胡椒碱

Objective To observe the effect of piperine on experimental gallstone formation in the gallbladder of C57BL/6 mice.

目的观察胡椒碱对实验性C57BL／6小鼠胆囊结石形成的影响。

Treated with high concentration of piperine （0.56 mmol/L） for 24 hours and 48 hours respectively, following a period of growth retardation, the cells of 24-hour-group could recover slowly while the 48-hour-group showed inconvertibility.

由此认为：胡椒碱对C6/36细胞株有毒性作用，但药物诱导的细胞凋亡在细胞毒性作用机制中不占主导地位；胡椒碱对C6/36细胞的作用有时间依赖性，延长作用时间，药物对细胞的毒性作用增强。

MethodsWith the extract yield and piperyl piperidine content as index, orthogonal test was used to evaluate the influence factors, including the concentration of alcohol, the extracting time and the amount of alcohol.

方法采用正交实验法，以固含量和胡椒碱含量为考察指标，对乙醇浓度、回流次数、乙醇用量等影响因素进行研究。

AIM: To study the effects of piperine on several experimental gastric ulcers in rats and mice.

目的：研究胡椒碱抗大鼠或小鼠实验性胃溃疡的作用。

MethodsThe content of piperine in extract was determined by HPLC.

目前胡椒中含量及活性最高的胡椒碱的提取方法主要是有机溶剂提取法［3］。

Microwave vacuum distillation and ethanol as solvent are used to extract pepper oil and piperine from black pepper in this research.

采用微波减压蒸馏及乙醇提取法对胡椒油和胡椒碱的提取进行了研究。

Piperine is a kind of alkaloid extracted and refined from pepper fruit utilizing modern biological engineering high technology.

胡椒碱是运用现代生物工程高新技术，由胡椒科植物胡椒果实中提取精制而成的一种植物类生成碱。

Based on this,a sensitive method has been developed for the quantitative determination of piperine in Mn-piperine-cetyltrimethylammonium bromide ternary system.

据此建立了在锰-胡椒碱-溴化十六烷基三甲基胺三元体系中测定胡椒碱的荧光分析新方法。

Piperate and methyl piperate exhibited a good protecting effect on cardiac myocytes while uridine had not activity.

对H202诱导的心肌细胞损伤，胡椒酸甲酯和胡椒碱具有明显的保护作用，咖啡酸甲酯具有部分保护作用，尿嘧啶苷无保护作用。

Objective To further vertify the bioactivities and mechanism of piperine and to investigate the effect of piperine on the ion channel of insect cytes, the toxicity and lethal effect of piperine against Culex pipiens pallens larvae and Spodoptera frugiperda cell line were investigated under the laboratory conditions.

目的研究胡椒碱对淡色库蚊幼虫和草地贪夜蛾 Sf-21细胞的毒力作用和后致死作用，进一步揭示胡椒碱的作用机制及作用方式，以便进一步研究其对昆虫细胞离子通道的影响。

The basic concept of FOP can be summarized as to further optimize effective prescription according to the standard of curative effects and with the aid of modern science and technology and theories of traditional Chinese medicine.

其基本内涵可概括为：以确有疗效的中药复方为研究对象，以现代科学技术和传统中医药理论为技术支持，以该复方所治病证的药效响应为评价标准，以优化重组疗效更优的新复方为研究目的。

Ever since our world has been a world, native forests have been indiscriminately exploited by man.

自从我们的世界一直是世界原生森林被任意剥削人。