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RESULTS: Transection of the tibial and sural nerves inducedcold allodynia and moderate mechanical hyperalgesia.

结果:胫神经和腓肠神经的横断导致异常性冷疼痛和中等强度的机械性痛觉过敏。

It has been well documented that the fibular collateral ligament is the primary varus stabilizer of the knee.8,10 Consequently, isolated FCL injuries can elicit abnormal varus knee instability that can lead to functional limitations, a varus thrust gait pattern, and the potential development of medial meniscal tears or medial compartment arthritis over time due to the increased compressive forces at the medial tibiofemoral compartment.16,23,30 In addition, it has been demonstrated that varus instability, primarily due to a deficient FCL from an untreated posterolateral knee injury, causes a significant increase in force on both anterior cruciate and posterior cruciate ligament reconstruction grafts.11,21,22 Therefore, a reconstruction technique to address nonrepairable acute or chronic isolated FCL tears is important to address these pathologic abnormalities.

已经证实腓侧副韧带是防止膝关节内翻的主要稳定结构[8,10]。因此,FCL离断伤可以引起异常的膝关节内翻不稳定,从而导致功能受限、膝内摆步态和潜在发展为内侧半月板撕裂或由于在增加胫股关节间隙的压力会随时间推移发生内侧间室关节炎[16, 23, 30]。此外,已经证实了主要由膝关节后外侧损伤后未经治疗导致FCL功能缺陷引起的膝内翻不稳可以引起前交叉韧带和后交叉韧带重建移植物受力明显[11,21,22]。因此,认为不可修复的急性或慢性FCL离断撕裂伤的重建技术对这些病理异常非常重要。

Results The fibular proper plantar arteries and nerves longitudinal and transversal sectional average diameters were longer then 0.43mm and 0.65mm respectively. Those of the tibial proper plantar arteries and nerves longitudinal and transversal sectional average diameters were 0.55mm and 0.58mm respectively.

结果 趾跖腓侧固有动脉和神经纵径和横径的平均值分别大于0.43 mm和0.65 mm,趾跖胫侧固有动脉和神经纵径和横径的平均值分别为0.55 mm和0.58 mm。

The changes of wet weight, crosssectional area, total protein, and ultrastructure of the denervated muscle were detected.

另取Swiss小鼠30只,同样方法切断其胫神经后,连续腹腔注射CT-1(100μg/kg/d),于7、14和28d后检测失神经腓肠肌的湿重、肌纤维横截面积和肌肉总蛋白含量,观察超微结构的变化,分别与对照组比较。

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