胆的

Bicyclic compounds containing a phenyl or pyridyl ring fused to a cycloalkyl or heterocyclic ring, to which is attached a 5-membered heterocyclic ring, including pharmaceutically acceptable salts and prodrugs thereof, are agonists of G-protein coupled receptor 40 (GPR40) and are useful as therapeutic compounds, particularly in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.

本发明涉及含有连接在5元杂环上的稠合至环烷基或者杂环的苯基或者吡啶基环的二环化合物，包括其药学上可接受的盐和前药，它们是G蛋白偶联受体40(GPR40)激动剂并且可以用作治疗性化合物，特别是在2型糖尿病和与这些疾病相关的症状中用作治疗性化合物，这些症状包括肥胖病和脂质疾病，比如混合或者糖尿病型血脂异常症、血脂质过多、高胆甾醇血和高甘油三酯血症。

Hitler was not only an avid reader but also an inveterate underliner. Perhaps the most chilling example of that is in Paul de Lagarde's "German Essays". Underlined is:"Each and every irksome Jew is a serious affront to the authenticity and veracity of our German identity."

作者告诉我们希特勒不仅读书热心，而且还有在书上划线的习惯，其中就有一处看得令人胆寒，那是在Paul de Lagarde所著的《德国随笔》中的一句，&可恨的犹太佬严重侮辱了我日耳曼忠厚老实的民族性格。&

Approximately some 1/4 unio primary bile acid in the jejunum,the ileum and the colon upside ,with the effect of enzyme's catalysis,produces the deoxycholic acid,the lithocholic acid ,the bear deoxycholic acid and etc.

大约有1/4的结合型初级胆汁酸在空肠、回肠及结肠上段，在细菌的酶的催化下，进一步生成去氧胆酸、石胆酸、熊去氧胆酸等次级胆汁酸。C·胆汁酸的合成：肝细胞合成的胆汁酸与甘氨酸或牛磺酸结合，形成结合型胆汁酸，分泌入胆道。

Paul "Wiggy" Wade-Williams, author of the Pirates of the Spanish Main RPG, dropped me an email saying some very flattering and complimentary things about Brimstone and Gall .

郑明训& wiggy &韦德-威廉姆斯，作者之一的海盗，西班牙的主要 RPG游戏，下降我一封电子邮件，说一些很阿谀奉承的和互补的东西，约硫磺和胆。

My Adidas.. My Adidas standin on 2 Fifth St. funky fresh and yes cold on my feet with no shoe string in em, I did not win em I bought em off the Ave with the black lee denim I like to sport em that's why I bought em a sucker tried to steal em so I caught em and I thwart em and I walk down the street and I bop to the beat with Lee on my legs and adidas on my feet and now I just standin here shooting the gip me and D and my Adidas standing on 2 Fifth My Adidas.. My Adidas..

我爱迪达。。我爱迪达standin二日第五届圣胆源性新鲜寒冷我是无脚的鞋在弦电磁、我不买我赢电磁电磁序幕动态与李黑牛仔我喜欢体育电磁就是为什么我买了电磁电磁吸盘试图窃取我和我陷入电磁电磁挫败我走上街头巡逻，以收支平衡和我同我的腿利安我爱迪达而现在，我的脚刚standin这里拍摄的岛屿总产值和D我和我爱迪达站在了FIF2 次我爱迪达。。

But his display of talent and moxie against the Lakers in the Finals put to bed talks of his demise and reinserted his name into the minds of basketball fans.

但是当雷阿伦出现在总决赛的赛场对阵湖人的时候，他却是展示出了自己最大的能耐和胆色，对於球迷的一些很负面言论如&阿伦不行了，该是时候退下让位了&，他的出色表现都把那些言论都击得粉碎。

The slogan is still popular, but it has been chillingly reinterpreted. Now it refers to the growing phenomenon of suicide bombing, one of the most toxic developments of the current intifada.

这个口号仍很流行，但多了令人胆寒的新意，它如今指的是日渐增多的自杀爆炸现象，是当下&起义&的一个最为恶劣的动向。

For four months now, Hayden Christensen has been working out like a fiend and basically scarfing down everything he can lay his hands on in order to bulk up for his role in the next Star Wars where his Anakin Skywalker will finally evolve into the dreaded Darth Vader.

现在为止的四个月时间里，海登·克里斯腾森进行了魔鬼式的训练，为了扮演下一部《星战》中那个最终将转变为令人胆寒的达斯·维达的阿纳金，他必须让自己强壮起来，为此，他基本上把自己能弄到的一切办法都用上了。

Also, you would not need to try and redistribute the filling of the Air Pillow as you would with a normal pillow which are mainly filled with thick sponge, scraps of foam, cloth scraps or other fibrous material.

使用气枕后，当你疲劳或头痛时，由于气胆内装入了空气，你无需移动头部，找到让你舒服的睡姿，也无需重新调整枕头内的填充物，如海绵、棉肖、布碎等其他纤维物料，气枕能舒服地承托你的头部及头部外的部分体重。

The PVA without limiting the blood flow volume can increase the cross section and blood flow volume of portal vein ,dilate and thicken the branches of portal vein, but the function of reticuloendothelial system, metabolism of bile pigment and bile acid salt don′t undergo significant influences.

未采取限流措施的门静脉动脉化可导致门静脉横截面积和血流量增加，门静脉分支扩张、管壁增厚，但网状内皮系统的吞噬功能以及胆色素和胆盐的代谢未受显著的影响。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。