胶原质

At the 8 week postoperatively,three groups still have not restored the normal thichness of corneal epithelial cell;but in the blank group there was more neoformative irregular collagen in the anterior stromal layer.

术后4周，三组覆盖切削区的角膜上皮细胞仍有轻度增生，空白组前基质层内较多新生胶原，排列不规则，失去板层结构，瘢痕形成。

METHODS: A total of 50 white rabbits were randomly divided into anterior cruciate ligament transection group, medial collateral ligament transection + meniscectomy group and normal control group. The specimens were harvested at weeks 1, 2, 3, 4, and 5 after operation. The osteocartilaginous section of the medial femur condyles were observed by gross observation, histological examination, and Markin scores. The contents of proteoglycan and collagen fiber were also measured.

取大耳白兔50只，随机分为3组前交叉韧带切除组、内侧副韧带+半月板切除组分别切除右后肢前交叉韧带、右后肢内侧副韧带和半月板，正常对照组不干预，分别在建模1，2，3，4和5周后分批于膝股骨内髁软骨取材，进行软骨组织大体和组织学观察、软骨损伤程度Markin评分；测定软骨组织蛋白多糖及软骨基质中胶原纤维含量。

Objective: To study the survival and distribution of allogenic mesenchymal stem cells after implantation into other rabbits, evaluate osteogenetic effectiveness of collagen-sponge mixed with allogenic BMscs of rabbit in repairing of radial shaft defects, and lay the foundation for further application.

目的：了解兔骨髓间充质干细胞同种异体移植的存活分布情况及同种异体兔BMses复合胶原海绵情况，观察其对兔桡骨1.5cm缺损的修复效果，为将来的进一步应用莫定实验基础。

Objective To evaluate the effectiveness of nano-HA/Collagen in osteonecrosis of the femoral head defect repair.

摘要〕目的研究用纳米晶胶原基骨和骨髓间充质干细胞在治疗股骨头坏死缺损修复的效果。

After osteoplastic induction, peripheral blood MSCs had strongly positive reactions for alkaline phosphatase staining, total collagen staining, alizarin red staining.

外周血间充质干细胞成骨诱导后，碱性磷酸酶染色、总胶原染色及茜素红染色均呈强阳性；成脂诱导后油红染色呈阳性，有一定数量的脂滴形成。

Result: The divided functional recipes of DHZCP could significantly decreased the deposit of lipid and the atherosclerotic plaque area in aorta intima, relieve the histopathological changes of atherosclerosis,and inhibited the proliferation of vascular smooth muscle cells and collagen to reduce pachynsis of vascular intima. The divided functional recipes of DHZCP also reduced IT, IMT and IT/MT and reversed the contractive vascular remodeling.

结果：大黄虫丸各功效组分均能减少家兔主动脉内膜脂质沉积，使AS斑块面积减小（ P 。05）；抑制血管平滑肌细胞增殖和胶原纤维增生，减轻内膜增厚；降低IT，IMT，IT/IMT比值（ P 。05），干预收缩性血管重塑；减轻线粒体肿胀，减少泡沫样细胞形成。

The liver and kidney were partly removed and fixed with 4 % paraform phosphate buffer. The remnant of the liver was stored in liquid nitrogen and -80℃. 4.examination: Serum: ALT, AST, BUN, Scr in serum were measured by biochemical analyses and MDA,SOD by spectrophotometric methods and HA , LN, C-IV by radioimmunological methods.

指标检测：血清：全自动生化分析仪检测血清中谷丙转氨酶、谷草转氨酶、尿素氮、血肌酐的含量，放射免疫的方法检测血清透明质酸、层粘连蛋白、IV型胶原，分光光度计法检测血清中超氧化物歧化酶活性及丙二醛的变化。

Both Fas and NO can lead chondrocyte apoptosis respectively and cause articular cartilage destruction. IGF-Ⅰ, TGF-β, bFGF, BMP and other growth factors are polypeptide agents that can influence cell activity by signal convection. They can accelerate chondrocyte proliferation and proteoglycan synthesis, play the local regulation action on formation and plerosis of bone and cartilage tissue by autocrine or paracrine. They have the ability to induce cartilage formation. Some investigations showed that growth factors can influence chondrocyte metabolism, synthesis of specific Ⅱ type collagen and proteoglycan by co-operation and inhibition. 1. 3 Situation of OA therapeutics The therapeutic methods of OA mainly comprised non-drug treatment, drug treatment, operation treatment, tissue and genetic engineering, et al. Drug treatment is the chief method among them.

若其活性发生改变，则将导致关节软骨基质成分的丢失和进行性破坏；软骨细胞凋亡与OA的发病密切相关，Fas与NO可各自独立介导软骨细胞凋亡，造成关节软骨破坏；IGF-Ⅰ、TGF-β、bFGF、BMP等生长因子是一组通过细胞间信号传递影响细胞活动的多肽因子，具有促进细胞生长、增殖与合成等作用，可通过自分泌或旁分泌方式对骨和软骨的形成和修复起局部调节作用，可促进软骨细胞增殖、分化与蛋白多糖的合成，具有较强的诱导软骨形成的能力，研究表明多种生长因子相互促进、相互抑制，以协同或拮抗方式影响软骨细胞代谢，影响软骨细胞特异性Ⅱ型胶原和蛋白多糖的合成分泌。

Finally, we established rat model of PF induced by bleomycetin, and observed the interventional action of phenol total base to model. The analysis of experimental result including pathematologic and tissue biochemical indicator showed phenol total base of plumula nelumbinis have some therapeutic action to rat model of PF induced by BLM.

通过病理学观测及组织生化指标的检测(SOD、MAD、GSH一PX、Hyp)，说明莲子心酚性总碱对博莱霉素致大鼠肺纤维化有一定治疗作用，可能的作用机制：降低肺纤维时胶原含量；抑制肺成纤维细胞的增殖；抗自由基和抗脂质过氧化作用及提高了机体内GSH一Px含量。

The immunohistochemical location of noncollagenous protein, bone sialoprotein , osteopontin and osteocalcin at different stages following periradicular surgery was undertaken. The crystals formation on surfaces of MTA was evaluated when treated in different conditions without cells in vitro and in vivo. MTA was used to manage clinical problems, including perforations in roots or furcations, and pulpless permanent teeth with incomplete root formation. The study included the following three parts

本研究试图通过体内外研究探讨MTA表面牙骨质形成的机理，动物体内动态观察根尖周组织在用MTA倒充填后的组织反应和细胞外基质非胶原蛋白的表达，体外观察MTA在不同的环境下表面的形态及成分变化，和在体内环境下材料表面磷灰石层的形成，同时结合临床病例观察其临床治疗效果。

Finally, according to market conditions and market products this article paper analyzes the trends in the development of camera technology, and designs a color night vision camera.

最后根据市场情况和市面上产品的情况分析了摄像机技术的发展趋势，并设计了一款彩色夜视摄像机。

Only person height weeds and the fierce looks stone idles were there.

只有半人深的荒草和龇牙咧嘴的神像。