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胶原

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Among scanning electron microscope, the increasing of the cranny of cartilage, the nudity of more collagen fibre that arrange turbulently, even the exposure of subchondral bone in high energy group.

扫描电镜中,高能组于低能组和正常组相比,软骨表面裂隙更加扩大,大量胶原纤维裸露,排列紊乱,甚至有软骨下骨暴露。

CCM is a proper scaffold, on which KC and FB of tympanum maintain satisfactory proliferation and collagen secretion activity.

体外实验证实热干法制备的CCM适合鼓膜KC和FB生长、增殖,FB可以保持良好的胶原分泌功能。

Objective:To investigate the effect of high glucose on the production of reactive oxygen species and type IV collagen in human mesangial cells and the intervention of tea polyphenols.

目的:探讨高糖对人肾小球系膜细胞活性氧、Ⅳ型胶原合成的影响及其茶多酚的干预作用。

The effects of BMP-2, TNF-α and they two synergism in different concentration were also detected. The mRNA expression of cbfal, OC, H-ras, BMPR-IA, type Ⅰ and typy Ⅱ collagen of ligamental fibroblast under the co-stimulation of BMP-2 and TNF-α were detected using RT-PCR technique.

并分析了不同浓度的人重组骨形态发生蛋白-2(rhBMP-2,10ng/ml、100ng/ml、250ng/ml、500ng/ml)和人重组肿瘤坏死因子-α(rhTNF-α,5u/ml、50u/ml、100u/ml、500u/ml)及两者协同作用(500ng/ml rhBMP-2+50u/ml rhTNF-α)对两类细胞系分化方向(细胞形态变化、ALP活性、DNA及胶原合成、骨钙素分泌)的作用。

However, as age increases and there is ultra-violet radiation, collagen gradually hardens and secretion decreases.

但随著年龄增长,以及紫外线曝晒,胶原蛋白会逐渐硬化,并降低分泌量。

RESULTS: The AF cells cultured in different substrates were morphologically undistinguishable. Toluidine blue staining showed that there was also no difference between AF cells cultured on flexible silicone membranes and in plastic plates. The cells growing in different substrates expressed the same levels of collagen typeⅠ,Ⅱ and aggrecan mRNA and integrin β1. AF cells grew well on silicone membranes.

结果:种植于不同基质的纤维环细胞形态学观察无明显差别;在两种基质上的纤维环细胞甲苯胺蓝染色无差异;Ⅰ,Ⅱ型胶原及聚集蛋白聚糖mRNA及细胞膜整合素β1的表达亦无明显差异;纤维环细胞可以黏附于硅橡胶膜上生长。

The scaffolds must be not only unharmful to health, but also easy for cells attachment, and be able to induce collagen deposition to form a neotendon with mechanic properties similar to those of normal tendon.

所选用的支架材料不仅要对人体无毒副作用,还要求其易于细胞黏附,能诱导胶原沉积,新腱形成,并具有接近正常肌腱的力学性能。

Vanadate can effectively induce the prol iferation of fibroblasts and the production of collagen type I in vitro, which may provide a new approach to the treatment of MCL injury.

钒酸盐具有促进MCL 成纤维细胞的增殖和Ⅰ型胶原合成的能力,可能为治疗MCL损伤提供一种新的途径

Objective To investigate the effect of vanadate on prol iferation and collagen type I production of rat medial collateral l igamentfibroblasts.

目的 探讨钒酸盐对大鼠内侧副韧带(medial collateral ligament,MCL)成纤维细胞增殖和Ⅰ型胶原合成的影响。

Increased collagen content, increased cell apoptosis and reduced cell component lead to venous remodeling, and it may be one of the mechanism of varicosity.

静脉胶原含量增加,细胞过度凋亡和细胞构成减少导致静脉血管重塑,可能是静脉曲张发病机理之一。

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