胆碱酯酶

The effects, of protection and treatment with, combined Ch, NaF and a trophie were significantly better than that with atropine alone. In isolated phrenic nerve-diaphragm preparation of rat, isolated jejuneal preparation of, guinea pig, and the metabolic experiment of rat liver, the results of the, assay on the rat blood ChE activity indicated that antidotal effect of NaF may be due to the antidese...

大鼠离体膈神经膈肌、豚鼠离体空肠和大鼠肝脏代谢实验及对大鼠全血胆碱酯酶活力测定的结果表明，NaF的抗毒作用可能是由于其对神经肌肉接头和/或神经节中的N受体的抗脱敏作用；而Ch则可能通过其对ChE的保护和/或加速被抑制ChE的复能，阻碍Ach到达M受体部位而发挥作用。

The relationship of the change of ChE and prognosis was monitored dynamically in48hepatic cirrhosis incorporating with acute organophos-phorus poisoning patients selected and treated in hospital,then compared with antithetic group.

摘要］目的研究肝硬化肝功能Child-Pugh A级患者合并急性有机磷农药中毒时血清胆碱酯酶活力的变化以及对治疗预后的影响。

Objective To study the relationship of serum cholinesterase and total bile acid levels with liver injuries in patients with chronic hepatitis B.

目的探讨血清胆碱酯酶、总胆汁酸与慢性乙型肝炎肝脏病理损害的关系。

Two basic types of cholinesterase activity are found in the tissues of all animals.

所有动物的组织内部都有两种基型的胆碱酯酶活性。3。机能，功能

The molecular charge distribution of the reactivator is affect the reactivating efficacy directly. Moreover its association with hydroximic acid dissociation constant pAa closely, and it will have a great impact on reactivating ability indirectly.(3) There is likely to exist front molecular interaction between Cholinesterase Reactivators and OPC-inhibited AChE, the action sites mainly lie on the aromatic ring, the substitute R and the hydroixic acid group. They act on the aromatic residues of AChE by Π-Π conjugation .(4) The reached results by Comparative Molecular Field Analysis is useful to design new higher efficacy derivatives for 1, 2, 4-oxadiazole class nonquaternary Cholinesterase Reactivators.

2复能剂分子的电荷分布直接影响复活活性，同时对肟酸解离常数pKa具有重要影响，间接影响复活能力；(3)复能剂与磷酰化酶可能存在前线轨道作用，作用部位可能主要在芳香环及其取代基R和肟基上，与AchE的芳香族残基发生л-л电子作用；(4)通过比较分子力场法研究可以指导1，2，4-oxadiazole类非季铵肟胆碱酯酶重活化剂新化合物的合成，可能得到活性更高的复能剂。

Alb, Che and PA were examined by end-point method, enzyme kinetics and immunologic projective turbidimetry method respectively.

血浆清蛋白为终点法、胆碱酯酶为酶动力学法、及前白蛋白免疫投射比浊法。

Therefore, the aim of this research is to compare the antioxidant, acetylcholinesterase-inhibiting and monoamine oxidase -inhibiting activities of these four parts of Morus alba. In addition, I also explored the mechanism of the ameliorating effects of scopoletin on the scopolamine induced memory impairment in rats.

因此，本研究针对桑四个药用部位之甲醇抽提物进行抗氧化活性及对乙醯胆碱酯酶、单胺氧化酶的抑制活性之分析比较，之后再探讨其香豆素类成分 scopoletin对 scopolamine 诱发大鼠记忆障碍之影响，及其改善作用机制。

The mechanism of the ameliorating effects of scopoletin was related to the increase on the NE and DA concentrations in cortex by selectively inhibiting the activity of acetylcholinesterase and monoamine oxidase.

而桑之成分 scopoletin 具改善scopolamine 诱导大鼠记忆障碍作用，其机转与降低大鼠脑内皮质区乙醯胆碱酯酶及单胺氧化酶活性，增加皮质区内 NE 及 DA 浓度有关。

Finally, scopoletin ameliorated the scopolamine induced memory impairment on water maze and elevated plus maze in rats. Scopoletin selectively inhibited the activity of acetylcholinesterase and monoamine oxidase, and increased the NE and DA concentrations in cortex.

最后，scopoletin 於 0.03、0.1 mg/kg 剂量下，对 scopolamine 诱导大鼠在水迷宫以及十字迷宫学习操作障碍之现象均具有改善作用影响，此作用应与降低大鼠脑内皮质区乙醯胆碱酯酶及单胺氧化酶活性，增加皮质区内 NE 及 DA 浓度有关。

Effects of the experiment were evaluated by studies of (1) preoperative and postoperative gastric analyses,(2) retrograde tracing of horseradish proxidase to vagi, and (3) acetylcholinesterase activity of gastric tissue.

通过手术前后的胃液分析，术后（2周～4个月）辣根过氧化物酶对胃壁神经的逆行追踪及胆碱酯酶活性（AChE-activity）的测定来评价该设计手术的效果。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。