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胶原

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aim to study the efficaciousness of wuling cap-sules for hepatic fibrosis in rats.methods rat models with hepatic fibrosis were induced by ccl4 compound factors and then treated with wuling capsules.pathology of liver sections,hyaluronic acid and procollagencontents in rat liver and serum were examined respectively.results pathological examinations showed that the liver cells of mod-el rats were injured seriously.collagen fibers proliferated and dissected hepatic lobules in model rats.wuling capsules could protect liver cells and reduce degrees of hepatic fibro-sis.the best effects were achieved at3.0g?

目的 研究五灵胶囊对大鼠肝纤维化的作用。方法采用以四氯化碳为主的复合因素致大鼠肝纤维化,观察五灵胶囊对肝组织病理学、肝组织和血清中羟脯氨酸、ⅰ,ⅲ型前胶原含量的影响。结果病理学检查显示,模型组大鼠肝细胞损伤严重,胶原纤维大量增生,形成假小叶。五灵胶囊组大鼠肝细胞结构破坏不明显,肝纤维化程度轻,在3.0g?kg-1 时治疗效果最好。

Gelatin, as a denaturalized product of collagen, comes from animal bone, tendon, cartilage, epimysium and hide.

明胶来源于动物骨、腱、软骨、皮肤、肌膜等结缔组织中的胶原蛋白,是胶原高级结构不可逆断裂后的主要产物。

After 14 weeks of operation, the structure of epineurium was in integrity and there was no obvious difference in perineurium and endonurium between two groups.

结果 术后 2周,A组炎性反应稍重于 B组;至 4周时两组的炎性反应程度相似,近端少许胶原纤维增生;8周时两组的炎性反应基本停止,胶原纤维增生稍明显;14周时两组神经外膜构成完整,束膜、内膜结构无明显差异。

Results In control group,three weeks after the epithelization of the wound,the thickness of the hypertrophic tissue was 3-4 times of ventro ear skin. Under microscope,the dermis was hyperplasia and got thicker,consisted with amount of fibroblast cells,collagen and vessels,the collagen was untidy,nodule or vortex,and the cartilage could be observed in some region.

结果:对照组兔耳创面上皮化后3周时,增生厚度为兔耳腹侧皮肤全层厚度的3~4倍,镜下可见真皮组织明显增生、变厚,由大量成纤维细胞、胶原组织及血管组成,胶原排列不整齐,呈结节或旋涡状分布,部分可见对应处软骨细胞增生。

DATA SYNTHESIS: Il-17 exerted the biological function after combines with its receptor maybe induced the occurrence and the development of the osteoarthritis by the way of increasing the chondrocyte, expression of inducible nitricoxide synthase and nitrogen monoxide, boosting up the tbe chondrocyte and the expression of MMP-1/3/13, boosting up the activation of the aggrecanase and the collagenase, boosting the decompose of the cartilage proteoglycan and collagen, boosting up the monocyte evocable breakage of the cartilaginous matrix.

资料综合:白细胞介素17通过与其受体结合发挥生物学作用,其可能通过增加关节软骨细胞诱导性一氧化氮合酶表达和一氧化氮产量,增强软骨细胞基质金属蛋白酶(MMP-1/3/13)的表达,增强蛋白聚糖酶和胶原酶活性,促进软骨蛋白多糖及胶原降解,并增强单核细胞对软骨基质的破坏,从而诱导和加速骨关节炎的发生和发展。

METHODS: Human umbilical cords were processes within 6 hours with explantation technique, collagenase digestion and enzymes combination digestion after harvested, and followed by counted colony numbers. A colony contains more than 50 cells.

脐带采集后在6 h内分别用植块法、胶原酶消化法、胶原酶与胰酶联合消化法进行分离培养,于培养第14天计数集落数,超过50个细胞计为集落。

The corium is under the epidermis, it's made up of connective tissue that contains collagenous fiber, elastic fiber, reticular fiber and ground substance between fasciculus, it's very important for the elasticity and lusty of the skin, malnutrition, ageing and long-time excessive exposure to the sun would all lead to wrinkles and sagging of the skin, the reason of this is denature or fracture of collagenous fiber and elastic fiber.

真皮在表皮之下,由胶原纤维、弹力纤维和网状纤维组成的结缔组织,与纤维束间的无定形基质构成,对皮肤的弹性光泽和弹力等有着重要作用,营养不良、衰老或长期过度日晒会使皮肤发生皱纹、弹性松弛,是胶原纤维及弹力纤维变性或断裂的结果。

Our Collagen is porcine Collagen comes from DaYi zoology hoggery, The same collagen as the injections except processed differently.

我们的胶原蛋白来源于猪,来自大邑生态养殖区,我们的注射胶原蛋白也是一样,只是加工工艺不同。

To observe the inhibition action of human/rat homology collagen type I siRNA on human TGF-β1-induced expression of collagen type I.

目的 观察人鼠同源I型胶原siRNA抑制TGF-β1诱导的Ⅰ型胶原高表达的有效性。

398 Neutral protease applied in technology for preparation of gelatin hydrolyzate was discussed.

水解明胶亦称胶原多肽,是胶原蛋白或明胶经过一定的降解而得到的多肽混合物。

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