胶原

Results (1) the laminin synthesis was significantly improved by PBMC from nontreatment group (P＜0.05);(2) the 3 H-prolin incorporation was significantl decrease in the GEC treated by PBMC supernatant from nontreatment group(P＜0.05);(3) the supernatant of PBMC from nontreatment group stimulated the collagen Ⅲ synthesis(P＜0.05), while, there was no significant difference of collagen Ⅳ synthesis between 4 groups;(4) the activity of PBMC supernatant have no close relation with urinary protein excretion, pathological type and clinical type.

结果 (1)肾病极期未经激素治疗组PBMC上清明显促进了GEC合成层粘连蛋白；(2)未治PBMC上清抑制了GEC合成总胶原；(3)未治组PBMC上清促进了Ⅲ型前胶原的合成，而对Ⅳ型胶原的合成无明显影响；(4)肾病患儿PBMC的上述作用与是否足量激素治疗有关，而与尿蛋白能否阴转、肾组织病理类型、肾病临床类型等无直线相关关系。

Three other wound dressings were developed by similar method, namely collagen membrane with polyurethane membrane onlay, polyurethane-coated collagen membrane and collagen membrane on gauze.

并以类似的方法研制成聚氨酯膜-胶原海绵复合膜，涂聚氨酯胶原膜，和纱布胶原膜三种创伤敷料。

the fibroblasts are activated in collagen synthesis in active keloid. The enhanced collagen synthesis by fibroblasts is a critical factor leading to the overabundant collagen accumulation in keloid.

结论在活跃增生的瘢痕疙瘩中，成纤维细胞胶原合成功能处于活化状态，胶原合成增加是瘢痕疙瘩中胶原过度积聚的重要原因。

Results Histologically, the tumor was composed of mildly cellular benign-appearing spindle-shaped cells and bands of hyalinized collagen in varying proportions from area to area, and a typical patternless archite...

结果镜下见肿瘤组织由不同比例的纤维母细胞和胶原构成，纤维母细胞分化良好，形态多样，散乱穿梭于胶原蛋白束之间或环绕在玻璃样变的血管周围，伴有局灶性致密区域；胶原成分发生玻璃样变，局部呈轮辐状或瘢痕状排列。

This pattern is characterized by the combination of pro-MMP-2 and membrane type 1 (MT1)-MMP expression, which drie pericellular generation of actie MMP-2 and local degradation of normal lier matrix. In addition there is a marked increase in expression of TIMP-1 leading to a more global inhibition of degradation of fibrillar lier collagens by interstitial collagenases (MMP-1/MMP-13). These pathways play a significant role in the progression of lier fibrosis.

其降解肝正常基质，同时抑制引起肝纤维化的纤维胶原降解，这种情况的特点是前明胶酶A合成和膜型1－MMP表达，使得小叶内细胞激活MMP-2和降解当处的正常肝基质，此外血浆1型组织基质金属蛋白酶抑制剂（TIMP-1）明显升高引起广泛的抑制间隙胶原酶(MMP-1/MMP-13)对纤维肝脏胶原的降解。

To evaluate the role of collagen Ⅰ,Ⅲ and Ⅳ in the formation of the pericystic layer of hepatic hydatid cyst The expression of collagen Ⅰ,Ⅲ and Ⅳ in pericystic layers of hepatic hydatid cysts from 40 patients was observed using immunohistochemical methods.

探讨Ⅰ、Ⅲ和Ⅳ型胶原在形成肝包虫囊肿周围人体纤维囊壁中的作用及其临床意义。采用免疫组织化学方法检测Ⅰ、Ⅲ和Ⅳ型胶原在40例肝包虫囊肿周围纤维囊壁中表达。Ⅰ、Ⅲ和Ⅳ型胶原在肝包虫囊肿周围纤维囊壁中出现特异性分层表达。

Hepatic hydatid cyst ; pericystic layer ; collagen Ⅰ; collagen Ⅲ; collagen

肝包虫；纤维性囊壁；Ⅰ型胶原；Ⅲ型胶原；Ⅳ型胶原

And Sirius Red in a supersaturated picric acid solution viewed by polarization microscopy. The changes of mRNA expression of collagen type I were analyzed by RT-PCR. The results were compared with those after intervention with Losartan.

染色及苦味酸天狼猩红胶原特异染色偏振光显像进行心脏间质胶原的组织化学观察，RT-PCR观察心脏I型胶原mRNA表达的变化，并与氯沙坦干预后比较。

The psammoma body mineralization in meningioma is a common type of mineralizationThe analysis of the mineral composition may provide some support information in finding the reason of happening and developing of the diseaseThis paper focuses on the concentric layered structure mineralization in meningiomas, using mineralogical methods, such as HRSEM, ESEM, EDAX, EPMA, HRTEM, XRD and FTIR to systematically investigate the mineral composition, structure and shape of the minerals in psammoma bodies in meningiomasWe have devised a method for preparing the silicon wafer sheet which was used for the ESEM insitu observations and analysisIn this study, we first got the ESEM and HRTEM images of the initial mineralization phase of meningiomasThese images showed that in the early stage of psammoma body mineralization in meningiomas, many mineralized balls composed of octocaphosphate were precipitated on the collagen fibersThese balls continued to grow and aggregate, and were gradually hydrolyzed to become the dahlliteThe continued development of mineralization resulted in the mineralized collagen fibersThe study revealed that the concentric layered structure of the psammoma bodies in meningiomas is formed by the spiral arrangement of the mineralized collagen fibers on which the mineralized grains precipitated.

砂粒体矿化是脑膜瘤中常见的矿化类型，对其形成机理和矿物成分的分析可能会对肿瘤发生、发展的研究提供辅助信息。该研究选取人脑膜瘤中的砂粒体矿化作为研究对象，采用偏光显微镜、环境扫描电镜及能谱、X射线衍射仪、高分辨透射电镜和电子探针对样品的形貌、结构和成分进行测试分析，并以此为依据探讨脑膜瘤中砂粒体的形成机理。研究结果表明矿化的初期为沉淀在胶原纤维上的矿化小球，成分为磷酸八钙；矿化小球不断生长聚集，并逐步水解为碳羟磷灰石晶体，矿化的不断发展致使胶原纤维也发生矿化。砂粒体的同心层状构造是由螺旋状排列的矿化胶原纤维及沉淀在其上的矿化颗粒组成的集合体，而不是多数研究中所述：砂粒体是以坏死细胞残骸为中心由内至外的同心层沉淀。

As a solvent, it was mixed with various quantity of pigskin collagen powder. During the dissolution, three kinds of heating methods were applied. The one was be heated in water bath directly, the second one was be heated in water by microwave radialization and the third one was be heated by microwave radialization directly.

通过普通水浴加热，微波辐射水浴加热和微波直接辐射加热三种方式研究了离子液体对胶原蛋白的溶解能力，对不同质量浓度的溶液进行傅里叶变换红外测定，分析溶液中的胶原蛋白结构的变化，最后，对溶液进行再生得到皮胶原蛋白膜，并进行红外分析。

Plunder melds and run with this jewel!

掠夺melds和运行与此宝石！

My dream is to be a crazy growing tree and extend at the edge between the city and the forest.

此刻，也许正是在通往天国的路上，我体验着这白色的晕旋。