胆管

Results:Comparing to the control group, the proliferation of overexpressed p16 QBC939 cells was inhibited and p16 overexpress induced G1 phase blockade.

结果：与对照组相比，p16高表达的人胆管癌细胞QBC939的增殖受到明显抑制；流式细胞光度术表明p16的高表达导致了较为明显的G1期阻滞作用，但对细胞周期的其他时相并无影响；Western免疫印迹分析结果表明癌基因c-myc的蛋白水平表达下降。

A acute partial obstructive hepatocholangitis model by selective ligation and injection of E coli into left hepatic bile duct was successfully founded in rat. Using parameters including mortality, mitochondrial glutamic oxalacetic transaminase and ornithine carbamoytransferase activity, pathological observation and blood culture of bacteria, we evaluated the model.

作者采用选择性左肝管穿刺注菌法成功地建立了Wistar大鼠急性部分肝胆管梗阻感染的脓毒症模型，并从胆管系统形态学、累计病死率、血清线粒体谷草转氨酶和鸟氨酸氨基转移酶活性、多器官大体病理观察以及血液细菌培养几方面对该模型的科学性、重复性进行了评估。

Firstly, eleven cases with empyema of the gallbladder, biliary sludge, chronic cholecystitis, polypoid cholesterolosis, papilloma of the gallbladder or pedunculated hepatocellular carcinoma were misdiagnosed as gallbladder carcinoma.

在2例伪阴性例中，1例之癌症只有胆囊粘膜上的轻微变化可见，幷只侵犯少许肌肉层，另1例则为全部胆囊壁都是癌肿瘤，且侵犯至总胆管及淋巴腺。

Objective To explore the perineural invasion of hilar cholangiocarcinoma and distribution of nerve plexuses around hepatic portal.

目的 探讨肝门部胆管癌神经浸润的方式和规律及肝门部神经丛分布的特点。

Due to the specific anatomic structure of bile duct and its close relation with peripheral nerves and various neuropeptides, perineural invasiveness and metastasis of cholangiocarcinoma are attracting more and more attention in recent years.

由于胆管的解剖部位的特点以及其与周围神经、包括多种神经肽的密切关系，其神经周围浸润转移途径近年来越来越受到人们的重视。

The most important prognostic factors for bile duct carcinoma after resection were lymph node metastasis, pancreatic infiltration and perineural infiltration.

影响胆管癌切除术后患者预后的最重要因素是淋巴结转移、胰腺浸润和神经浸润。

Methods The clinical and pathological data of 12 cases with peripapillary diverticulum treated by RouxenY reconstruction after gastrectomy were analysesd retrospectivelyResults The condition of cholangotis was gone on all patients postoperatively.

对12例采用胃部分切除胃空肠RouxenY吻合旷置十二指肠病人的临床病理资料进行分析。结果术后全部病人反复发作的胆管炎症状消失，无严重并发症。

RouxenY reconstruction after gastrectomy offers well outcome for the treatment of peripapillary duodenal diverticulum.

远端胃部分切除胃空肠RouxenY吻合旷置十二指肠是治疗十二指肠乳头旁憩室并发胆管炎有效的方法。

At 6 wk, the hepatic stem cells begin to differentiate to hepatocyte system, and then to cholangiocyte system in the next week. Like oval cells in the adult liver, the hepatic stem cells mainly locate at the periportal region at 10-12 wk.

wk， 肝干细胞开始向肝细胞系分化， 7 wk向胆管系分化， 10-12 wk，肝干细胞主要局限于汇管区周围的肝索，与成年肝中卵圆细胞的分布一致。

Results: Human stem cells were successfully transplanted into 6 fetal sheep and 5 lambs were born and lived. PCR analysis showed that there was human derived cell engraftment in the liver of the 5 lambs. Immunohistochemical staining and ISH with Alu probe showed human derived hepatocytes in the lobes or around periportal area, expressing albumin and CR18. Alu ISH also showed there were positive cells in the epithelia of bile duets.

结果：在移植的 6 只胎羊中，5 只顺利生产；PCR 检测显示 5 只实验羊肝脏组织中均有人源性细胞的嵌合：免疫组化及 Alu 探针原位杂交显示人源性细胞分布於门管区周围和肝小叶中，表达白蛋白、CK18 等肝细胞分化标志；Alu 探针阳胜细胞也分布於胆管上皮中。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐