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ChAc is an Ach's biological synthesizing enzyme and special mark of every cholinergic neuron.

ChAc是乙酰胆碱的生物合成酶,也是胆碱能神经元的特异标志酶,存在于所有胆碱能神经元,ChAc免疫反应活性被用于鉴别中枢和外周的胆碱能神经元。

Results:①In normal extracellular solution, the non-selective cholinergic agonist acetylcholine and the muscarinic agonist muscarine both caused the increace of [Ca2+]i in separately 21 out of 25 and 14 out of 18 VHCs I, while only 3 out of 20 and 2 out of 16 VHCs I had a weak increase of [Ca2+]i if investigated in calcium free extracellular solution; nicotine could increase the [Ca2+]i in 7 out of 32 VHCsⅠonly at enough high concentration(up to 10 mmol/L) in normal extracellular solution, this [Ca~(2+)]_i increase by nicotine at high concentration could not be investigated if at calcium free solution.

结果①非选择性胆碱能受体激动剂乙酰胆碱、M型胆碱能受体激动剂毒蕈碱在正常细胞外液中均可引起大部分(21/25, 14/18)单离VHCⅠ[Ca~(2+)]_i的升高,但无钙外液中ACh、muscarine仅使少部分(3/20,2/16)VHCⅠ[Ca~(2+)]_i升高且作用减弱;正常外液中,N型受体激动剂尼古丁仅在高浓度(≥10 mmol/L)时引起部分(7/32) VHCⅠ[Ca~(2+)]_i升高,在低浓度时对胞内钙离子浓度影响不明显,无钙外液中,10 mmol/L nicotine对胞内钙离子浓度影响不明显。

In conclusion, the current work has shown that NPY and AChE may originate from epithelial cells, the distribution of NPY, AChE have a close relation with behavior, regeneration and morphogenesis of Hydra pseudoligactis, NPY plays a role in development and differentiation of nematocyst, and ACh may function in emission of nematocyst.

水螅刺丝囊的分化和发育与NPY的作用密切相关;刺丝囊发射刺丝的机理与胆碱能的作用可能有联系[动物学报52(1):115-122,2006]。

Stimulation of cholinergic neurons promotes the release of the neurotransmitter dopamine in the reward pathway of your brain.

胆碱能的神经细胞的刺激能促进传感神经素多巴胺在大脑的有益通路中的释放。

Alphamethylscopolamine administered 30 min prior the pilocarpine has therefore been widely used to minimize peripheral cholinergic activation.

因此α-甲基东良菪碱在匹罗卡品之前30分钟注射,已经被广泛用于使外周胆碱能的活性最小化。

Ladder outflow obstruction secondary to BPH can decrease the densities of cholinergic nerve and receptor and damage the function of cholinergic nerve in bladder detrusor.

PH引起膀胱出口梗阻,梗阻可导致逼尿肌胆碱能神经和受体的密度降低,以及胆碱能神经功能减退。

The results mentioned above proved that the learning and memory disturbance induced by the damaged rat substantia innominata was central cholinergic system malfunction due to the cholinergic cell damage and asending fiber antergrade degeneration and cortex was lack of cholinergic contral.

本研究结果证明:鼠脑无名质区破坏引起的学习、记忆障碍,是由于中枢胆碱能细胞损害,引起胆碱能上行投射系统顺行性变性,致使大脑皮层失胆碱能支配,发生胆碱能系统功能低下所致。

In the adult, cholinergic neurons in the laterodorsal and pedunculopontine tegmental have been implicated in the generation and maintenance of REMS.

虽然在成年人和动物,胆碱能神经元被认为是主要的REM睡眠的调节神经元,已有实验证实脑桥网状结构及脚桥被盖核胆碱能神经元在REMS的触发和维持中起着关键作用,然而,胆碱能神经元对于幼年期REM睡眠的作用仍有待进一步的研究。

Some researchers have found that SP could affect other neurons in enteric nervous system . However, little is known about the mechanism of SP on the myenteric cholinergic neurons.

本研究采用全细胞膜片钳技术和免疫细胞化学技术探讨了SP对豚鼠回肠肌间丛胆碱能神经元电活动的影响,为揭示肽类递质对胆碱能神经元的调节机制提供依据。

It appears that glutamatergic and cholinergic inputs from the retina, and cholinergic and gabaergic inputs from NI may converge on tectal neurons in anurans.

因比,从视网膜来的谷氨酸能、胆碱能输入和从峡核来的胆碱能、GABA能输入共存于顶盖神经元。

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