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胎盘形成

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On the morphological differentiation,by inducing of fetal calf serum,it wasshown that the cytotrophoblast cells underwent aggregation first,and the adjacentcytoplasm membranes became tightly contacted through desomosomes andcytoskeleton.Then the adjacent cytoplasm membranes disintegrated fragmentallyto form fusion pore-like structure.Finally the multinuclear cells formed and inwhich the intercellular desmosomes disappeared.Immunocytochemical stainingfurther demonstrated that the formation of syncytium was through cell membranefusion rather than the amitosis process.

细胞形态分化的研究结果表明:早孕胎盘来源的细胞滋养层细胞在血清诱导下,首先发生聚集,并通过桥粒和细胞骨架使相邻的细胞膜紧密接触;之后细胞膜发生片段断裂,形成融合孔样结构;细胞间桥粒消失,最终形成多核的合体细胞;免疫细胞化学分析进一步证实合体化是通过细胞膜融合而非无丝分裂(amitosis即细胞核分裂而细胞质不分裂)实现的。

After the formation of the placenta, the human body can produce an endocrine called human chorionic gonadotropin ...

胎盘形成后,人体内便产生一种内分泌叫绒毛膜促性腺。。。

Objective: TO explore the molecular mechanism of the components of milkvitch-red sage compound elevating placenta blood supply from the point of view of invading by nutrient cells languishment, formation of placental decidual vas net, endurance mechanism and languishment of nutrient cells.

目的:从滋养细胞侵入、胎盘蜕膜血管网络形成、妊娠免疫监视/耐受机制、滋养细胞凋亡等角度,研究探讨黄芪、丹参复方成分提高胎盘血供的分子机制;方法:分离提取黄芪,丹参有效组分(黄芪总皂甙、总黄酮;丹参提取丹参酮、丹参醌、丹参酸三部分)。

These findings support the idea that successful placentation depends on the correct balance of NK cell inhibition and activation in response to trophoblast.

这些发现支持的理念是,成功的胎盘形成取决于NK细胞在回应滋养层细胞时抑制和激活的平衡。

Pre-eclampsia and recurrent miscarriage share the pathogenesis of defective placentation and therefore we have now genotyped couples with RM.

先兆子痫和再生性流产共同导致胎盘形成缺陷,因而我们我们将它们的基因型与RM配对。

The functions of HIF during the processes of embryo implantation, placentation, embryogenesis and male reproduction in mammals will be reviewed in this article.

本文综述了HIF在哺乳动物的胚胎著床、胎盘形成、胚胎发生以及雄性生殖等过程中的作用。

These results lead us to propose that HLA-G may contribute to placentation during early and mid-term pregnancy, and participate in maintaining gestation during term pregnancy.

由此推测HLA-G在妊娠早、中期与胎盘形成有关,在妊娠晚期可能参与妊娠维持。

BACKGROUND: The natural killer cells at the site of placentation express killer-cell immunoglobulin-like receptors that can bind to human leukocyte antigen-C molecules on trophoblast cells.

背景:自然杀伤细胞在胎盘形成时表达伤细胞免疫球蛋白样受体,它可以在滋养层细胞上与人白细胞抗原-C分子结合。

The NO content and the NOS activity were down in the PIH pregnant women placenta.This showed that the ghrelin regulated the VEGF and influenced the the NO down.And the placenta angiospasm,blood pressure highten, and the PIH were caused also by this. The ghrelin,VEGF,Flt-1,NO and NOS were detected by the SP-immunochemistry, RQ-PCR,cell culture in vitro,ASODN and nitrate reductase in the normal pregnancy,PIH placenta and the cultured HUVEC antisense blocking ghrelin in vitro.

结果证实:PIH孕妇胎盘组织中Ghrelin,VEGF、Flt-1蛋白和mRNA水平下降与正常孕妇比较有显著性差异p<0.05提示在PIH发病过程中Ghrelin可能对VEGF,Flt-1蛋白和mRNA的表达具有下调作用,进而影响胎盘血管网的形成和发育;NO含量与NOS活力水平在PIH孕妇胎盘组织中下降,提示Ghrelin可能通过下调VEGF的表达进一步影响血管舒张因子NO水平下降,进而引起胎盘血管痉挛,血压升高,最终导致PIH的发生。

Placental factors, such as the placenta dysplasia, a smaller placenta, placental formation Duocheng lobulated, therefore, the fetus through the placenta supplies nutrients bound to be affected.

胎盘方面因素如胎盘发育不良,胎盘较小,胎盘形成多呈分叶状,因此,通过胎盘供应胎儿的营养物质必然受到影响。

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