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胆碱

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By means of an improved separation method, we have prepared cytidine diphosphate choline from 5'-cytidine monophosphate and phosphoryl choline with Tsingtao beer yeast as enzyme source.

根据教学、科研、生产三结合的原则,以我国啤酒工业中常用的青岛啤酒酵母作酶制剂,用改进了的、适用于工业生产的提取方法制备了胞嘧啶核苷二磷酸胆碱,并用于小批量生产。

AIM: To investigate the antinociceptive effect of anticholinesterase agent physostigmine at different postoperative time, and the interaction of intravenous physostigmine with intrathecal morphine in rats.

目的:观察在术后不同阶段静脉注射胆碱酯酶抑制剂毒扁豆碱对鼠痛阈的影响,以及静注毒扁豆碱和蛛网膜下腔注射吗啡的药物相互作用。

The antinociception of physostigmine occurs at early postoperative time. The interaction of iv physostigmine with ith morphine indicates their synergistic effect.

胆碱酯酶抑制剂毒扁豆碱在术后早期产生镇痛作用;静注毒扁豆碱与蛛网膜下腔注射吗啡的联合给药呈协同效应。

The results indicated that an increase in BP, HR and the pressor response induced by the dPAG stmulation was caused by physostigmine microinjection without DKJ-21 pretreatment and no any change of BP and HR was observed after physostigmine administration with the pretreatment of DKJ-21. These results suggested that the location of central cholinergic system associated with the mechanism of the incidence of hypertension are mainly locate on the rVLM.

进一步的实验在正常血压大鼠上以DKJ-21预先处理后,由毒扁豆碱(0.4μg/0.1μl/site)微量注射至双侧rVLM引起的升压、加快心率、以及增强防御性升压反应的效应均被阻断,提示应激导致高血压时中枢内胆碱能系统活动异常增强的部位主要在于rVLM。

The next experiments were performed on the normotensive rat with or without pretreatment of DKJ-21, and then microinjection of physostigmine (0.4 ug/0.1 ul/site) into the rVLM bilaterally.

提示应激致高血压发病机制与中枢胆碱能系统活动的异常增强有关。

Alphamethylscopolamine administered 30 min prior the pilocarpine has therefore been widely used to minimize peripheral cholinergic activation.

因此α-甲基东良菪碱在匹罗卡品之前30分钟注射,已经被广泛用于使外周胆碱能的活性最小化。

Aim To observe the protective effects of choline and pilocarpine, the M3 receptor agonists, on the arrhythmias of Wistar rats induced by barium chloride.

目的 观察M3受体激动剂胆碱和毛果芸香碱对氯化钡诱发Wistar大鼠心律失常的保护作用。

To analysis bacterial-host infection, an in vitro experiment was first carried out to analyze the acid responses of Yersinia pseudotuberculosis, a gastro-intestinal bacterium, under acidic condition. Metabonomic variation of Y.

到21d时,天冬酰胺和组氨酸浓度降低,而缬氨酸、乳酸、丙氨酸、苹果酸、琥珀酸、GABA、胆碱、β-葡萄糖、果糖、尿囊素、苯丙氨酸、甲酸的含量增高。

Presented in this article is a report of synchronous determination of acetylcholinesterase and butyrylcholinesterase in finger blood established on the basis of the regression equation (Y = 0.149 8X+22.483 5) where hemoglobin is highly correlated with hematocrit (r = 0.999 2, P.001), with quinidine sulphate as the specific inhibitor of BChE.

本文根据全血的血红蛋白含量与红细胞压积容量的高度相关性的回归方程式(Y=0.149 8X+22.4835),以及用硫酸奎尼丁作为丁酰胆碱酯酶的特异性抑制剂,建立了指血乙酰胆碱酯酶和BChE活性的同步测定法。

The experiment concentratedly study the influence of Bushen Huoxue Huatan Prescription from multilateral and multilager in treating the dementia rats whose cholinergic nerve cells are injured.The study has suggested that the deficiency of essence Qi of kidney and insufficiency of brain marrow and the blood stasis and phlegm located in brain is the fundmental pathogenesis of begin prostatic hyperplasia, thus we bring forward the referentially experimental basis for the prevention and treatment of Alzheimers disease.

实验从多侧面、多层次集中研究了补肾活血化痰方对胆碱能损伤痴呆大鼠产生的影响,首次揭示了老年性痴呆"肾虚髓减,瘀血痰浊阻脑"病机理论的科学内涵,从而为老年性痴呆的预防和治疗提供了可供借鉴的实验依据。

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