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In this study, immunohistochemical staining was performed with antibodies against D2-40, S100, pankeratin, epithelial membrane antigen, brachyury, and glial fibrillary acidic protein in 4 cases of chordoid glioma, 6 skeletal myxoid chondrosarcomas, 10 chordoid meningiomas, 16 extraskeletal myxoid chondrosarcoma, 18 chordomas, 22 low-grade chondrosarcomas, and 27 enchondromas.

本研究中,我们给4例脊索样胶质瘤、6例骨的黏液样软骨肉瘤、10脊索样脑膜瘤、16例骨外黏液样软骨肉瘤、18例脊索瘤、22例低级别软骨肉瘤和27例内生性软骨瘤做了D2-40、S100、pankeratin、上皮膜抗原、brachyury和胶质纤维酸性蛋白的免疫组化染色。

In order to investigate the effect of tumor necrosis factor α on the activation of astrocyte, the oligodeoxynucleotide was used to inhibit the production of TNF α from astrocytes stimulated by Coriaria Lactone.

为进一步探讨 TNF-α在星形胶质细胞激活中的作用,用 TNF-α反义寡核苷酸抑制由马桑内酯(coriaria lac-tone,CL )诱导的星形胶质细胞 TNF-α的产生,观察 NFκBp6 5核转位和 IκBα降解的变化。

CIK cells are highly efficient cytolytic effector cells which have a stronger significant suppression against growth of glioma in vitro and in vivo.

CIK细胞是一种新型和高效的免疫活性细胞,具有较强的体内外抑制胶质瘤生长的作用,有可能用于临床上脑胶质瘤的过继性免疫治疗。

The brain tissue of the different fetal age rat could be cultured into neural stem cells with the most number of cells for 12.5 dags embryo, which furthermore differentiated into neurons and glial cells.

胎龄为12.5天胎鼠大脑皮质培养出的神经干细胞数量最多,可分化为神经元、神经胶质细胞及少突胶质细胞。

Methods The NGF, BDNF, and NT3 genes of rats were cloned, the eukaryote expression vectors were established, the three kind of recombinant vectors were used to transfect astrocytes, the positive cloned cells were cultured dilatedly after G418 sifting; using supernates of culture liquid of astrocytes modified by gene to culture PC12 or TrkB-PC12, the expression and its level of gene target cells aimed genes were measured by Western blotting or immunohistochemical method.

克隆大鼠NGF、BDNF和NT3基因,构建真核表达载体;3种重组载体分别转染星形胶质细胞,G418筛选后获得阳性克隆细胞进行扩大培养;取基因修饰星形胶质细胞培养液上清培养PC12细胞或TrkB-PC12细胞;用Western blotting杂交或免疫组织化学方法检测基因靶细胞目的基因的表达及其水平。

The activation of glia in the spinal cord was one important reason of the change in substance P excreted from cornu dorsale medullae spinalis. Inhibitor of glia activation will be a new way to treat CP/CPPS.

胶质细胞活化是CP/CPPS大鼠脊髓背角P物质变化的重要原因,胶质细胞活化抑制剂的应用将是治疗CP/CPPS的新亮点。

Following brain stem injury,the number of GFAP-positive astrocytes in cerebral cortex and pervent-ricular area,dorsomedial and ventro-medial pafts of midbrain at 30 min antemortem,and in periventricular area,dorsomedial part of pens,dorso-medial and ventro-medial part of medulla oblongata at 60 min antemortem.

采取针刺法造成实验大白鼠脑干损伤,用免疫组织化学LSAB法检测大脑、中脑、桥脑及延髓等不同部位脑组织中胶质原纤维酸性蛋白的改变。结果发现,生前损伤30min,大脑顶部灰质及中脑腹例中央部的GFAP阳性星形胶质细胞数目增多;生前损伤60min,除大脑顶部灰质及中脑腹侧中央部外。

It has been found that ectogenic GDNF has nervous protective effec,but ectogenic GDNF cannot enter blood brain barrier.

传统观点认为,星形胶质细胞是神经系统的支持细胞,构成神经组织的网架而起支持作用,与神经元的解剖位置关系紧密,参与中枢神经系统的免疫反应,参与构成血脑屏障,目前研究发现,脑缺血时星形胶质细胞异常活跃,通过合成多种蛋白质、细胞因子和神经营养因子等对神经元起保护作用,对缺血性脑损伤的发展和转归具有重要意义。

Results In control group, AQP4 protein and its mRNA were expressed in subpial astrocytes, choroid plexus, ependyma and perivascular astrocytes.

结果AQP4及其mRNA在软脑膜下星形胶质细胞、脉络膜丛、室管膜及血管周围星形胶质细胞胞膜上均有表达。

The main differential diagnosis of a tumor located in the trigone of the lateral ventricle should include choroid plexus papilloma in patients under 10 years of age; low-grade gliomas, such as ependymoma, oligodendroglioma, and low-grade astrocytoma in patients between 10 and 40 years of age; and metastases and meningioma after the 4th decade of life.

位于侧脑室三角区的肿瘤其主要的鉴别诊断应该包括脉络膜乳头状瘤(小于10岁);低级别的胶质瘤,如室管膜瘤、少突胶质细胞、低级别的星形细胞瘤等(10-40岁患者),大于40岁的要考虑的转移瘤和脑膜瘤。

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