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胆汁分泌

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MethodsThe antipyretic activity of ***PS was observed in rats with high temperature induced by dried yeast and 2,4-dinitrophenol; biliary duct cannula bile at 0.5,1,1.5,2,2.5 h after intraduodenal administration in rats was collected and counted to observe the effect of ***PS on biliary secretion;the weight of cholecyst in mice was counted to observe the effect of ***PS on the cholecyst of mice;the acute toxicity test of ***PS was done with mice.

方法采用干酵母、2,4二硝基苯酚致大鼠发热的模型观察玉米须多糖的解热作用;采用胆管引流法分别收集并计量给药后0.5,1,1.5,2 ,2.5 h的胆汁的方法观察***PS对肝脏分泌胆汁的影响;采用测定小鼠胆囊重量的方法观察***PS对胆囊的影响;对***PS进行了小鼠急性毒性实验。

To detect the marks reflecting the liver functions as follows:①The marks to reflect the capability to synthesize proteins, TPROT, ALB, GLB;②The marks to reflect the injury of the liver cells: AST, ALT, CHE;③The marks to reflect the capability to egest the bile, excrect, and detoxicate: TBILI, DBILI, IBILI, TBA;④The enzymes to reflect the cholestasis: GGT, ALP. Results The results of both the morphological and the pathological studies showed that the degree of the liver cirrhosis was of the terminal stage.

肝功能指标:①反映肝细胞蛋白合成代谢功能的指标:总蛋白TPROT,白蛋白ALB,球蛋白GLB;②肝细胞受损的指标;谷草转氨酶AST,谷丙转氨酶ALT,胆碱脂酶CHE;③反映肝脏胆排泄、分泌及解毒功能的指标:总胆红素TBILI,直接胆红素DBILI,间接胆红素IBILI,总胆汁酸TBA;④胆汁淤积指示酶:谷氨酰转肽酶GGT,碱性磷酸酶ALP。

After finish the digestion, then flow back to the blood.also, during the period of liver and gallbladder concertrate in the hepatoenteral circulation,the bile acid can drain massively with the excrement.and more seriously after adding the fat feed stuff.if this condition go on, the fat cannot be absorbed in time and the energy will be wasted and cause some disease and etc.but after adding the appropriate exogenetic emulsifier,the question can be solved.

作为正常的机体,胆汁酸由肝脏分泌,进入肠道,在完成消化,回流入血液,又在肝脏和胆囊重新富集的肝肠循环的过程中,会经过粪便大量流失。在脂肪含量较高的饲料配方下,流失更为严重。日肝脏分泌量不足弥补流失量,会造成脂肪消化的阻滞,能量的浪费,且易诱发肝胆代谢紊乱等各种疾病。得不到消化吸收的油脂,在肠道内被噬油微生物降解,使噬油微生物类群大量增殖,打破原来肠道内微生态平衡,产生腹泻等菌群失调症,以上的问题,都是由于脂肪乳化作用不足和脂肪代谢失调造成的。在补充了合适本物种须求的外源性乳化剂后,问题可得到解决。

Methods The antipyretic activity of SMPS was observed in rats with high temperature induced by dried yeast and 2,4-dinitrophenol; biliary duct cannula bile at 0.5,1,1.5,2,2.5 h after intraduodenal administration in rats was collected and counted to observe the effect of SMPS on biliary secretion;the weight of cholecyst in mice was counted to observe the effect of SMPS on the cholecyst of mice;the acute toxicity test of SMPS was done with mice.

采用干酵母、2,4二硝基苯酚致大鼠发热的模型观察玉米须多糖的解热作用;采用胆管引流法分别收集并计量给药后0.5,1,1.5,2 ,2.5 h的胆汁的方法观察SMPS对肝脏分泌胆汁的影响;采用测定小鼠胆囊重量的方法观察SMPS对胆囊的影响;对SMPS进行了小鼠急性毒性实验。

MethodsThe antipyretic activity of SMPS was observed in rats with high temperature induced by dried yeast and 2,4-dinitrophenol; biliary duct cannula bile at 0.5,1,1.5,2,2.5 h after intraduodenal administration in rats was collected and counted to observe the effect of SMPS on biliary secretion;the weight of cholecyst in mice was counted to observe the effect of SMPS on the cholecyst of mice;the acute toxicity test of SMPS was done with mice.

目的研究玉米须多糖的清热利胆作用及急性毒性。方法采用干酵母、2,4二硝基苯酚致大鼠发热的模型观察玉米须多糖的解热作用;采用胆管引流法分别收集并计量给药后0.5,1,1.5,2 ,2.5 h的胆汁的方法观察SMPS对肝脏分泌胆汁的影响;采用测定小鼠胆囊重量的方法观察SMPS对胆囊的影响;对SMPS进行了小鼠急性毒性实验。

MethodsThe antipyretic activity of SMPS was observed in rats with high temperature induced by dried yeast and 2,4-dinitrophenol; biliary duct cannula bile at 0.5,1,1.5,2,2.5 h after intraduodenal administration in rats was collected and counted to observe the effect of SMPS on biliary secretion;the weight of cholecyst in mice was counted to observe the effect of SMPS on the cholecyst of mice;the acute toxicity test of SMPS was done with mice.

方法采用干酵母、2,4二硝基苯酚致大鼠发热的模型观察玉米须多糖的解热作用;采用胆管引流法分别收集并计量给药后0.5,1,1.5,2 ,2.5 h的胆汁的方法观察SMPS对肝脏分泌胆汁的影响;采用测定小鼠胆囊重量的方法观察SMPS对胆囊的影响;对SMPS进行了小鼠急性毒性实验。

Both diabectic angiopathy and lipid soakage are presented in group DMCH.Conclusion It was confirmed that there was rather high rate of cholecysts stone forming in the rabbits with DM led by Alloxan,that the bile acid,phospholipid reduced and cholesterol increased in the

证实四氧嘧啶致糖尿病大耳白兔胆囊结石形成率甚高,胆囊胆汁酸分泌减少、磷脂减少和胆固醇增加形成成石胆汁,以及形成胆囊微血管病变是胆石形成的重要因素,为深入研究提供了有用的工具。

One of the four humors of the body thought in the Middle Ages to cause anger and bad temper when present in excess; yellow bile.

胆汁四种体液之一,在中世纪时被认为当分泌过多时会导致愤怒和暴躁脾气;黄胆汁

Archaic One of the four humors of the body thought in the Middle Ages to cause anger and bad temper when present in excess; yellow bile.

胆汁,黄胆汁,人的四种基本体液之一,中世纪时被认为当它分泌过多时,会导致人的愤怒和脾气暴躁。

Now it is considered that the formation of cholesterol gallstone must include follow conditions: decompensation of liver, secreting supersaturation hepatobile, broken balance of nucleating proteins with anti-nucleating proteins, and declining of gallbladder motility, which for bile to have enough time to form concretions in the gallbladder.

目前认为胆囊胆固醇结石形成必须具备以下条件:肝脏代谢紊乱,分泌过饱和肝胆汁,促成核因子和抑成核因子之间平衡的破坏及胆囊动力紊乱,使胆汁有充分时间在胆囊内形成结石。

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