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To explore effects of nicotin cholinergic pathway on collagen induced arthritis in rats.

目的 探讨烟碱样胆碱能通路对胶原性关节炎的作用,为关节炎等自身免疫性疾病寻找新的治疗途径。

Objective To observe the effects of electric acupuncture on learning memory and cholinergic system for analyzing the mechanism of action of electric acupuncture for AD.

目的 通过观察电针对AD模型小鼠学习记忆水平和胆碱能系统相关指标的影响,阐明电针对AD的作用机理,为临床治疗提供实验依据和理论指导。

The mechanism may be related to reducing brain cholinesterase activity, inhibiting the accumulation of aluminium ions in brain, maintaining the normal level of Glu/GABA.Key words:Prepared Radix Rehmanniae; Learning and memorizing; Dysmnesia

结论熟地黄对于化学药品所致记忆障碍模型小鼠具有增强其学习记忆和空间记忆能力的作用,其作用机制可能与改善中枢胆碱能神经系统功能,降低脑内Al3 含量,保护脑组织及维持脑内Glu/GABA的正常水平有关。

In the present thesis study, the therapeutic effects of KXS on improving the ability of learning and memory of mice induced by scopolamine hydrobromide, ethanol or cerebral ischemia-reperfusion were investigated using both water maze and passive avoidance performance.

实验结果显示,KXS对以上多种模型动物均具有一定的改善作用,可以通过改善模型动物中枢胆碱能功能、提高中枢抗脂质过氧化能力、拮抗单胺类递质的异常变化等途径起效。

Dementia and cognitive impairments in Alzheimer's disease have been attributed to hypofunction of cholinergic system in the brain.

阿尔采默病导致的痴呆和认知障碍等症状,主要是由于脑内胆碱能突触传递受损引起的。

Nerve grows factor and brain-derived neurotropic factor, as one of the important active molecules, belong to neurotrophic family, which can affect the development of neuron and prevent neuron from damage.

神经生长因子(Nerve grows factor,NGF)和脑源性神经生长因子(Brain-derived neurotropic factor,BDNF)属于神经营养素家族,是神经系统重要的活性分子之一,是中枢神经系统胆碱能神经元、周围神经系统交感神经元及感觉神经元发育、分化、功能活动必不可少的营养分子。

Previous work has suggested that nicotinic inhibitioncould mediate the pronociceptive action of isoflurane.

以前的研究提示,胆碱能抑制剂可以调节异氟醚的早期痛觉作用。

Transported by axoplasmic flow into somata, NGF plays an important role in the development, preservation and survival of cholinergic neuron in BF.

药物损伤BF的胆碱能神经元,或切断穹窿海马伞使隔-海马的纤维投射破坏可导致海马θ节律消失和记忆能力减退。

In the previous observations we have found that neurokinins are involved in regulating excitotoxicity in the striatal and substantia nigra neurons.

进一步探讨神经激肽对基底前脑胆碱能神经元兴奋性毒性的调节作用,对于揭示AD的病理发生机制和探索其治疗策略,具有重要意义。

Acute organic phosphor is toxic clinical expression is systemic skeleton flesh and obstacle of gland form function, choline can high resemble and acute breathes exhaustion is his the main reason of inchoate death, machinery aerates cure is the key that saves patient life.

概要: 急性有机磷中毒临床表现为全身骨骼肌和腺体功能障碍,胆碱能危象并急性呼吸衰竭是其早期死亡的主要原因,机械通气治疗是拯救患者生命的关键。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。