胆碱

Objective To evaluate the efficacy and safety of the injectable phosphatidycholine used for fat-dissolving.

目的：观察磷脂酰胆碱注射溶脂的有效性和安全性。

Atropine is a specific antidote for the cardiovascular collapse that may result from the injudicious administration of a choline ester.

阿托品是治疗由于用胆碱酯类不慎而引起的心血管性虚脱的特效解毒剂。

Secretion of sweat occurs as result of many factors and is mediated by cholinergic innervation.

汗液的分泌受胆碱能神经支配，是多种因素作用的结果。

Recent evidence indicates that the cholinergic innervation of the left ventricle is functionally very important in some mammalian species.

近年来的研究显示在一些哺乳动物的心脏上，胆碱能神经在心室也有分布，且对左心室的功能有重要的调控作用。

Objective To observe the effect of nerve growth factor on cardiac cholinergic innervation in rat with myocardial infarction to oxplore the effect of NGF in treatment of AMI.

目的 观察神经生长因子对大鼠心肌梗塞后胆碱能神经的影响，探讨NGF对心肌梗塞的可能治疗作用。

L Acute angle-closure glaucoma is an ocular emergency that requires immediate management, including topical cholinergic and hyperosmotic agents with laser peripheral iridotomy or surgery iridectomy.

急性闭角青光眼属于眼科急诊，需要立即进行治疗，包括胆碱能和局部用药，配合激光周边虹膜切开术或手术虹膜切除术。

The molecular charge distribution of the reactivator is affect the reactivating efficacy directly. Moreover its association with hydroximic acid dissociation constant pAa closely, and it will have a great impact on reactivating ability indirectly.(3) There is likely to exist front molecular interaction between Cholinesterase Reactivators and OPC-inhibited AChE, the action sites mainly lie on the aromatic ring, the substitute R and the hydroixic acid group. They act on the aromatic residues of AChE by Π-Π conjugation .(4) The reached results by Comparative Molecular Field Analysis is useful to design new higher efficacy derivatives for 1, 2, 4-oxadiazole class nonquaternary Cholinesterase Reactivators.

2复能剂分子的电荷分布直接影响复活活性，同时对肟酸解离常数pKa具有重要影响，间接影响复活能力；(3)复能剂与磷酰化酶可能存在前线轨道作用，作用部位可能主要在芳香环及其取代基R和肟基上，与AchE的芳香族残基发生л-л电子作用；(4)通过比较分子力场法研究可以指导1，2，4-oxadiazole类非季铵肟胆碱酯酶重活化剂新化合物的合成，可能得到活性更高的复能剂。

Undergoing elective surgery were randomly divided intothree groups acˉcording to the method of the induction of general anesthesia,i.e GroupⅠ（n=13）:intravenous induction:midazolam0.03mg/kg,fentanyl3μg/kg ,etomidate0.3mg/kg,vecuronium1mg and succinylcholine1.5mg/kg;GroupⅡ（n=13）:orolaryngeal lignocaine spray combined with intravenous induction,lignocaine administered just before the inducˉtion of anesthesia;GroupⅢ（n=13）:epidural block combined with general anesthesia,2%lignocaine3ml adminˉistered via epidural catheter before the induction.

组Ⅰ为单纯经静脉全麻诱导组，麻醉用药为咪唑安定0.03mg/kg、芬太尼3μg/kg 、依托咪酯0.3mg/kg、维库溴铵1mg和琥珀胆碱1.5mg/kg；组Ⅱ为诱导即刻咽喉部喷雾表麻加经静脉全麻诱导组；组Ⅲ为硬膜外阻滞加经静脉全麻诱导组。

It was found that theintrduction of polar phosphatidylcholine to LLA chains had largely changed thehydrophilicity of the synthesized polymers. And from the research ofendothelioid cell (ECV304) compatibility and adhesion of blood platelet, wefound that the cells adhesion of ECV304 on the films of PLLA-PC-PLLA lagedcomparing to PLLA, but then could proliferate and cover the films in total,PLLA-PC-PLLA, the same as PLLA are not cytotoxicity and ECV304 canattach and proliferate on them, and PLLA-PC-PLLA can reduce the adhesion ofblood platelet.

结果表明：由于聚乳酸中磷脂酰胆碱结构的引入，使得该材料的亲水性得到很大的改善，并且随着聚合物中磷脂结构单元比例的增高其亲水性能就越好；通过对该材料进行细胞亲和性的实验研究，发现这种材料能够使细胞锚着并支持细胞的增殖；而血小板黏附的实验结果初步显示了该材料具有较好的抗血小板黏附的性质。

Distinct interaction was found between scopolamine and morphine on increasing locomotor activity.

暗示吗啡和胆碱能拮抗剂对小鼠空间记忆提取的破坏存在一定程度的相互作用。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。