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胆红素

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Because of the small intestine when the upper part of the role of bilirubin and bilirubin, it was yellow-green; to colon when biliverdin reduced to bilirubin, and yellow.

在小肠上部时由于胆红素胆红素的作用,故呈黄绿色;到结肠时胆绿素还原成胆红素,而呈黄色。

To detect the marks reflecting the liver functions as follows:①The marks to reflect the capability to synthesize proteins, TPROT, ALB, GLB;②The marks to reflect the injury of the liver cells: AST, ALT, CHE;③The marks to reflect the capability to egest the bile, excrect, and detoxicate: TBILI, DBILI, IBILI, TBA;④The enzymes to reflect the cholestasis: GGT, ALP. Results The results of both the morphological and the pathological studies showed that the degree of the liver cirrhosis was of the terminal stage.

肝功能指标:①反映肝细胞蛋白合成代谢功能的指标:总蛋白TPROT,白蛋白ALB,球蛋白GLB;②肝细胞受损的指标;谷草转氨酶AST,谷丙转氨酶ALT,胆碱脂酶CHE;③反映肝脏胆排泄、分泌及解毒功能的指标:总胆红素TBILI,直接胆红素DBILI,间接胆红素IBILI,总胆汁酸TBA;④胆汁淤积指示酶:谷氨酰转肽酶GGT,碱性磷酸酶ALP。

Results ATP andEAA Neurotransmitter Gly were greatly increased in the bilirubin induced neurotoxicity brain; neuralcytosolic Ca2 + in the bilirubin precipitated brain tissue was significantly more than that in the controlgroup; NMDA receptor antagonist GAPA could significantly decrease the cytosolic Ca2+ overload.

结果 胆红素毒性脑组织ATP含量显著降低,细胞外Gly与细胞内Ca2+显著升高;GAPA不影响胆红素毒性脑组织ATP含量,但可显著降低细胞内Ca2+,减轻胆红素毒性脑水肿。

Objective To investigate the relationship of the deltabilirubin and deltabilirubin/total bilrubin ratio with the Cholestasis Icterus.

目的:探讨δ胆红素和δ胆红素/总胆红素比值对胆汁淤积性黄疸患者的应用价值。

The serum bilirubin, unconjugated bilirubin/albumin ratio in the two periods and the effect of different therapeutic methods on prognosis in warning period were compared.

回顾分析胆红素脑病33例临床资料,比较警告期与痉挛期的血清胆红素、间接胆红素/白蛋白比值、警告期不同治疗方法对预后的影响。

Since all the conjugated bilirubin is made into urobilinogen (and the unconjugated bilirubin cannot cross the glomerulus), bilirubin is negative on the stix

因为所有的结合胆红素是制成胆原(及未结合胆红素不能越过肾小球),所以尿胆红素是阴性的。

It may be used as a screening index of bilirubinic encephalopathy in clinics.

新生儿血清CK-BB增高与高未结合胆红素血症造成的脑细胞损害有关,CK-BB可作为临床监测高未结合胆红素血症新生儿胆红素脑病的一个筛选指标,值得临床推广。

reitman method to measure ALT and AST; bilirubin oxidase method to measure total bilirubin and conjugated bilirubin; biuret method to measure serum general protein; bromocresol purple method to measure serum albumin; enzymic colorimetric method to measure serum bile acids; benzyl aldehide azo naphthol method to measure monoamine oxide.

赖氏法。测定 ALT 和 AST;胆红素氧化酶法测定总胆红素和结合胆红素;双缩脲法测血清总蛋白;溴甲酚紫法测定血清清蛋白;酶比色法测定血清胆汁酸;苄醛偶氮萘酚法测定单氨氧化酶

The precision, linearity, anti -interference ability, recovery rate were compared among the 4 methods according to the standard method of NCCLS, and relativity between each of the 4 methods and modified diazotate J - G was calculated. Results

结果改良化学氧化法、钒酸氧化法、胆红素氧化酶法的批内精密度均小于3.0%;4种方法的回收率均在95.0%~105.0%之间;KHC3法、改良化学氧化法、钒酸氧化法和胆红素氧化酶法的线性范围分别是:0~424μmol/L、0-675μmol/L、0-629μmol/L、0-575μmol/L;胆红素氧化酶法和改良化学氧化法均有较强的抗干扰能力,和改良J-G法的测定结果有高度一致性。

Reproducibility, recovery rate, filate range, interference of haematolysis and lipaemia were evaluated by NCCLC system, and then the results were compared.

用钒酸氧化法、改良J—G法和胆红素氧化酶法测定血清中的总胆红素,按NCCLC评价方案系统评价其重复性、回收率、线形范围及溶血、脂血对胆红素测定的干扰影响,然后对测定结果进行比较。

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