胆碱酯酶

Methods The levels of serum cholinesterase in 116 critical care patients and 30 normal people were detected with colorimetric method to find their difference.

对116例收入EICU 24h内的危重患者的血清胆碱酯酶水平进行测定，并测定30例正常人的血清胆碱酯酶水平对照分析，比较两组间的差异。

The level of serum cholinesterase can sensitively reflect the synthetic function and the damage of the liver.

肝硬化患者的血清胆碱酯酶活性测定有统计学意义，肝硬化患者与血清胆碱酯酶活性之间明显相关。

In this thesis, a series of derivatives of -Huperzine A and benzylpiperidine were designed and synthesized, including nonsteroidal anti-inflammatory drug derivatives, heterocycle derivatives, aromatic derivatives and its sckiff derivatives, etc.

全部目标化合物进行了胆碱酯酶的活性测试，石杉碱甲类衍生物的乙酰胆碱酯酶活性比母体差，说明该类取代基在胺基上取代可能会使石杉碱甲衍生物的活性降低。

And content of Ach was tested by alkaline hydroxylamine method.

用Morris水迷宫法测试小鼠的空间记忆能力，用比色法测定大脑皮质胆碱乙酰转移酶、胆碱酯酶活性，用碱性羟胺法测定乙酰胆碱含量。

Understand and familiarize with the classification of cholinergic agents, M effects, N effects, and also the pharmacological effects, clinical application and adverse reaction of physostigmine.

熟悉拟胆碱药的分类、M、N样作用、毒扁豆碱的作用、应用及主要不良反应；有机磷酸酯类中毒解救原则、胆碱酯酶复活药碘解磷定的作用机制和临床用途。

It has been demonstrated that TAK-147 is more potent and brain-specific AChE inhibition than tacrine and physostigmine, and has been approval potentiating choline acetyltransferase activity in cultured rat septal neurons more potent than donepezil, tacrine and revastigmine.

TAK－147 ｛ 3－［l一（phenylmethyl（－4－piperidinyl］－l一门，3，4，5－tetrahydro－IH－l－be.azepln－8－yi（－l－propanone umarate ｝是日本最近研制的一个选择性胆碱酯酶抑制剂。TAK－147与毒扁豆碱和他克林相比是具有更强作用和中枢选择性的胆碱酯酶抑制剂。

In the field of the agriculture, the organic phosphor and the amido formylesters were the insecticides which were broadly used for a long time.

根据胆碱酯酶对乙酰胆碱和丁酰胆碱的选择性水解作用可分为乙酰胆碱酯酶和丁酰胆碱酯酶。

Homology modeling of 3-D structure of two AChE from L.entomophila were constructed using H.sapiens(1p0i:A) native BuChE structure and Drosophila melanogaster(1d×4:A) native AChE structure as templates,respectively,by SWISS-MODEL.The catalytic triad were found and denoted in the 3-D structure of AChE from L. entomophila referring to T.californica.2.2 Gene cloning ofβ-actin and mRNA expression levels of two AChE genes from L. entomophilaBecause no reference gene has ever been used in Real Time PCR for L.entomophila in GeneBank,a fragment ofβ-actin gene was cloned from L.entomophila(GenBank Accession No.: FJ041117).It consists of 822 bp encoding a protein of 273 amino acids residues.

利用蛋白质结构同源建模工具，分别以人丁酰胆碱酯酶(1p0i：A)和果蝇乙酰胆碱酯酶(1d×4：A)的蛋白晶体结构为模板，对嗜虫书虱2个AChE的三维结构进行同源建模，并在三维结构中发现了AChE的酶解活性位点，证明嗜虫书虱体内也存在2个AChE基因。2.2嗜虫书虱β-actin基因克隆及乙酰胆碱酯酶基因mRNA表达水平研究目前关于嗜虫书虱的分子生物学研究较少，在GenBank中没有可用作内参基因的序列，因此本研究从嗜虫书虱体内克隆获得β—actin基因片段(GenBank登录号：FJ041117)，该片段长度为822 bp，编码273个氨基酸残基，同源性比对分析表明该片段与其它昆虫的β—actin基因具有很高的同源性。

Objective: To investigate the relationship among cholinesterase and Child -Pugh score of cirrhosis. To investigate the clinical significance of serum cholinesterase of patients with liver cirrhosis.

目的：探讨肝硬化患者Child-Pugh分级与血清胆碱酯酶(cholinesterase，ChE)活性的相互关系，以及肝硬化患者血清胆碱酯酶活性测定的临床意义。

Which can be used as the body of vitamin B1 coenzyme of many enzymes in the normal human body has an important role in glucose metabolism, it can inhibit the activity of cholinesterase, and choline esterase is an important neurotransmitter, and thus nerve conduction impact; vitamin B2 in the organization by participating in a variety of yellow enzymes constitute a coenzyme, its role in bio-oxidation process in the delivery of hydrogen role in regulating the body's metabolism process; vitamin B6 can also be a variety of enzymes as coenzyme participate in all kinds of amino acid metabolism, promote the absorption of amino acids and protein synthesis, cell growth is necessary for the material, which also promote fat metabolism, involved in neurotransmitter synthesis, hemoglobin synthesis and the impact on the normal reproductive functions such as human body an important metabolic process, Volkswagen Medicine Net: What liver protection effect of vitamin B family?

可作为维生素乙许多酶的辅酶，在正常人体组织中有一个用糖代谢的重要作用，能抑制胆碱酯酶活性，和胆碱脂酶是一个重要的神经递质，神经传导，从而影响；由黄色参与各种酶在组织中维生素B2构成辅酶，其作用在生物氧化氢的作用，调节人体的代谢过程中产程；维生素B6也可以是作为辅酶参与氨基酸代谢的各种酶的品种，促进氨基酸的吸收和蛋白质合成，细胞生长是必要的材料，这也促进脂肪代谢的神经递质合成，血红蛋白合成和参与，如影响人体生殖功能的正常新陈代谢过程中一个重要的，（大众医药网：什么样的维生素B家庭肝脏的保护作用？

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。