胞质

N IND sections, the picture of dysplasia neurons can be distinguished from the normal easily with a smaller cell and cytoblast diameter, a distinct increase of number, less and stain thickened cytoplasm, nucleolus exit or not.

ND病变肠段粘膜下及肌间均有巨神经丛，丛内各成分细胞均呈阳性反应，神经丛内有大量大小不等细胞，为胶质细胞与发育不良神经元，其中可见部分细胞胞体较大。

Figure5 HE 10×10 The tumor cells are large and have rich cytolymph, red coloration. The nucleolus is round or elliptical shape.

图5 HE10×10 肿瘤细胞较大，胞浆丰富，红染，核圆或椭圆形，染色质细，核仁及核膜清楚，背景可见较多成熟淋巴细胞、嗜酸粒细胞，散在巨噬细胞。

The comprehensive evalucation resulted in a strong drought resistance group including ZXY04P-201、ZXY03P-227、ZXY03P-122 and ZX Y04P-136, a weak drought resistance group including ZXY04P-101、ZXY04P-89,ZXY04P-239 and a intermediate group including the others according to the the above indicators. 3. The results of study on drought mechanism for 4 Dactylis glomerata L. under continuously water stress and rewatering show: the water saturation deficit of leaves arose hastily, and ZXY04P-239 changed most obviously while ZXY04P-201 changed only slightly under drought stress. ZXY03P-173 and ZXY04P-201 increased in the relative plasmalemma permeability and the soluble sugar content while thant of ZXY04P-75 and ZXY04P-239 showed the trend of initial increasing, reaching the peak at the 8th day, then decreasing under drought stress.

20份鸭茅种质幼苗期抗旱性研究表明，干旱胁迫条件下，所有材料的株高、生物量显著下降，叶片脯氨酸和可溶性糖作为重要的渗透调节物质，其含量迅速增加，质膜相对透性的数值变大，细胞膜受伤害程度增大，水分饱和亏缺值变大，植物保水能力变弱，胞间CO2浓度增大；净光合速率、蒸腾速率、气孔导度和叶绿素含量等指标测定值减小，通过20份鸭茅种质苗期抗旱性综合评价，发现ZXY04P-201、ZXY03P-227、ZXY03P-122、ZXY04P-136属强抗旱性材料，ZXY04P-101、ZXY04P-89、ZXY04P-239属弱抗旱性材料，其他属于中等抗旱性材料。

Results①The Rab9 and NPC1 colocalized in cytoplasm of microglia.②Rab9 expressed in lysosome,Golgi apparatus and late endosome.

结果Rab9和NPC1共定位于小胶质细胞胞浆内，Rab9表达于溶酶体、高尔基体和晚期内体。

The mice inoculated with Coxiella burnetii intrana- sally developed interstitial pneumonia,while the primary pathological changes of mice inoculated intraperitoneally are granulomas in spleen and liver.2.The pathological changes became more severe followed the dosage increasing.3.Coxiella burnetii can be detected in spleen and liver at day 2 after inoculation.the lesion became more and more serious from day 2 to day 12.The characteristic changes were observed at day 7,and recovered at day 14. 4.The reticuloendothelial system are main target of Coxiella burnetii.The pathogen was detected in cytoplasm of monocyte -macrophages of spleen, liver, lung, and endothelioid cells of blood vessel. 5. Coxiella burnetii can be found in macrophages lysosomes by electron microscopy. Most of them are round or rod, and polymorphic shape can also be observed in different size.

结果：1、通过不同感染途径的实验证实，滴鼻感染的小鼠主要表现为间质性肺炎，而腹腔注射感染小鼠则以脾脏、肝脏肉芽肿为主要病变。2、通过不同剂量的感染实验发现，随着感染Q热立克次体剂量的加大，动物病变愈加严重。3、通过感染后不同时间的动态病理学观察发现，在腹腔注射后第2d的脾和肝脏即可发现病原体，主要脏器的病理变化从第2d到第12d逐渐加重，第7d动物的病变最典型，至感染后14d动物的受损器官已开始出现修复性变化。4、 Q热立克次体主要侵害机体的网状内皮系统，在感染小鼠的肝、脾、肺和外周血管单核巨噬细胞以及血管内皮细胞胞浆中查见病原体。5、透射电镜观察可见Q热立克次体主要位于巨噬细胞吞噬溶酶体内，呈多形性，多见圆形和杆状，大小不一。

To regulate tumor cells proliferation and metastasis. In many malignant tumors, CD44 has shed by MT1-MMP extracellularly, and causes the release of the soluble CD44, which facilitate the tumor cells motility.

在多种恶性肿瘤中，CD44分子胞外结构域可被膜结合型基质金属蛋白酶1(MT1-MMP)剪切，导致&可溶性&CD44分子的释放，此过程在细胞迁移中发挥重要作用。

Experimental data were acquired by LabVIEW and processed through the time-domain analysis and frequency-domain analysis with Matlab. We analyzed qualitatively the specific effect of different tastants and proved the sensitivity to salt and sourness of taste receptor cells isolated from rat fungiform papilla. These experimental results demonstrate the feasibility that the cell chip based on LAPS can be used in the study of taste transduction mechanism.

采用LabVIEW采集数据、Matlab进行时域和频域分析，我们定性分析了不同味质作用于味觉细胞后胞外电信号的变化，证实了大鼠菌状乳头的味觉细胞对于咸味和酸味的敏感性，实现了细胞芯片在味觉传导机理研究中的应用。

Drug sensitive test and three-dimensional test220 strains of Pa were isolated from hospitalized patients between 2003 and 2007. K-B method was used to tested the susceptibility of 10 different antibiotics. IRPa was screened by testing the minimal inhibitory concentration of imipemem by using agar diluiion method.The susceptibility of these IRPa to the antibiotics was analysised. Three-dimensional test was used to identify the different kinds of beta lactamases from 220 strains of Pa.2.Carbarpenems hydrolytic enzyme genes and oprD2 gene were detectedamong the selected IRPa strains, PCR method was performed to detect carbapenemase genes which included GES、KPC、SPM、VIM、IMP、GIM gene and the oprD2 gene;Multiplex PCR were used to detect OXA genes and plasmid-mediated AmpC beta lactamase genes; The expression of the chromosomal AmpC beta lactamases and oprD2 genes in IRPa strains were analyzed by Real-time PCR.3.Identification and characterization of integronsIntegrase gene was detected by PCR, and the classification of integrons was performed by using restriction fragment length polymorphism.PCR was performed to detect the qacE△1-sull gene,and the gene cassetes which are located at variable region of integrons in the strains were detected to be positive.

方法1、药敏实验和三维实验收集2003～2007年临床分离的220株Pa，对这些菌株采用K-B法测定10种临床常用抗生素的药敏情况，同时采用琼脂稀释法检测亚胺培南的最低抑菌浓度(Minimal inhibitory concentration，MIC)，筛选出对亚胺培南耐药的铜绿假单胞菌，并分析其对其它抗生素的药物敏感率；采用三维实验的方法分析220株Pa产β内酰胺酶的类型。2、碳青霉烯类水解酶和oprD2蛋白的检测针对鉴定的IRPa菌株，采用普通PCR方法检测具有碳青霉烯水解作用的β内酰胺酶耐药基因(GES、KPC、SPM、VIM、IMP、GIM基因)和oprD2基因，采用多重PCR的方法检测OXA型基因和质粒携带的AmpC酶基因，用荧光定量RT-PCR方法检测oprD2蛋白基因表达情况；同时对产AmpC酶的Pa(25株，含IMP耐药和敏感株)用RT-PCR方法检测AmpC酶基因的表达量情况。3。

Organelle and biological molecular;the method to show the nucleic acid、protein、enzyme、glucide and lipid;microspectrophotometry and flow cytometry.

胞内核酸、蛋白质、酶、糖类与脂质等的显示方法；显微分光光度测定技术和流式细胞仪

objective: the purpose of this study was to investigate the role of turkish gall extract on the metabolism of glycose metabolism and acid metabolism of cariogenic bacteria and to find out the mechanism of anticariogenic of turkish gall.

目的：研究没食子鞣质及其提取物对致龋菌产酸及产水不溶性胞外多糖能力的影响，探讨实验药物的防龋机制。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。