胆碱

Objective To evaluate the efficacy and tolerability of tolterodine in patients with an overactive bladder.

目的 评价新型抗胆碱药物托特罗定治疗膀胱过度活动症的有效性和安全性。

Rat model of 35% total body surface area Ⅲ degree scald model were reproduced.

目的 研究烫伤休克大鼠肠内补液时给予卡巴胆碱对肠血管通透性及组织水肿的影响。

Trimethylamine and choline have similar structures to the substrate trimethylamine oxide and could be functioning as competitive inhibitors.

三甲胺和胆碱有相似的结构对基体三甲胺氧化物，能功能作为竞争抗化剂。

Choline chloride is one of B race vitamins and is synthesized by oxirane,hydrochloric acid and trimethylamine.

氯化胆碱由环氧乙烷、盐酸与三甲胺为原料合成，是B族维生素之一，是一种不能替代的饲料添加剂，市场上存在造假掺杂行为，对于各种掺杂行为进行分析识别，并提出鉴别方法

The patients with IMS,when they have difficulty in breathing,should be put under treatmentwith respirator and treated with pralidoxime in addition to aˉtropine.

IMS患者出现呼吸衰竭时应使用呼吸机治疗，同时合理使用阿托品、胆碱酯酶复能剂。

The results showed that (1) the positive staining of ChAT was obviously observed in the cells of the three kinds of human pituitary adenoma, however, it was lower than that in normal human pituitary gland;(2) ACh had a similar effect on the proliferation of the three kinds of human pituitary adenoma cells. ACh at 0.1～10 μmol/L decreased the ［3H］TdR incorporation and the MTT A value in a dose-dependent manner. At the same time, ACh decreased the ratio of S or G2 phase pituitary adenoma cells significantly, but increased the ratio of G1 phase pituitary tumour cells markedly;(3) the effect of acetylcholine on the proliferation of human pituitary adenoma cells was inhibited by atropine, but not by tubocurarine;(4) ACh had no effect on the apoptosis of human pituitary adenoma cells cultured in vitro.

结果发现：(1)三种垂体腺瘤细胞中均有胆碱酯酶的表达，但明显少于正常垂体；(2)ACh对三种类型的人垂体腺瘤细胞增殖代谢的影响相类似，不同浓度的ACh能明显抑制体外培养的三种人垂体腺瘤细胞的增殖，呈明显的剂量效应关系，同时ACh能减少垂体腺瘤细胞进入S、G2期的细胞比例，而使处于G1期的细胞比例增加；(3)ACh的这种作用可被阿托品阻断，但不受筒箭毒的影响；(4)ACh对体外培养的三种人垂体腺瘤细胞凋亡无明显影响。

Methods Serum transferrin of 100 patients with different types of hepatitis were determined with immuno turbidimetry and compared with prothrombin time, serum bilirubin and serum cholinesterase.

采用免疫比浊法检测100例不同临床类型病毒性肝炎病人的TF，同时检测凝血酶原时间、血清总胆红素、血清胆碱酯酶。

Alb, Che and PA were examined by end-point method, enzyme kinetics and immunologic projective turbidimetry method respectively.

血浆清蛋白为终点法、胆碱酯酶为酶动力学法、及前白蛋白免疫投射比浊法。

The organic acids increased totallateral pressure of DPPC monolayers, includingat mean molecular areas typical of bilayers.

这些有机酸增加单层二棕榈酸磷脂酰胆碱的总的侧向压力，包括双分子层的平均分子面积。

Methods:Chapter one The chapter is about the effect of galanthamine on the circulating TNF in rats with abdominal infection induced by endotoxin and effects of vagus nerve on galanthamine inhibiting inflammatory response.The models of rats with abdominal infection induced by endotoxin and the animal models of bilateral cervical vagotomy were produced.

目的：研究胆碱酯梅抑制剂加兰他敏对内毒素腹腔感染大鼠循环TNF的影响，迷走神经在加兰他敏炎症抑制效应中的作用；并研究加兰他敏对内毒素刺激后巨噬细胞活化的影响，阐述加兰他敏炎症调控作用的机理。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。