胞浆素

The pathologic phenotype in all cases has thus far included ubiquitinated neuronal intranuclear inclusions and neuronal cytoplasmic inclusions.

其病理表现包括泛素化的神经元的核内包涵体和神经元的胞浆包涵体。

The results showed that,on first day induced by mIL-2+B16,mIL-2+B16PELs had no cytotoxicity to B16 target cells,no expression ofperforin and granzymeA genes,no granules in PELs cytoplasm.

结果显示：1.mIL-2〓细胞诱导一天时，取得的PEL用Rt-PCR检测，无粒酶A与穿孔素基因表达、无细胞毒活性、其胞浆中也无杀伤颗粒存在。

Hwoever,on third and fifth induced day,mIL-2+B16 PELs and 22.8% and 23.1%cytotoxicity,distinct expression of perforin and granzymeA genes,many granules in cytoplasm.

在这一天〓细胞诱导的PEL与上述结果相同。2.mIL-2〓细胞诱导三天时，取得的PEL则有明显的粒酶A和穿孔素基因表达，其细胞毒活性也达22.8%，电镜下的PEL胞浆中可观察到杀伤颗粒。

In addition, a metabolic inhibitor, actinomycin D has no effect on enzymatic activities of caspase-1/ICE-like and caspase-3/CPP-32/like proteases during Fas-mediated CD4〓T cell apoptosis. These results indicate that the appearance of caspase-1/ICE-like and caspase-3/CPP32-1ike proteases activities is a post-translational activation of these proteases. It is likely these caspases constituently express in a inactive form in the cytosol of CD4〓T lymphocytes. Once the rest SEB-responsive CD4〓T cells are restimulted, those inactive caspases such as caspase-1/ICE-like and caspase-3/CPP32-1ike proteases are sequentially cleaved to become active forms, and the apoptotic signal is transducted to downstream signaling molecules, Finally leads to CD4〓T cells apoptosis.

另外，通过代谢抑制剂放线菌素D对超抗原SEB诱导静息SEB应答〓细胞凋亡过程中Caspase成员酶活性变化的研究表明Caspase-1／ICE样，Caspase-3／CPP32样胱氨蛋白酶并非新合成的信号分子，很可能以无活性方式组成性表达于静息SEB应答〓细胞胞浆，在超抗原SEB再次刺激诱导〓细胞凋亡早期，先后顺序活化，借以传递凋亡信号到下游信号分子，诱导〓细胞凋亡。

The infection of chlamydia trachomatis and ureal mycoplasma may be one of the factors, which cause the erosion of cervix.

沙眼衣原体和解脲支原体是引起宫颈糜烂的一种因素，宫颈糜烂合并 CT或 uu感染者治疗上应加用影响胞浆蛋白质合成的抗生素药物如阿奇霉素

Positive staining of oxytocin and vasopressin were in the cytosol of the neurons and the former gave less intensity,many positive varicosities for vasopressin were also noticed in neurite.

催产素的免疫阳性产物主要在细胞核周围的胞浆即核周质内，而加压素的免疫阳性物质除了在核周质内有很强的反应外，在突起内也可见很强的免疫反应。

METHODS: The presence and number of recently developed extra-articular manifestations and a weighted EAM score, as well as the levels of serological markers, were compared between 31 patients with RA with histologically proven vasculitis and 50 patients with RA in whom vasculitis could not be documented histologically. The following markers were evaluated: circulating immune complexes, complement components C3 and C4, class-specific rheumatoid factors, antineutrophil cytoplasmic antibodies, antinuclear antibodies, antiendothelial antibodies, circulating intercellular adhesion molecule-1 and -3, circulating vascular cell adhesion molecule and E-selectin, cellular fibronectin, von Willebrand factor antigen, and C reactive protein.

对比组织学上已证实有血管炎的31例 RA 例和组织学上无血管炎的50例 RA 患者间的临床及血清学标记物，这些资料包括最近发生的关节外表现数量、关节外表现加权得分、循环免疫复合物、补体 C3和 C4、类风湿因子（ IgM-RF，IgG-RF，IgA-RF ）、抗中性粒细胞胞浆抗体、抗内皮细胞抗体、循环细胞间粘附分子-1和-3、循环血管内皮粘附分子和 E-选择素、细胞纤连蛋白、假性血友病因子抗原（ von Willebrand factor antigen ）及 C-反应蛋白。

The expression of these two integrins was stronger and longer in every layer of detached retina than in reattached retina.

视网膜脱离后，这两种整合素在视网膜各层细胞表达均增强，在Müller细胞胞浆中表达增强尤为明显。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！