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胆碱酯酶

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Myasthenic symptom was not clianged in one patient for whom radiotherapy had been standed before operation nor during the course of postoperative radiotherapy.

单次剂量1.8~2.0Gy的照射方式不会加重肌无力症状,但放疗中必须应用合理的抗胆碱酯酶药物,密切观察肌无力变化,及时调整药物治疗方案。

Some are slowly progressive and a myopathic EMG may occur if there is an associated endplate myopathy (eg, in slow channel syndrome or acetylcholine esterase deficiency) or in DOK7 synaptopathy.

一部分缓慢进展,当伴随有终板的改变(如:在慢通道综合症或胆碱酯酶缺乏)或者在DOK7突触病时,EMG呈肌源性改变。

However, fully consideration of special structure and physiological function of CRP is critical to investigate whether CRP provide protect effect or pathogenic effect in the progression of atherosclerosis. CRP is a member of pentrxins family, which consists of five identical, noncovalently associated 23-kDa protomers arranged symmetrically around a central pore with a 102 A external diameter. Each protomer has a recognition face with a phosphocholine binding site consisting of two coordinated calcium ions adjacent to a hydrophobic pocket. The opposite face of the pentamer is the effector face, where complement Clq binds and Fc receptors are presumed to bind. A cleft extends from the center of the protomer to the central pore of the pentamer. Both faces ofpentamer form a special bi-phase structure: one face is the ligand recognition phase, which can recognize apoptosis cells and enzyme modified low density lipoprotein in which PCh is exposed.

CRP是一种五聚体蛋白,外径为102 A,由5个相同的单体以非共价键结合,形成双面的环形结构,每个单体的配体识别位点或受体结合位点分别位于五聚体两个平面上,分别组成配体识别相和效应器相,从而构成特殊的二相性结构:一面为配体识别相,含有磷酸胆碱(phosphorycholine,PCh)结合位点,能够使CRP识别在病理条件下暴露出PCh的凋亡细胞、酶修饰低密度脂蛋白(enzyme modified low density lipoprotein,E-LDL)等。E-LDL是天然低密度脂蛋白(native Low density lipoprotein,N-LDL)在多种蛋白酶,如胰蛋白酶、神经氨酸酶、胆固醇酯酶等作用下的代谢产物,其主要特点是结构发生改变(N-LDL大小均匀,平均直径250±30 A,E-LDL大小差异极大,直径为100-2000 A),暴露磷酸胆碱位点,能够被CRP识别;另一面为效应器相,能够与巨噬细胞、单核细胞表面受体FcγRⅡa结合,介导巨噬细胞、单核细胞识别及吞噬凋亡、坏死细胞作用。

Effects of the anticholinesterase agent may be antagonized.

胆碱酯酶剂的效果可能被对抗。

Here the screen-printed electrode is used as the base,and a novel amperometric biosensor's enzyme electrode is constructed by entrapping the gelatin film.

现以丝网印刷电极为载体,以明胶包埋为主要方法制备了基于乙酰胆碱酯酶和胆碱氧化酶的电流型生物传感器酶电极,并对其性能进行了一系列评价,发现该酶电极在pH值为6。

Abstract] Goal: The summary analysis monitor choline esterase activeness rescue organic phosphorus insecticide is poisoned is for extremely when adjusts Arab Leaguerequest the medicine use, enhances it curing rate.

目的:总结分析监测胆碱酯酶活性抢救有机磷杀虫药中毒是为极时调整阿托品的药物使用,提高其治愈率。

Results The average medication for treatment group is(5.1±2.5) times,ChE recovering average time is (18±1.4)h,average hospitalization time is (4.4±2.5)d,Atropin poison ...

结果治疗组平均用药(5.1±2.5)次,胆碱酯酶恢复时间平均为(18±1.4)h,平均住院时间为(4.4±2.5)天,阿托品中毒2例,死亡3例。

In this reseach we observed the clinical symptoms induced by soman intoxication in dogs at sea level and at a simulated high altitude of 4000 metres.

梭曼是强有力的不可逆胆碱酯酶抑制剂之一,本文以犬急性梭曼中毒为模型,分别在平原和模拟4000m高原观察梭曼中毒后临床特征的动态变化。

By using local intoxication of soman (pinacolyl methylphospho-nofluoridate) the processes of regeneration of AChE activity at motor end-plates and of recovery of neuro-muscular transmission of rat diaphragm were observed. An ameliorative effect of HI-6 on these processes was also observed.

用大鼠的在体膈肌局部索曼中毒法,观察了乙酞胆碱酯酶在运动终板的再生和肌接头传递功能的恢复过程,以及肪类药物(HI-6)对两过程的促进作用。

Self-learn the process of hydrolysis of acetylcholine by cholinesterase.

了解乙酰胆碱直接产生的M、N样作用、抗胆碱酯酶药间接产生M、N样作用方式。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。