胶原

Objective After Intense pulsed light irradiation cavia cobaya skin, to evaluate the histological change of skin with HE stains; to evaluate the collagen fiber change with nitroxanthic acid stains; to quantitative analysis of hydroxyproline content. Confirm mechanism of action for Intense pulsed light on sun-damaged human skin.

目的 用强脉冲光照射豚鼠背部皮肤后，通过HE染色观察皮肤组织学的改变；用苦味酸染色观察皮肤胶原纤维的改变；定量分析豚鼠皮肤羟脯氨酸的含量，观察皮肤胶原蛋白的变化，进一步研究强脉冲光治疗皮肤光老化的作用机制。

Results As compared to DM control group, levels of GSP, myocardial enzymes and myocardial Ang Ⅱ were much lower in APS group, while levels of insulin, C-peptide and plasma Ang Ⅱ were the same. Levels of expression of collagen Ⅰ and the ratio of collagen Ⅰ/collagen Ⅲ in APS group were lower than those in DM group. APS group showed lower levels of chymase mRNA expression and activity than those in DM control group, while there was no diference in ACE mRNA expression and activity between the two groups.

结果 APS组血糖、糖化血清蛋白、心肌酶谱和心肌Ang Ⅱ水平较DM组显著下降，胰岛素、C肽、血浆AngⅡ水平和DM组无差异；APS组心肌Ⅰ型胶原表达和Ⅰ/Ⅲ型胶原比值较DM组显著下降；APS组chymase mRNA表达和活性均显著低于DM组，ACE基因的表达和活性与DM组无显著性差异。

It could restrain expression of collagen mRNA, suppress synthesis of collagenic in the level of gene.

抑制胶原mRNA的表达，从基因水平抑制胶原的合成。

3 The effects of APS and AstragalosideⅣon synthesis of collagen Measure the Radix Astragali impact on NIH3T3 cells collagenic synthesis of many candies with the hydroxyproline reagent box.

2.3黄芪多糖和黄芪甲苷对胶原合成的影响本实验以NIH3T3为细胞模型，用羟脯氨酸试剂盒测量黄芪多糖对NIH3T3细胞胶原合成作用的影响。

Aneurysm group: The aneurysm wall was mostly or only made of collagenic fiber, but arranged loosely, unorderly, the colouration shoaled compared with the control group.

实验组：动脉瘤壁主要由胶原纤维构成，或仅由胶原纤维组成动脉瘤壁，但排列较为疏松、无规则，与对照组相比染色变浅。

This in vivo study was to examine the historical changes of implanted novel chitosan/collagen composite barrier for confirming the clinical feasibility. Four other commercial GTR membranes were chosen for comparison. Among the resorbable GTR membranes, BioMend Extend and Peri-Aid are collagen base, and GORE-TEX OSSEOQUEST is synthesized membrane, while GORE-TEX e-PTFE (Expanded polytetrafluoroethylene) is synthesized but non-resorbable. Beagle dogs were used as animal model. Buccal mucoperiosteal flaps were reflected in the bilateral mandibular premolar and molar areas. Buccal alveolar bone was reduced on 1st、2nd premolar and molar to a level 5 mm apical to the cemento-enemel junction. Root surface was denuded of periodontal ligament and cementum, and notches were placed at the bone level of each root. The tested GTR barriers were implanted in critical bone defect areas. Flaps were coronally positioned and sutured. Two beagle dogs were sacrificed each time as the designed time period after surgery. Histological and histometirc evaluation at 7 days、14 days、28 days、3 months were performed post-operatively to determine the healing response of each treatment modality.

本研究之目的在评估与工研院生医中心合作发展出可吸收性去乙醯几丁聚醣/胶原蛋白复合之组织导引再生膜片，并选择与可吸收性之BioMend Extend 及Peri-Aid 胶原蛋白膜片，和GORE-TEX OSSEOQUEST 合成高分子膜片，及不可吸收之GORE-TEX e-PTFE合成高分子膜片，等其他四种市售商品材料共同对照评估，应用8只年龄为12个月的雄性小猎犬，均分4组(分别为7天、14天、28天、3个月)，为动物活体评估模式，在实验犬之左、右下颚第一、二小臼齿及大臼齿的颊侧区制造骨缺损后，分别植入组织导引再生膜片，依实验设定时间将小猎犬牺牲，取下缺损区骨头，以光学显微镜观察量测其牙垩质再生高度与齿槽骨再生高度之变化，以探讨其组织再生模式及评估新膜片在临床应用之适用性。

Objective To discuss the application of collagen dressing in skin cosmesis,understand the compliance of the users and sum up the clinical effect. Methods Collagen dressing was used for treatment of various dermatosis patients after treatment With microscar mill,laser,photon.

目的 通过胶原蛋白贴敷料在美容皮肤科治疗护理方面的运用，总结患者对产品的依从性及临床疗效方法将胶原蛋白贴敷料运用在各型痤疮患者及微晶磨疤机、激光、光子治疗后患者的术后护理。

Since 1962, when Gross and Lapiere discovered the first MMPs-collagenase, man had discovered various of MMPs in succession, where MMP-2 has a strong degradational effect on extracellular matrix, it is secreted bymacrophage, smooth muscle cells and endothelial cells and so on.

自从 1962年 Gross和 Lapiere发现第一种基质金属蛋白酶一胶原酶以来，人类陆续发现了很多种基质金属蛋白酶，其中的MMP—2对细胞外基质具有极强的降解作用，它由巨噬细胞、平滑肌细胞以及内皮细胞等分泌，在动脉粥样硬化斑块中憎多时降解纤维帽及基底膜的胶原等基质成分，是使纤维帽变薄及加速动脉粥样硬化的重要因素之一。

Objective To study the effect of type Ⅵ collagen in the physiological and degradative processes of intervertebral disc.

腰椎间盘Ⅵ型胶原的定量分析彭新生胡有谷吕振华摘要①目的探讨Ⅵ型胶原在椎间盘的生理和退变过程中的作用。

In this context, we have reported recently that the volume of myocardial tissue occupied by perimysial and endomysial collagen was lower in hypertensive patients with HF and depressed ejection fraction, than in hypertensive patients with HF and preserved ejection fraction and normotensive subjects.56 Of interest, the interstitial and perivascular accumulation of collagen fibres was abnormally high in the two groups of patients.

在这种情况下，我们已经说了占用体积perimysial心肌组织人肌内膜胶原水平低的高血压患者用高频和沮丧的射血分数在高血压患者的心力衰竭和保存被罚出场分数与正常血压subjects.56舒张压的利息、间质和血管堆积过高的胶原纤维是在两组病人。

And Pharaoh spoke to Joseph, saying, Your father and your brothers have come to you.

47：5 法老对约瑟说，你父亲和你弟兄们到你这里来了。

Additionally, the approximate flattening of surface strip using lines linking midpoints on perpendicular lines between geodesic curves and the unconditional extreme value method are discussed.

提出了用测地线方程、曲面上两点间短程线来计算膜结构曲面测地线的方法，同时，采用测地线间垂线的中点连线和用无约束极值法进行空间条状曲面近似展开的分析。