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Hours after operation, most nerve cells disappeared and the glial cells were degenerated. There were many mono-nucleus cells infiltrating in transplantation group while a few in control group. One week after operation, tissues in the infarction zone were liquescent with many monocaryons and lymphocytes infiltrating around them in control group.

术后48 h神经细胞大片消失,胶质细胞变性,自体骨髓干细胞移植组有大量单个核细胞浸润,对照组相对较少。1周后对照组梗死区脑组织液化变软,坏死灶周围可见较多的单核和淋巴细胞浸润;自体骨髓干细胞移植组大鼠部分坏死灶被新生毛细血管和胶质细胞增生修复,炎性细胞浸润不明显。

Microglia is always considered to be a kind of most representative immune cell in the central nervous system.

胶质细胞一向被认为是中枢神经系统中最有代表性的免疫细胞,生理情况下小胶质细胞占脑细胞总数的10%左右,其生理功能以吞噬清除细胞残骸为主,保证脑内内环境的稳定。

Methods Number of microglia treated with different doses of nicotine and GM-CSF was determined by MTT assay.

培养的小胶质细胞系(BV-2)中加入不同浓度的尼古丁或尼古丁与粒细胞巨噬细胞集落刺激因子,用MTT方法检测细胞活性,观察对小胶质细胞数量的影响。

Neural stem cells are operationally defined as mitotically competent, self-renewing, and multipotent cells able to differentiate along three main cell lineages in the early neurogenesis (i.e., neurons, astrocytes, and oligodendrocytes).

神经干细胞(neural stem cells,NSCs)广泛存在于胚胎脑组织中,也存在于成年哺乳动物的神经系统。NSCs具有自我更新能力,能够定向分化为神经元、星形胶质细胞和少突胶质细胞。

It is associated with many clinical symptoms;meanwhile, the rise of intracranial pressure caused by is a major reason for morbility and mortality.

它不仅与许多胶质瘤患者临床症状的产生密切相关,同时,它所导致的颅内压升高是造成胶质瘤患者预后不良及死亡的重要原因。

Neuroectoderm; neural crest; neural plate; floor plate; neural tube; neuraxis; neurulation; neuroblasts; stem cells; differentiation; ontogeny; morphogenesis; histogenesis; organogenesis; synaptogenesis; gangliogenesis; embryogenesis; axonogenesis; retinogenesis; gliogenesis; glial progenitor cells; oligodendrocyte progenitor cells; retinal progenitor cells; nerve growth factor; neurotrophic factors; trophic factors; growth factors; neural tube defects; anencephaly; spina bifida; neuroblastoma cells; cell migration; neurogenesis; development; developmental stages

神经外胚层;神经脊;神经板;底板;神经管;轴索;神经胚形成;成神经细胞;干细胞;分化;个体发生;形态发生;组织发生;器官发生;突触发生;gangliogenesis;胚胎发生;axonogenesis;retinogenesis;gliogenesis;神经胶质祖细胞;少突神经胶质细胞祖细胞;视网膜祖细胞;神经生长因子;神经营养因子;营养因子;生长因素;神经管故障;无脑;脊柱裂;成神经细胞瘤细胞;细胞迁移;神经发生;发展;发展进程下一页末页共有 23 条记录,本页从第 1 到第 10 条。

RESULTS: The neural stem cells isolated from neonatal rat brains had the potential of serial passage and proliferation, besides, they express neuroepithelial stem cell protein and differentiate into neurons, astrocytes and oligodendrocytes.

诱导分化后的细胞能表达神经元细胞、星形胶质细胞、少突胶质细胞的特异性蛋白。

If want to changed the stat, must be operatived decrease secondary injury, limited proliferation rate of neuroglial cell, promoted neuron regeneration,after spinal cord injury.

只有有效的降低脊髓损伤后的继发性损害、限制神经胶质细胞的增生速度、促经神经元的再生、才能防止脊髓坏死空洞和胶质瘢痕的形成。

Objective To study the morphology change in apoptosis effect of methylmercuric chloride on brain neuroglioma.

目的 在建立裸鼠皮下U251胶质瘤模型基础上,通过体内实验及相关形态学研究,分析氯化甲基汞的抗脑胶质瘤作用。

Methods The rat models of neuroglioma were established,and divided into two groups. The rats in experimental group were lavaged with MMC 1 week after injected with C6 glioma cells, 10 mg.kg-1every day,the rats in control group were treated with sodium chloride at the same dose.

制备大鼠脑胶质瘤动物模型,将造模成功的大鼠随机分为对照组和实验组,实验组大鼠注射C6脑胶质瘤细胞1周后,每天灌胃给予10 mg.kg-1MMC,连续5 d;对照组给予相同体积的生理盐水。

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