胶束

OBJECTIVE:To investigate the use of micellar paper chromatography on the isolation and identification of flavonoids and their soluble derivatives.

目的：探讨胶束纸色谱法在分离、鉴别黄酮类及其水溶性衍生物中的应用。

The diameter of fat ball and casein micelles in Ultra high pressure sterilized milk is measured by both Numeral microscope(DMBR-400) and Scan electron microscopy(JSM-6360LV) respectively,and is contrast with original milk,pasteurism milk as well as ultra high temperature sterilized milk.

采用DMBR-400数码显微镜和JSM-6360LV扫描电镜分别对超高压杀菌乳中的脂肪球和酪蛋白胶束的直径进行测定，并且与原乳、巴氏杀菌乳、超高温瞬时杀菌乳进行比较。

In situ recirculation model was used and the concentration of nobiletin in the perfusate were determined by HPLC.

川陈皮素微乳在空肠的吸收速率最快，吸收速率常数Ka为(0.5298±0.0507)h-1；川陈皮素胶束在空肠段的吸收显著低于微乳组(P.05)。

Compared with HA in water-contained organic solvents, the pigment in micelle had higher pKa value and higher fluorescence quantum yield. Moreover, the quantum yield of active species produced from photosensitization, 1O2 and ·OH, increased as well. As a result, the photosensitivity of HA was enhanced.

相对于含水有机体系，HA在胶束中基态的 pKa值升高，荧光量子产率增大，光敏反应产生的活性中间体1O2 和·OH的产额增加，从而提高了其光敏活性，这在光敏损伤作用中具有重要的生物学意义。

The fluorescence characteristics of the complex of piperine with cation in micellar system were studied.At the same time,the influence of experimental condition on the fluorescence intensity was also studied.

研究了金属离子存在下胡椒碱在胶束体系中的荧光特性及实验条件对荧光强度的影响。

Chapter 4 gives a micellar electrokinetic chromatography method for the quantitative analysis of seven podophyllum lignans in podophyllum emodi wall.

第四章：建立了胶束电动毛细管色谱法分离测定抗癌药物桃儿七中七种主要有效成分的新方法；利用二阶导数电泳图定量测定低含量和在实际样品没有达到基线分离的组份。

In chapter 6, seven pairs of diastereoisomers of podophyllum lignans at C4-position, including three pairs of spin labeled compounds, were separated by MEKC with 20mM sodium tetraborate-30mM SDS-10％ 2-propanol (pH=9.5-9.7) within 20min.

第六章：首次利用胶束电动毛细管色谱分离了七对抗癌药物鬼臼类木脂素在C4位的差向异构体，该方法可用来鉴定分析物的纯度、确定自旋标记化合物C4-H的构型等，为研究差向异构体不同的抗癌机制提供检测手段。

Objective To introduce the application of polymeric micelles in the field of pharmacy.

摘要介绍聚合物胶束在药学领域的研究进展。

The dissolubility of PPLA in water was (2.16～4.32)×10－2 mg·mL－1 according to eye judgment. The critical micelle concentration was 2.16×10－2 mg·mL－1 obtained from a fluorospectrophotometer. The self-assembled aggregates of PPLA in water were nanoscale spheres observed by a transmission electron microscope. The particle size and zeta potential tests by dynamic light scattering revealed that during preparation, the ratio of hydrophilicity/hydrophobicity, the aqueous medium and the pH had great influences; while dilution, freezing and pH change to basic condition had no effect after preparation, but pH change to acidic condition made the nanoparticles precipitate.

目测法得到其溶解度为(2.16～4.32)×10－2 mg·mL－1；荧光法得到聚合物的临界胶束浓度为1.12×10－3 mg·mL－1；透射电子显微镜观察显示该聚合物在水中的自组装聚集体为纳米级球形；动态激光光散射测试微球的粒径和Zeta电位发现，在微球的制备过程中，聚合物的亲/疏水性比例、水相介质及水溶液的pH值对它影响显著；而制备后，稀释和冷冻对它无显著影响，改变微球的环境pH值至酸性，出现聚集，至碱性无影响。

A study of Chemically Induced Dynamic Poiarization spectra is made, using a highly time resolved ESR, of photolized anthracenequinone radicals to determine the influence of surfactant micelles on the spin polarization of anthracenequinone anion. It is found that the CIDEP mechanism of photolization is mainly the radical pair mechanism of anthracenesemiquinone radical and of ethylene glycol ketyl R〓〓 or R〓 radical whose center is carbon in anthracenequinone/ethylene glycol system, but there is a certain amount of triplet state mechanism polarization.

分别研究了胶束和微乳液的"笼效应"对蒽醌和苯醌的光解CIDEP的影响，其结果如下：(1)对于蒽醌的CIDEP，在乙二醇溶剂中，极化的蒽醌自由基AQ〓和R〓自由基通过光解经过夺氢反应产生，其CIDEP机理主要是自由基对机理，但也包含了一部分三重态机理。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失