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paediatricsFrom 2007 to 2008 ,the newborn infants with high unconjugated bilirubin in our hospital was retrospectively analysed and compared with that in normal newborn.

回顾我院儿科2007-2008年住院新生儿高胆红素血症心肌酶变化并与正常新生儿心肌酶进行比较。

There are many studies concerning that the genetic variations of UGT1A1 are associated with unconjugated hyperbilirubinemia, and irinotecan-induced adverse drug reactions; however, there is no studies to investigate the association of liver injury during antituberculosis therapy and UGT1A1 genetic variations.

UGT1A1基因变异与未结合型高胆红素血症,及irinotecan诱发之药物不良反应有相关,但尚未有UGT1A1基因变异的族群,在接受抗结核药物治疗期间发生肝损伤之研究。

Methods Strains of E. coli, Pseudomonas aeruginosa and Enterococcus faecalis were added in the model biles containing diffenent concentration of unconjugated bilirubin. Observed the change of cholesterol nucleation time.

大肠杆菌、铜绿假单胞菌和粪肠球菌分别加入含有不同浓度游离胆红素的模拟胆汁中,观察胆汁中胆固醇晶体形成时间的变化。

Results: Elevated levels of unconjugated bilirubin(P.01)and Ga2+(P.05),decreased levels of total bile acid(P.01)and cholesterol(P.01)were found.

结果:乙肝病毒感染患者胆囊胆汁的非结合性胆红素、钙离子明显高于对照组(P.01,P.05),总胆汁酸、胆固醇明显低于对照组(P.01)。

Smectite Powder plusphototherapy for neonatal unconjugated hyperbilirubinemia in term neonates may decrease neonatal bilirubin levels and reduce the duration of phototherapy.

蒙脱石散剂联合光疗有助于血清胆红素水平下降,可增强光疗的疗效;缩短光疗时间,减少光疗的副作用;且不增加其他副作用。

Objective This study was to investigate the roles of TATA or G71R mutation of the undine 5'-diposphate-glucuronosyl transferase 1A1(UGT1A1) gene, A388G mutation of the organic anion transporter 2(OATP2), glucose-6-phosphate dehydrogenase(G-6-PD) deficiency to the development of neonatal hyperbiliidbinemia.

目的 探讨葡萄糖醛酸转移酶UGT1A1 TATA盒或G71R突变、有机阴离子转运因子2(OATP2)A388G突变、葡萄糖-6-磷酸脱氢酶(G-6-PD)缺乏对新生儿高胆红素血症发病的作用。

Objective Method comparison of Wako vanadate oxidation with improved J-G method for determination of bilirubin.

目的:WAKO钒酸氧化法与改良J-G法测定胆红素的方法学比较。

Objective: To investigate the changes of vasoconstrictor and vasodilator functions of isolated thoracic aorta in the rats with obstructive jaundice, so as to study the mechanism for the functional changes of the aorta in rats with obstructive jaundice.

目的:研究阻塞性黄疸大鼠离体胸主动脉收缩及舒张功能的变化规律,探讨高胆红素血症导致阻塞性黄疸大鼠离体胸主动脉收缩及舒张功能变化的可能机制。

ALT,TBIL,the indicators of the virosis of hepatitis B (HBsAg,HBeAg,HBV-DNA)were observed as quatos.

以谷丙转氨酶、血清胆红素、乙肝病毒标志物(HBsAg,HBeAg,HBV-DNA)为观察指标,比较不同治疗方案对指标的影响。

Objective:in order to compare the curative effects of using lamirudine and thymosin together with using thymosin only to the paients of chronic hepatitis b.methods:we had chosen 27 medical cases of chronic hepatitis b,which were divided into two groups:15 cases asone group,and 12 cases as the other group.let group a take 100 mglamirudine orally,qd,with half a year as a period of treatment.at the same time givethe patients injections of 100 mg thymosin,qd,for a month.to group b was only takenlamirudine.alt,tbil,the indicators of the virosis of hepatitis b (hbsag,hbeag,hbv-dna)were observed as quatos.results: at the end of the treatment, the rates that groupa and group b made hbsag transform into negative were respectively 26.67% and 16.67%(p>0.05);hbeag:33.33%,8.33%;hbv-dna:53.33%,33.33%(p>0.05).conclusion:combining thymic peptide with 3tc to treat chronic type b hepatitis, thymic peptide will not only promote b-cell to mature and transformation, but also to keep the subpopulation of t-cell in immune system in balance, which can enhance the reaction of matured t-cell to the antigen or other stimulus.

目的:比较拉米夫定(3tc)与胸腺肽联用和单用拉米夫定治疗慢性乙型肝炎的疗效。方法:选择慢性乙型肝炎患者27例,分为联合组15例和拉米夫定组12例;联合组用拉米夫定100 mg,口服,qd,疗程半年,合并用胸腺肽100 mg,静滴,qd,疗程1个月。拉米夫定组单用拉米夫定。以谷丙转氨酶、血清胆红素、乙肝病毒标志物(hbsag,hbeag,hbv-dna)为观察指标,比较不同治疗方案对指标的影响。结果:治疗结束时联合组与拉米夫定组对慢性乙肝患者血清hbsag阴转率分别是26.67%和16.67%(p>0.05);hbeag阴转率分别是33.33%和8.33%(p>0.05);hbv-dna阴转率分别是53.33%和33.33%(p>0.05)。结论:胸腺肽联合3tc治疗慢乙肝,胸腺肽具有促进t淋巴细胞的成熟和转化,并维持免疫系统各t淋巴细胞亚群间的平衡作用,能增强成熟t淋巴细胞对抗原或其他刺激的反应。

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从鲍尔点的形成原理出发,分析对称连杆曲线上鲍尔点的产生条件,提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

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