filled in reservoir pores, and it dramatically reduces reservoir porosity and permeability, increases reservoir heterogeneity and even changes the oil/gas accumulation history at a later stage.

沥青类似于充填在储集层孔隙中的胶结物及自生黏土,使储集层孔隙度和渗透率急剧降低,非均质性增强,甚至可改变后期油气的富集规律。

Glioma is still one of refractory disease in the neurosurgical field; the development of new primary and adjuvant treatment is vital. Recently, the gene therapy of glioma is developed rapidly and there are many methods about the gene therapy that include: suicide gene therapy, immunologic gene therapy, drug resistangce gene therapy, angiostatin gene therapy and so on. The sucide gene therapy is the most potential approach of antitumer, these nonmammalian genes encode enzyme that convert nontoxic prodrugs into highly toxic metablites. Cells transfected with suicide genes are targeted for specific negative selection, witch can be induced by administrtion of the corresponding produg. Among the enzyme/produg combinations, two of the best characterized system are herpes simplex virus thymidine kinase /ganciclovir and Escherichia coli cytosine deaminase /5-flourocytosine (5-FC). The formor can convert the antiviral nucleoside analogs acyclovir , ganciclovir to their nucleoside monophosphate derivatives, the monophosphate forms are subsequently phosphorylated by endogenus cellular kinases to triphosphates, these molecules are potent inhibitors of DNA synthesis.

近年来脑胶质瘤的基因治疗发展迅速,应运而生的方法有自杀基因、免疫基因、多药耐药基因以及抗血管生成基因等,其中自杀基因被认为是最有前景的基因治疗方法,它又称病毒介导的酶/药物前体疗法,是利用转基因技术将哺乳动物细胞中所不含有的自杀基因转入到哺乳动物肿瘤细胞中,该基因表达的产物可将无毒的药物前体转化为毒性药物,从而选择性杀伤该肿瘤细胞,常用的自杀基因有单纯疱疹病毒-胸苷激酶基因和大肠杆菌胞嘧啶脱氨酶基因,前者催化无毒性抗病毒核苷类似物如丙氧鸟苷、无环鸟苷等成为单磷酸核苷衍生物,然后在内源性细胞激酶作用下转化为具有明显毒性的三磷酸核苷,作为DNA合成链的终止剂和DNA合成酶的抑制剂,干扰细胞DNA的合成;后者编码的胞嘧啶脱氨酶可催化5-氟胞嘧啶(5-FC)脱氨成为5-氟尿嘧啶(5-FU),然后代谢为有毒性的5-氟尿嘧啶-5′三磷酸(5-FUTP)和5-氟-2′脱氧尿嘧啶-5′磷酸(5-FdUTP),5-FUTP通过与UTP竞争性结合而抑制mRNA和tRNA的合成,5-FdUTP则作用于胸苷合成酶,导致TMP衰竭而阻止DNA的合成,最终诱导肿瘤细胞凋亡。

Curves of grain size distribution for debris flow conglomerates have multiple modes and hence wave sinuously.

颗粒流沉积与之类似,但岩石中基质甚少,砾石之间只充填少量沉积期后渗入岩石中的铁质和粘土矿物等胶结物。

Results: nk 4r immunoreactivity was found extensively localized in neuronal somata and neurite of cerebral cortex, and mainy in layer ⅲ,ⅴ. double labeling experiments confirmed that 100% nk 4r immunoreactive neurons co expressed neun, but not gfap.

结果:nk 4r免疫阳性产物在皮层的锥体细胞层分布最多,在皮层内、外颗粒层、多形层也广泛分布,其阳性产物表达于神经元胞体和突起上,免疫荧光双标结果观察到nk 4r与神经元胞核特异性标记物neun共存(100%,146/146,双标细胞数目/nk 4r阳性细胞数目),且不与星形胶质细胞标记物gfap共存。

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