胶

SEM result showed that the sample had uniform phase distribution and smooth surface at dried state as well as interpenetrate network structure at hydrogel state. It was seen from the swell ing behavior curves that groups T1, T2 and T3 swelled rapidly within 10-30 minutes, and formed elastic composite hydrogel pipes. In addition, the expanding ratio of inner and outer diameter of the tube was 20%-30% and 100%-120% with swell ing, respectively. The equil ibrium water content of the hydrogel pipes increased with increase of collagen composition. Three groups of samples were immerged in PBS solution contained 2 mg/mL lysozyme at 37 for 1 month, their nozzle cracked, their wall became thin and more transparent. And also, there was small floc deposited on the tube surface.

扫描电镜观察到液氮脆断的人工泪小管内部成分分布均匀，内外壁表面平整，冷冻干燥的人工泪小管断口呈凝胶态的互穿网络结构。3 组不同成分的人工泪小管在PBS 溶液中浸泡30 min 后均快速吸水溶胀，外径扩大100%～ 120%，内径扩大20%～ 30%，并且随胶原含量增高，溶胀速度增快，平衡溶胀率增大。3 组人工泪小管在37℃含2 mg/mL 溶菌酶的PBS 液中浸泡1 个月后，表面有部分细小絮状物，管口开裂，管壁变薄，透明度增加。

PARTⅡCharacteristic of MMP-9 Activation in Microglia and itsCytokines Secretion after HSV-1 infectedObjective: To investigate the characteristic of MMP-9 activation in microglia and itscytokines secretion.Methods: Balb/c mice were injected intracerebrally with herpes simplex virus type 1(HSV-1) to form herpes simplex encephalitis.

第二部分HSV-1感染小胶质细胞后MMP-9及炎性因子分泌特点研究目的：研究单纯疱疹病毒(HSV-1)感染小胶质细胞系BV2后炎性因子的表达特点，探讨BV2细胞可否作为小鼠单纯疱疹病毒性脑炎模型的替代研究对象。

Objective Effects of collagen degradation in hypertrophic scar by intradermal injection of collagenase were observed.

目的 观察胶原酶对肥厚性瘢痕胶原降解的影响，探讨它对HTS的治疗作用。

Methods Twenty DBA/1 mice were divided randomly into model group and control group with 10 in each, the model group were injected intradermally at the root of the tail with 100 μl emusion containing an equal volume of bovine type Ⅱcollagen solution and complete Freund's adjuvant on the 1st and 21 day. The control group were given 100 μl emusion containing an equal volume of complete Freund's adjuvant and glacial acetic acid.

取20只DBA/1小鼠随机分为模型组和对照组各10只，模型组分别于第1、21天自尾根部取3点皮内注射牛Ⅱ型胶原与褔氏完全佐剂充分乳化的胶原乳剂100μl，对照组同上方法注射褔氏完全佐剂与0.1M冰醋酸等体积乳化液100μl。

Appraised the clinical effect of the flavone of rhizome drynania on Senile Osteoporosis, according to the dynamic observation on integrative scores of lumbodorsal pain and lumbodynia,"VAS section grading method" on lumbodynia,"Barthel index rating method" on ADL, detected BMD on anterior-posterior position lumbar2~4 vertebra body and proximate of femur including neck/ward/troch, and determined the index of bone transition including BGP/PINP/ICTP through the radioimmunity method before and after treated half a year, then contrast intragroup and selfgroup. Depending on the standard of curative effect, contrast the difference of curative effect between two groups.

采用随机对照的方法，分为治疗组36例，对照组34例，依据对腰背痛及腰痛综合评分进行动态观察；依据"疼痛VAS线段分级法"对腰背痛（静止痛、翻身痛、久坐痛、起身痛、弯腰痛、步行痛、睡眠痛、叩击痛、压痛）进行量化动态观察；依据"Barthel指数评定法"对老年性骨质疏松症日常生活活动能力进行观察；采用双能X线骨密度仪对腰椎(L2-L4)、股骨近端各部位：股骨颈、股骨三角区、股骨粗隆进行骨密度定量检测；应用放射免疫法对骨转换指标进行测定，骨形成指标：骨钙素、Ⅰ型前胶原氨基端前肽；骨吸收指标：Ⅰ型胶原交联羧基末端肽等，评价骨碎补总黄酮治疗老年性骨质疏松症的临床效果。

It is a type of new inverted rubber based on the technology of original 729 inverted rubber.

它是在原"729"反胶的基础上发展的一款新型反胶。

Results The tiopronin in situ gel of 0.2 % sodium hyaluronate had proper gelating temperature and certain sustained releasing ability, Papp and retention time of which was 15.43 cm·s-1 and 130 min respectively, irritancy and stability were up to standard of ophthalmic preparation.

结果 含有质量分数0.2 %透明质酸钠的硫普罗宁原位凝胶具有适宜的胶凝温度和一定的缓释作用，其角膜表观透过系数为15.43 cm·s-1，角膜前滞留时间为130 min；刺激性、稳定性符合眼用制剂要求。

Methods The formula of tiopronin in situ gel was designed and optimized by determining the gelating temperature, gel dissolving and drug releasing, transcorneal penetration in vitro, and was evaluated by investigating retention time, irritancy and stability.

以胶凝温度、凝胶溶蚀量、体外药物释放度、离体角膜透过性为考察指标，设计和优化处方；以家兔为受试动物，考察硫普罗宁在角膜的滞留时间、刺激性及稳定性。

All enhancers did not significantly change the transcorneal lag time of ENX. The irritancy of poloxamer and Azone was observed.? The results of in vitro release studies showed that the ENX gel based 3% HPMC K4M and 3%HPMC F4M povided sustained release of the drug over an 8-h period in vitro.Diffusion area has significantly effect on drug release, and pH value of medium and rotation rate have effcet on drug release.However, the diffusion shield has no effect on drug release. The P_ value of the preparation based on 3% HPMC F4M was 1.34-fold of conventional eye drops of ENX.

体外溶出度试验结果表明，以3％的HPMC K4M和F4M为基质制备的ENX凝胶剂的体外释放行为符合眼用缓释制剂的要求；体外释放度影响因素试验结果表明，释放面积对释放度有显著性影响，pH值和转速略有影响，而扩散屏障没有影响；离体角膜透过实验结果表明，以F4M为基质制备的凝胶剂中ENX的表观渗透系数P_(app是对照组的1.34倍，说明F4M与眼角膜的相容性较好，是一种理想的眼用制剂增稠剂，可以在眼用制剂中广泛采用。

The synthetic technology of moisture curing isocyanate adhesive and adhesive technology .bonding mechanism for high moisture content wood were studied in this paper.

本论文对用湿固化异氰酸酯胶粘剂的合成工艺、湿固化异氰酸酯胶粘剂与高含水率木材的胶接工艺以及高含水率木材的胶接机理进行了研究。

Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时，他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

实际上 我们已接通卫星可视电话了