胶原质

Human/rat homology collagen type I siRNA plasmid not only direct repress collagen type I gene expression in rat inesangial cells, but also have the same inhibition action of TGF-β1 induced overexpression of collagen type Ⅰ.

本实验构建的人鼠同源Ⅰ型胶原siRNA质粒，在大鼠系膜细胞内不仅能够直接抑制Ⅰ型胶原的基因表达，而且对TGF-β1诱导的I型胶原表达增加同样具有较好的抑制作用。

FN and LN (the non-collagenous index) out of ECM were measured by immuno-histochemistry mean, and the accumulation of ECM was measured by typeⅠand Ⅲ collagen ,α-SMA was chosen as a symbol of the activated reposit fat cell. TGF-β〓 was chosen as a symbol of the cellular factor made the reposit fat cell activated. We observed the mechanism of 286 through the variety of the upper indexes during the experiment.

用免疫组化方法测评肝细胞外基质中的非胶原指标FN、LN，胶原指标Ⅰ、Ⅲ型胶原等在实验过程中的变化作为判定ECM沉积增多的事实指标；用a-平滑肌肌动蛋白作为贮脂细胞被激活的标志物指标；用转化生长因子-β〓作为激活贮脂细胞的细胞因子指标；通过观测上述指标在实验中的变化，来探讨"268方"的作用机理。

FN and LN(the non-collagenous index) out of ECM were measured by immuno-histochemistry mean, and the accumulation of ECM was measured by type I amd III coHagen, a -SMA was chosen as a symbol ef .the activated reposit fat cell.TGF- P1 was chosen as a symbol of th ieccellular factor made the reposit fat cell activated.We observed the mi sclnanism of 286 through the variety of the upper indexes during the experiment.

用免疫组化方法测评肝细胞外基质中的非胶原指标FN、LN，胶原指标Ⅰ、Ⅲ型胶原等在实验过程中的变化作为判定ECM沉积增多的事实指标；用a-平滑肌肌动蛋白作为贮脂细胞被激活的标志物指标；用转化生长因子-β_1(TGF-β_1)作为激活贮脂细胞的细胞因子指标；通过观测上述指标在实验中的变化，来探讨"268方"的作用机理。

Black wattle tannin was immobilized on collagen fiber by aldehydic cross-linking reaction to prepare a novel adsorbent,and its adsorption behaviors toward scandium ion(Sc3+)were investigated.

以胶原纤维为基质，通过醛交联剂将黑荆树单宁固化在胶原纤维上，制备了胶原纤维固化黑荆树单宁吸附材料并研究了IBWT对钪离子(Sc3+)的吸附特性。

Black wattle tannin was immobilized on collagen fiber by aldehydic cross-llnking reaction to prepare a novel adsorbent, and its adsorption behaviors toward scandium ion（ Sc^3＋） were investigated.

以胶原纤维为基质，通过醛交联剂将黑荆树单宁固化在胶原纤维上，制备了胶原纤维固化黑荆树单宁吸附材料并研究了IBWT对钪离子（Sc^3＋）的吸附特性。

Tissues of the infundibular septum from 22 patients with TOF were studied and 8 patients without cardiovascular disease and collagen system disease were used as control.The collagen concentration were determined by biochemical methods,the heart function were determined by pressure curve in right ventricle.

用生化方法定量分析22例法洛四联症患者和8例非心血管及胶原系统疾病尸检者的右室心肌间质中的胶原含量和Ⅰ/Ⅲ型胶原比值，并用右室穿刺法测定反映法洛四联症患者右室收缩及舒张功能的dp/dtmax及-dp/dtmax。

Primary cultured chondrocytes are poly-angle, cytoplasm-rich, and their nuclei are either round or oval with clear necleole. Metachromatic and alcian blue positive staining in primary cultured chondrocytes was observed. Intercellular matrix was anti-collagen type Ⅱ staining but not anti-collagen type Ⅰ staining by IHC assay.

原代培养软骨细胞呈多角型，胞质丰富，胞核成圆形或椭圆型，核仁清楚，甲苯胺蓝呈异染性，阿尔新蓝8Gx 染色阳性，细胞外基质Ⅱ型胶原免疫组化染色阳性，Ⅰ型胶原染色阴性。

And Sirius Red in a supersaturated picric acid solution viewed by polarization microscopy. The changes of mRNA expression of collagen type I were analyzed by RT-PCR. The results were compared with those after intervention with Losartan.

染色及苦味酸天狼猩红胶原特异染色偏振光显像进行心脏间质胶原的组织化学观察，RT-PCR观察心脏I型胶原mRNA表达的变化，并与氯沙坦干预后比较。

Whereas osteoporosis is unassociated with bone pain, osteomalacia has been associated with isolated or generalized bone pain.39,40 The cause is thought to be hydration of the demineralized gelatin matrix beneath the periosteum; the hydrated matrix pushes outward on the periosteum, causing throbbing, aching pain.7 Osteomalacia can often be diagnosed by using moderate force to press the thumb on the sternum or anterior tibia, which can elicit bone pain.7,40 One study showed that 93% of persons 10 to 65 years of age who were admitted to a hospital emergency department with muscle aches and bone pain and who had a wide ariety of diagnoses, including fibromyalgia, chronic fatigue syndrome, and depression, were deficient in itamin D.41

然而，骨质疏松症与骨痛无关联，而软骨病则与局部性或全身性骨痛有关。其原因被认为是骨膜下已去矿质化的胶原基质上发生的水合反应，水合的胶原基质在骨膜上向外扩张，引起阵痛。软骨病可通过以拇指适度挤压胸骨和胫骨前方以引起骨痛感。一项研究显示10岁到65岁中有93%的人向医院急诊室承认有肌肉疼痛和骨痛症状，他们还有一些其他症状包括纤维肌痛、慢性疲劳综合征、抑郁等，该研究显示他们都缺乏维生素D。本人已认领该文第9、10两部分，48小时后若未提交译文，请其他战友自由认领。本人已认领该文11、12部分编译，48小时后若未提交译文，请其他战友自由认领。本人认领第十三部分，48小时内交稿请战友纠错！

PART 1 EXPRESSION OF MMP/TIMP IN SKELETAL MUSCLE OF ARTERIAL OCCLUSION DISEASE MODELS OF DOG'S HIND LIMB Objective To study the distribution changes of typeⅠand typeⅢcollagen in skeletal muscle of arterial occlusion disease models of dog's hind limb and the expression of MMP-2/TIMP-2 in skeletal muscle of arterial occlusion disease models of dog's hind limb. To investigate the significances of collagen metabolism and MMPs in skeletal muscle remodeling due to ischemia.

第一部分MMP/TIMP在犬后肢动脉闭塞性病变模型骨骼肌中表达的变化目的研究Ⅰ型胶原、Ⅲ型胶原在犬后肢动脉闭塞性病变模型骨骼肌的分布变化以及MMP-2、TIMP-2在犬后肢动脉闭塞性病变模型骨骼肌表达的变化，探讨胶原代谢和基质金属酶系统在缺血导致的骨骼肌重塑中的意义和作用。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失