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胆汁

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We have studied the electrochemical oxidation reactions of bilirubin, biliverdin, bile-purpurin and choletelin in H〓O+DMF mixed solvent and found that the oxidation reactions of these bile pigments were greatly sped up by the introduction of water into DMF, and discussed the effect of water on their oxidation mechanisms too, and determined the reaction rate constants in the mixed solvent.

利用现场紫外-可见及时间分辨光谱电化学技术,研究了胆红素、胆绿素、胆汁红紫素及胆黄素在DMF+H〓O混合溶剂中的电化学氧化反应,发现由于水的引入,使上述胆汁色素在DMF中的氧化反应大大加快。研究了反应的动力学,首次求出了反应的速率常数。

People's bile acid are cholic acid and the goose desoxy cholic acid.

如人的胆汁酸是以胆酸、鹅脱氧胆酸为主,而奶牛胆汁酸的主要成分为胆酸和脱氧胆酸,鸡体内脱氧胆酸含量很少,鹅脱氧胆酸的含量最高。

The free bile acid and dihydroxy bile acid glycine union(exisistence by the of non-ionic form ) also be absorb again through the simple proliferation way.this may occurs in any part of the small intestine and colon.

未结合的胆汁酸和二羟基胆汁酸的甘氨酸结合物,也过简单扩散的方式被重吸收。这种通过小肠膜的非离子化扩散可在小肠的任何部位及结肠发生。

Stduied on the recycling and reusing technology of the raw material and reagent at the extracting process.(3) Stduied on the pharmacokinetics of glycocholic acid in rat.

本文在实验室提取纯化牛羊混合胆汁中有效成分工艺的基础上,通过改进和完善工艺、扩大试验规模,建立了一套稳定、可靠的从牛羊混合胆汁中提取分离天然牛磺酸、胆酸、甘氨胆酸及牛磺胆酸的小试工艺技术路线,并对提取过程中废弃的的原料及试剂进行了回收套用研究,同时开展了有效成分甘氨胆酸在大鼠体内的药代动力学研究。

Depending on the above research, it can be said that it has been provided experimental basic for the further research in the middling experiment of extracting the active component from the mixed bovine and ovine bile, supplied the reliable theory and possibility for comprehensive delevoping utilizing the bovine and ovine bile, and illustrated the distribution variation law of glycocholic acid in the blood-serum and texture of rat which is regarded to helping developing the biocherical drug from animal organs.

旨在为下一步开展从牛羊混合胆汁中提取有效成分的中试实验研究奠定试验基础,为牛羊胆汁的综合开发利用提供可靠的理论依据和可能性,同时为阐明甘氨胆酸在大鼠血清及组织中的分布和变化规律,开发脏器生化药物新资源提供线索。

As the results showed that the significant relation between TCBA and calcium or magnesium, mainly between glycocholic, glycochenocholic or taurocholic acids and calcium or magnesium, could be found in all three groups but there was not any obvious relation between TCBA and ferrum or zinc except between glycocholic acid and zinc in gallbladder stone group.

由此可见前列腺素在胆结石形成中占有重要地位。花生四烯酸是合成前列腺素的前体,它在环氧化酶作用下形成前列腺素。本研究证实在成石性胆囊胆汁中花生四烯酸的含量(0.09%)和阳性率(71.74%)明显高于对照组(0.02%,21.42%),P.05。说明成石性胆汁为合成前列腺素提供了前体物质。

Methods The antipyretic activity of SMPS was observed in rats with high temperature induced by dried yeast and 2,4-dinitrophenol; biliary duct cannula bile at 0.5,1,1.5,2,2.5 h after intraduodenal administration in rats was collected and counted to observe the effect of SMPS on biliary secretion;the weight of cholecyst in mice was counted to observe the effect of SMPS on the cholecyst of mice;the acute toxicity test of SMPS was done with mice.

采用干酵母、2,4二硝基苯酚致大鼠发热的模型观察玉米须多糖的解热作用;采用胆管引流法分别收集并计量给药后0.5,1,1.5,2 ,2.5 h的胆汁的方法观察SMPS对肝脏分泌胆汁的影响;采用测定小鼠胆囊重量的方法观察SMPS对胆囊的影响;对SMPS进行了小鼠急性毒性实验。

MethodsThe antipyretic activity of SMPS was observed in rats with high temperature induced by dried yeast and 2,4-dinitrophenol; biliary duct cannula bile at 0.5,1,1.5,2,2.5 h after intraduodenal administration in rats was collected and counted to observe the effect of SMPS on biliary secretion;the weight of cholecyst in mice was counted to observe the effect of SMPS on the cholecyst of mice;the acute toxicity test of SMPS was done with mice.

目的研究玉米须多糖的清热利胆作用及急性毒性。方法采用干酵母、2,4二硝基苯酚致大鼠发热的模型观察玉米须多糖的解热作用;采用胆管引流法分别收集并计量给药后0.5,1,1.5,2 ,2.5 h的胆汁的方法观察SMPS对肝脏分泌胆汁的影响;采用测定小鼠胆囊重量的方法观察SMPS对胆囊的影响;对SMPS进行了小鼠急性毒性实验。

MethodsThe antipyretic activity of SMPS was observed in rats with high temperature induced by dried yeast and 2,4-dinitrophenol; biliary duct cannula bile at 0.5,1,1.5,2,2.5 h after intraduodenal administration in rats was collected and counted to observe the effect of SMPS on biliary secretion;the weight of cholecyst in mice was counted to observe the effect of SMPS on the cholecyst of mice;the acute toxicity test of SMPS was done with mice.

方法采用干酵母、2,4二硝基苯酚致大鼠发热的模型观察玉米须多糖的解热作用;采用胆管引流法分别收集并计量给药后0.5,1,1.5,2 ,2.5 h的胆汁的方法观察SMPS对肝脏分泌胆汁的影响;采用测定小鼠胆囊重量的方法观察SMPS对胆囊的影响;对SMPS进行了小鼠急性毒性实验。

Lithogenous diet caused liver damage, then abnormality of metabolism of bile acids, and promoted gallstone formation.

致石食物首先引起肝脏病理损害,继而导致胆汁代谢紊乱,尤其是胆汁酸代谢紊乱,促使了胆结石的形成。

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