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胞浆

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The activities of succinate dehydrogenase in hepatocytes, alkaline phosphatase and thiamine pyrophosphatase on the wall of bile canaliculi became obviously less.Both the activities and localizations of TPPase had changed. Some TPPase from the damaged lysosome-like vesicles and Golgi saccules of hepatocytes discharged into the cytoplasm. TPPase reaction product in some bile canaliculi decreased.

酶细胞化学技术显示肝细胞线粒体琥珀酸脱氢酶和毛细胆管壁上的碱性磷酸酶活性明显减弱或消失,焦磷酸硫胺素酶的活性及定位也发生了改变, TPPase从损伤的高尔基复合体及溶酶体样小泡漏出进入胞浆,部分毛细胆管壁上的TPPase反应物减少。

In addition, a metabolic inhibitor, actinomycin D has no effect on enzymatic activities of caspase-1/ICE-like and caspase-3/CPP-32/like proteases during Fas-mediated CD4〓T cell apoptosis. These results indicate that the appearance of caspase-1/ICE-like and caspase-3/CPP32-1ike proteases activities is a post-translational activation of these proteases. It is likely these caspases constituently express in a inactive form in the cytosol of CD4〓T lymphocytes. Once the rest SEB-responsive CD4〓T cells are restimulted, those inactive caspases such as caspase-1/ICE-like and caspase-3/CPP32-1ike proteases are sequentially cleaved to become active forms, and the apoptotic signal is transducted to downstream signaling molecules, Finally leads to CD4〓T cells apoptosis.

另外,通过代谢抑制剂放线菌素D对超抗原SEB诱导静息SEB应答〓细胞凋亡过程中Caspase成员酶活性变化的研究表明Caspase-1/ICE样,Caspase-3/CPP32样胱氨蛋白酶并非新合成的信号分子,很可能以无活性方式组成性表达于静息SEB应答〓细胞胞浆,在超抗原SEB再次刺激诱导〓细胞凋亡早期,先后顺序活化,借以传递凋亡信号到下游信号分子,诱导〓细胞凋亡。

Objectives To study the clinical and pathological features of patients with ANCA-negative pauci-immune crescentic glomerulonephritis.

目的 了解抗中性粒细胞胞浆抗体阴性的少免疫沉积型新月体肾炎的临床病理特点。

A novel class of autoantigens of anti-neutrophil cytoplasmic antibodies in necrotizing and crescentic glomerulonephritis: the lysosomal membrane glycoprotein h-lamp-2 in neutrophil granulocytes and a related membrane protein in glomerular endothelial cells.

PMID 7836914一种新型的类自身的抗中性粒细胞胞浆抗体和细胞坏死性新月体肾炎:在溶酶体膜糖蛋白氢灯- 2的中性粒细胞和相关的膜蛋白在肾小球内皮细胞。

The type of cell death caused by ricin was related to the ricin concentration and time of incubation with HeLa cells. The typical apoptosis was induced by ricin 0.05μmol〓. The apoptotic cells mainly showed cell shrinkage, cytoplasmic membrane blebbing, the chromatin condensation and fragmentation, crescentic nuclear and membrane bound apoptotic bodies formation.

细胞死亡方式也与蓖麻毒素作用时间和浓度相关,0.05μmol.L〓的蓖麻毒素可引起HeLa细胞发生典型的细胞凋亡,主要特征是细胞体积缩小,胞浆起泡,细胞核染色质浓缩、凝集,新月状核和膜包裹核染色质的凋亡小体形成。

Microscopically, these tumors are composed of tubules and variably sized cysts lined by cuboidal and columnar cells with eosinophilic cytoplasm.

显微镜下,这些肿瘤由小管和由含有嗜酸性胞浆的立方和柱状细胞围成的不同大小的囊腔所组成。

The immunohistochemistry study confirms that the expression of CTGF is mainly in fibroblast cytolymph of dermis.

免疫组化研究显示CTGF主要定位于真皮层成纤维细胞胞浆中。

Results ADSCs, transfected by lentivirus, can differentiate into neuron-like cells and express NSE in cytolymph.

结果 慢病毒转染ADSCs形态类似神经元,胞浆神经元特异性烯醇化酶表达阳性。

The effects of situ hybirdization study show that the expression of NO-i increases evidently in the cytolymph of bone. It proves that GSL can obviously increase the content of NO-i and promote the synthesis of bone and secretion of iNOS.

组化及原位杂交研究结果显示,在软骨细胞的胞浆中,NO合成酶的表达显著增加,表明骨疏灵能明显增加NO合成酶的含量,并能促进成骨细胞合成和分泌NO合成酶。

Results ADSCs, transfected by lentivirus, can differentiate into neuronlike cells and express NSE in cytolymph.

结果 慢病毒转染ADSCs形态类似神经元,胞浆神经元特异性烯醇化酶表达阳性。

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