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胆汁盐

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In some cases a stone can be treated by giving the patient bile salt s, which help redissolve cholesterol.

某些病例可行内科治疗,如口服胆盐以溶解结石及降低胆汁中的胆固醇浓度。

"Bile contains bile acids and salt s, cholesterol, and electrolyte chemicals that keep it slightly acidic."

胆汁中包含胆汁酸和胆汁盐、胆固醇及电解质等,保持胆汁呈微酸性。

Bile tolerance, deconjugation of conjugated bile salt, and cholesterol-assimilating ability of 8 strains from Lactobacillus plantarum were examined.

对8株植物乳杆菌的胆汁耐受力、降解结合胆盐能力以及同化胆固醇能力进行了研究。

Progressive familial intrahepatic cholestasis is caused by mutations of the bile salt export pump or the multidrug resistance P-glycoprotein, resulting in chronic hepatic failure.

进行性家族性肝内胆汁淤积症是因为胆盐输出泵或多药耐药性P-糖蛋白突变的结果,常常导致慢性肝功能衰竭。

ABCB11 gene encodes bile salt export pump. It is almost exclusively expressed in the canalicular microvilli of liver. It is the principal conveyor of bile acids from hepatocyte cytoplasm into bile canaliculus.

人类ABCB11基因编码产生胆盐输出泵,BSEP是位于肝细胞毛细胆管面上的重要转运体,将胆盐从肝细胞内转运到毛细胆管中,是形成胆汁流的最主要动力。

This osmosensation of luminal tonicity by ciliary TRPV4 involves apical ATP release and purinergic receptors and induces apical bicarbonate secretion, the main determinant of ductal bile formation.

这种通过纤毛TRPV4引起腔内张力的渗透包含顶端ATP的释放,嘌呤受体,引起顶端碳酸氢盐的分泌,而碳酸氢盐正是管道胆汁形成的主要决定物质。

Although the couplets number and morphology are similar in both genotypes, fluorescence assay showed significantly decreased bile secretion into canalicular space of hepatocyte couplets in AQP8 null mice compare with wild type mice.

为了避免胆管对胆汁形成修饰作用,我们使用胆盐刺激小鼠,加快胆汁分泌的速度,结果仍显示,AQP8基因敲除小鼠的胆汁分泌量明显少于野生型小鼠。

The mean conˉcentrationsof the total bile acid in the gallbladders were respectively77.53±11.93,51.81±8.12and53.27±7.04in group DM,CH and DMCH,but it was79.28±18.28in group N.Combined bile acids(both glycocholic acid and taurocholic acid)were apparently lessened and the ratio of cholic acid and chenodeoxycholic acid was rised in group DM,CH and DMCH,the concentrationsof cholesterol were respectively5.31±0.81,5.69±2.20and5.12±1.47,but0.86±0.20,in the group N;those of phospholipd were respectively0.35±0.16,0.52±0.18and1.38±0.34,but0.59±0.28,group N.

胆囊胆汁成分分析中,DM组、CH组和DMCH组总胆汁酸分别为77.53±11.93、51.81±8.12和53.27±7.04,N组为79.28±18.28;与N组比较结合胆汁酸减少,其中甘氨胆汁酸盐与牛磺胆汁酸盐均减少;鹅去氧胆酸减少,胆酸/鹅去氧胆酸比值升高;胆汁胆固醇分别为5.31±0.81、5.69.20和5.12±1.47,N组为0.86±0.20;磷脂分别为0.35±0.16、0.52±0.18和1.38±0.34。

Stones were seen in the gallbladder of12/12cases in either group DM and CH,and11/12in the group DMCH.The mean conˉcentrationsof the total bile acid in the gallbladders were respectively77.53±11.93,51.81±8.12and53.27±7.04in group DM,CH and DMCH,but it was79.28±18.28in group N.Combined bile acids(both glycocholic acid and taurocholic acid)were apparently lessened and the ratio of cholic acid and chenodeoxycholic acid was rised in group DM,CH and DMCH,the concentrationsof cholesterol were respectively5.31±0.81,5.69±2.20and5.12±1.47,but0.86±0.20,in the group N;those of phospholipd were respectively0.35±0.16,0.52±0.18and1.38±0.34,but0.59±0.28,group N.

胆囊胆汁成分分析中,DM组、CH组和DMCH组总胆汁酸分别为77.53±11.93、51.81±8.12和53.27±7.04,N组为79.28±18.28;与N组比较结合胆汁酸减少,其中甘氨胆汁酸盐与牛磺胆汁酸盐均减少;鹅去氧胆酸减少,胆酸/鹅去氧胆酸比值升高;胆汁胆固醇分别为5.31±0.81、5.69.20和5.12±1.47,N组为0.86±0.20;磷脂分别为0.35±0.16、0.52±0.18和1.38±0.34。

In cholestatic rats, increased MCP-1 positively correlated with taurocholate in serum and liver, and negatively correlated in bile.

在胆汁郁积的大鼠,所增加的MCP-1与血清和肝中牛磺胆酸盐的呈正相关,并与胆汁呈负相关。

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