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胆汁酸

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To detect the marks reflecting the liver functions as follows:①The marks to reflect the capability to synthesize proteins, TPROT, ALB, GLB;②The marks to reflect the injury of the liver cells: AST, ALT, CHE;③The marks to reflect the capability to egest the bile, excrect, and detoxicate: TBILI, DBILI, IBILI, TBA;④The enzymes to reflect the cholestasis: GGT, ALP. Results The results of both the morphological and the pathological studies showed that the degree of the liver cirrhosis was of the terminal stage.

肝功能指标:①反映肝细胞蛋白合成代谢功能的指标:总蛋白TPROT,白蛋白ALB,球蛋白GLB;②肝细胞受损的指标;谷草转氨酶AST,谷丙转氨酶ALT,胆碱脂酶CHE;③反映肝脏胆排泄、分泌及解毒功能的指标:总胆红素TBILI,直接胆红素DBILI,间接胆红素IBILI,总胆汁酸TBA;④胆汁淤积指示酶:谷氨酰转肽酶GGT,碱性磷酸酶ALP。

Results: Elevated levels of unconjugated bilirubin(P.01)and Ga2+(P.05),decreased levels of total bile acid(P.01)and cholesterol(P.01)were found.

结果:乙肝病毒感染患者胆囊胆汁的非结合性胆红素、钙离子明显高于对照组(P.01,P.05),总胆汁酸、胆固醇明显低于对照组(P.01)。

Lithogenous diet caused liver damage, then abnormality of metabolism of bile acids, and promoted gallstone formation.

致石食物首先引起肝脏病理损害,继而导致胆汁代谢紊乱,尤其是胆汁酸代谢紊乱,促使了胆结石的形成。

The bile acid,phosphoˉlipid and cholesterol in the bile of gallbladder were analyzed by chromatograph of liquid and the gallbladder was examined by both light and electron icroscope.Results At the end of the6 th week,none of the group N had gallstone.

饲养6周后处死观察胆囊结石形成情况,测定胆囊胆汁中胆汁酸、磷酸、胆固醇,观察胆囊超微结构的变化以及糖尿病模型的胰腺病理改。

Killed at the end of the6 th weeks of fedding,the condition of stone formation in the gallbladder was observed.The bile acid,phosphoˉlipid and cholesterol in the bile of gallbladder were analyzed by chromatograph of liquid and the gallbladder was examined by both light and electron icroscope.

饲养6周后处死观察胆囊结石形成情况,测定胆囊胆汁中胆汁酸、磷酸、胆固醇,观察胆囊超微结构的变化以及糖尿病模型的胰腺病理改。

Taurocholic Acid is a kind of tauro-conjugated bile acid which exists in many kinds of animals' bile.

牛磺胆酸(Taurocholate acid, TCA)是存在于多种动物胆汁中的一种结合型胆汁酸

Serum alt, ast, bile acid and albumin levels were measured with automatic biochemistry analysator during the procedure.

采用ccl4造模,全自动生化分析仪检测血清丙氨酸氨基转移酶、天门冬氨酸氨基转移酶、胆汁酸及白蛋白水平;he染色和vg染色观察肝脏病理及纤维化面积的变化,分析黄芪对肝功能及肝纤维化形成的影响。

The protective effect against hepatic damage was evaluated by measuring alanine aminotransferase, aspartate transaminase, total bilirubin, total bile acid, albumin, prothrombin time and child-pugh score at admission and after treatment.

同时监测治疗前后肝功能指标血丙氨酸转氨酶、天冬氨酸转氨酶、总胆红素、总胆汁酸、白蛋白、凝血酶原时间及child-push评分并进行对照比较。

Result: Peppermint oil 120、60、30 mg/kg giving into duodenum could significantly increase the secretion volume of bile in rat, and slightly increase the concentration of cholic acid in bile. Peppermint oil 5, 0.5 and 0.05mg/L has no dissolving effect on cholesterol gallstone and bile pigment gallstone in 4~5 weeks.

结果:薄荷油120、60、30mg/kg十二指肠给药,对大鼠有明显的利胆作用,并能轻度增加胆汁中胆汁酸的排出量。5、0.5、0.05mg/L在4~5周内对胆固醇结石、胆色素结石无明显溶解作用。

Both diabectic angiopathy and lipid soakage are presented in group DMCH.Conclusion It was confirmed that there was rather high rate of cholecysts stone forming in the rabbits with DM led by Alloxan,that the bile acid,phospholipid reduced and cholesterol increased in the

证实四氧嘧啶致糖尿病大耳白兔胆囊结石形成率甚高,胆囊胆汁酸分泌减少、磷脂减少和胆固醇增加形成成石胆汁,以及形成胆囊微血管病变是胆石形成的重要因素,为深入研究提供了有用的工具。

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