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胶质

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Objective To study the protective function of estradiol after cerebral ischemia reperfusion and its effect on the expression of GDNF.

目的 探讨大鼠局灶脑缺血再灌注后雌二醇的保护作用及其对胶质细胞源性神经生长因子表达的影响。

Results MRI findings of central neurocytoma are specific in 5 cases. The ganglioglioma was found in the tempora and occipital lobe in 7 cases,in the brainstem in 1 case, cystic-solid tumor was observed in 5 cases with extramural nodule in 3 cases, obviously thickened gyri were revealed in 1 cases and central necrosis in 2 cases.The 3 cases of Lhermitte-Duclos disease include the specific molecular layer imaging features.

结果 5例中枢神经细胞瘤有一定的MRI特征,3例诊断正确。8例神经节细胞胶质瘤中,7例位于或主要位于颞、枕叶,1例位于桥脑和延髓,表现为囊实性者5例,实性部分位于囊外的有3例,呈实性表现为局部脑回增厚者1例,囊变坏死明显者2例。3例小脑发育不良性节细胞瘤有特征性的条纹状或分层状表现。

Ambs S,Dennis S,Fairman J,Stillman IE,Lombardo M.Inhi-bition of tumor growth correlates with the expression level of a human angiostatin transgene in transfected B16F10melanoma cells [J].

本实验将大鼠血清白蛋白分泌信号正确连接在endostatin基因的碳末端,成功构建了真核表达载体pcDNA3-SE,并利用Lipofectamine介导转染C6胶质瘤细胞。

Already have experiment evidence indicate, the spontaneity that brain inner nerve pathological mechanism changes worsens being able to not be controlled , hippocampus nerve basic degeneration appears to escape from loss , galotinous cicatrices takes form and moss shape fibre sprouts waiting for plasticity changing being connected with after this may flare up with acute falling sickness very much.

已有实验证据表明,这很可能与急性癫痫发作后,脑内神经病理变化的自发性恶化不能被控制,出现海马神经元变性脱失,胶质瘢痕形成以及苔状纤维发芽等可塑性改变有关。

Objective To observe and analyze the expression of fasciculation and elongation protein zeta-1 (FEZ1) gene in purified type-1 astrocytes (T1A) and type-2 astrocytes (T2A).

目的 探讨轴突成束和延伸蛋白ζ-1(FEZ1)基因在1型和2型星形胶质细胞(T1A、T2A)中的表达差异,及其在新生SD大鼠中枢神经系统中的表达。

Under electron microscopic observation, capillaries of SFO are fenestrated ones, the endothelium of them are short of the tight junction, their basement membrane are not intact, the gaps between the endothelium and basement membrane are widened, to which the gaps within the endothelium are opened, the end feet of astrocytes surrond the capillaries not completely, and on the luminal surface of the endothelium some small vesicles are adhere to it, all of which suggesting SFO short of blood brain barrier .

在电镜下观察,穹窿下器的毛细血管为窗性毛细血管,内皮缺乏紧密连接结构,基膜薄而不完整,内皮与基膜之间的间隙宽大,内皮裂隙可通向此间隙,毛细血管内皮腔面可见贴壁小泡,星形胶质细胞脚板未完整包围毛细血管,这些结构特点提示SFO的血脑屏障不完整。

Under electron microscopic observation, capillaries of SFO are fenestrated ones, the endothelium of them are short of the tight junction,their basem ent membrane are not intact, the gaps between the endothelium and basement membrane are widened, to which the gaps within the endothelium are opened, the end feet of astrocytes surrond the capillaries not completely, and on the luminal surface of the endothelium some small vesicles are adhere to it, all of which suggesting SFO short of blood brain barrier.

在电镜下观察,穹窿下器的毛细血管为窗性毛细血管,内皮缺乏紧密连接结构,基膜薄而不完整,内皮与基膜之间的间隙宽大,内皮裂隙可通向此间隙,毛细血管内皮腔面可见贴壁小泡,星形胶质细胞脚板未完整包围毛细血管,这些结构特点提示SFO的血脑屏障不完整。

Resuits:Glia maturation factor gamma 、Rho, GDP dissociation inhibitor beta 、Peroxiredoxin-II 、Hypothetical protein 、Beta-actin 、NADH dehydrogenase flavoprotein 2、60S acidic ribosomal protein P0、40S ribosomal protein SA were significantly increased, annexin III was significantly reduced in in rat with intracerebral hemorrhage and cerebral ischemia.

结果:胶质细胞成熟因子等9个蛋白在脑出血和脑缺血模型组表达上调,膜联蛋白III在脑出血和脑缺血模型组表达下调。

Gliomas in children, therefore, are most common in the posterior fossa.

因此,儿童胶质瘤在颅后窝最常见。

It is mainly manifested by café au lait pigmentation, neurofibromas, axillary or inguinal freckling, optic pathway tumor, Lisch nodules, distinctive osseous lesion.

主要表现为咖啡色斑(cafe-au-lait spots, CALs)、神经纤维瘤(neurofibromas, NFs)、腋窝或腹股沟雀斑、视神经胶质瘤、Lisch小体(Lisch nodules,又称虹膜错构瘤)和骨组织病损。

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