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To examine the mucocilia of isolated tode palate and recorded the lasting time of ciliary movement with an optical microscope after application of drug solutions and take it as index to study the influence of concentration,pH and osmslarity of drug solutions on the ciliotoxicity.

用光学显微镜观察离体蟾蜍上腭纤毛在药物溶液作用下持续摆动时间,以此作为指标考查纤毛毒性受盐酸吗啉药液的浓度、溶液pH和渗透压的影响。

To examine the mucocilia of isolated tode palate and recorded the lasting timeof ciliary movement with an optical microscope after application of drug solutions andtake it as index to study the influence of concentration,pH and osmslarity of drugsolutions on the ciliotoxicity.

用光学显微镜观察离体蟾蜍上腭纤毛在药物溶液作用下持续摆动时间,以此作为指标考查纤毛毒性受盐酸吗啉药液的浓度、溶液pH和渗透压的影响。

It proved that the mutations are generally the transformation or transversion but not the insertion or deletion.

本研究得出的初步结论或推论如下: 1)经过亚硝基和PCR诱变法获得的一系列突变体在核苷酸基础上只发生了点突变,由此导致其蛋白质的序列也只是发生了个别氨基酸的突变。

3,6-Bis(1 H -1,2,3,4-tetrazol-5-yl-amino)-1,2,4,5-tetrazine was synthesized by triamino- guanidinium nitrate with 2,4-pentanedione of condensation, followed by oxidation and substitution reaction. The product was characterized by elemental analysis, IR, NMR and DSC.

以三氨基硝酸盐、戊二酮为起始原料,经缩合、氧化、取代等反应合成了3,6-双(1 H -1,2,3,4-四唑-5-氨基)-1,2,4,5-四嗪,并通过元素分析、红外、核磁、差示扫描量热法等分析手段对其进行了表征。

Objective To evaluate the effects of cyproterone acetate associated with metformin in patients with polycystic ovary syndrome unsensitive to CC.

目的 评估达英-35联合二甲双对克罗米芬不敏感型多囊卵巢综合征不孕患者的治疗作用。

And we saw there was when we look at the rosiglitozone group, it appeared to have superior to metformin and uria group with regard to myocardial infarction and stroke.

RECORD试验显示,罗格列酮减少心肌梗死和卒中优于二甲双和磺脲类。

I like pioglitazone based on the PROactive data, it is a study with some flaws but in the land of the blind the one eyed man is king so in the posse of outcome evidence we have for diabetes treatment PROactive stands with metformin as evidence based.

基于PROactive的数据我也喜欢吡格列酮这个药物,虽然这项研究有一些瑕疵,但是盲人之国,独眼称雄。在这些结果中对于糖尿病治疗PROactive赞成使用二甲双

The objective of the present study was to determine how metformin activates AMPK in endothelial cells.

本研究目的旨在明确在内皮细胞中二甲双如何激活AMPK。

Methods: in the experiment, we adopted eternalized human gastric mucosa epithelium ges1 cells transformed by nmethyln'nitronnitrosoguanidine as the model of precancerous lesions for study in vitro.

采用被n甲基n'硝基n亚硝基(nmethyln'nitronnitrosoguanidine, mnng)进一步转化后的永生化人胃黏膜上皮细胞系ges1细胞作为胃癌前病变细胞的体外研究模型;以三七水提物给彼格犬一次性灌胃,取给药前的血清、给药后2 h和6 h的血清作为实验药物血清。

Methods: The N-methyl-N-nitro-N-nitroso-guanidine transformed eternalized human gastric mucosa epithelium GES-1 cell line was used in vitro as a model of gastric precancerous lesion. The medicated canine serum was prepared by feeding to the adult Beagle dog with Radix notoginseng extracts and obtaining the serum after 2-hour medication. MC cells were cultured with medicated canine serum or non-medicated canine serum for 72 hours.

采用被N-甲基-N'-硝基-N-亚硝基(N-methyl-N'-nitroso-guanidine, MNNG)转化后的永生化人胃黏膜上皮细胞系GES-1细胞作为胃癌前病变细胞的体外研究模型,用三七提取物一次性灌胃彼格犬,取给药后2h的血清作为实验药物血清。

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