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The number of CD〓 and CD〓 lymphocytes subpopulation and IgA, IgM, IgG antibody-producing cells, the ratios of CD〓 and CD〓 T-cell in the cecal tonsils and Harderian glands, the content of IgA, IgM, IgG in tear, tracheal fluid, intestinal fluid and bile of CIAV-infected chicks vaccinated with ND vaccine were significantly decreased compared with vaccinated control chicks 7~28 days PV.

CIAV感染雏鸡ND免疫后28天内,哈德尔腺、盲肠扁桃体以及泪液、气管液、肠液、胆汁的上述各项免疫学指标,均不同程度的明显低于未感染CIAV的ND免疫雏鸡,表明CIAV感染雏鸡呼吸道和消化道局部粘膜对ND疫苗的细胞和体液免疫应答机能下降。

The number of CD〓 and CD〓 lymphocytes subpopulation, ANAE〓 T cells and IgG, IgM, IgA antibody-producing cells in the local immune tissues (cecal tonsils and Harderian glands), the content of IgA, lgM, IgG in the local fluid (tear, tracheal fluid, intestinal fluid and bile) of chicks infected with CIAV were significantly decreased compared with controls 7~28 days PI.

1日龄雏鸡感染CIAV后28天内,哈德尔腺和盲肠扁桃体的ANAE〓及CD〓、CD〓T细胞和IgA、IgM、IgG抗体生成细胞数量以及泪液、气管液、肠液、胆汁的IgA、IgM、IgG含量均明显低于对照雏鸡,表明CIAV感染雏鸡后,其呼吸道和消化道局部粘膜的细胞免疫和体液免疫机能均下降,这与CIAV感染雏鸡对其它某些病原易感性提高密切相关。

The dynamic changes of the number of T or B lymphocytes and the content of immunoglobulin G, IgM, IgA in peripheral blood, the number of CD〓, CD〓 lymphocyte subpopulation, T〓 cells and IgG, IgM, IgA antibody-producing cells, the ratios of CD〓 and CD〓 T cells in immune organs (thymus, bursa of Fabricius and spleen) and immune tissues (cecal tonsils and Harderian glands), the content of IgA, IgM, IgG in local fluid (tear, tracheal fluid, intestinal fluid and bile) of one-day chicks infected with chicken infectious anemia virus and CIAV-infected chicks immunized with Newcastle disease vaccine were determined respectively by immunohistochemistry, immunogold-silves and immunoenzyme staining in order to reveal mechanism of immunopathogenesis of chicks infected with CIAV and influence of immune responses of CIAV-infected chicks to ND vaccine.

中文题名雏鸡感染鸡传染性贫血病毒后免疫变化和对新城疫疫苗的应答及其免疫机理副题名外文题名 Immune changes of chicks infected with chicken infectious anemia virus and immune response and mechanism to Newcastle disease vaccine immunity 论文作者郑世民导师刘忠贵教授学科专业基础兽医学研究领域\研究方向学位级别博士学位授予单位东北农业大学学位授予日期2002 论文页码总数105页关键词鸡传染性贫血病雏鸡新城疫疫苗馆藏号BSLW /2003 /S858 /9 本项研究采用免疫组织化学、免疫胶体金及免疫酶方法,首次对CIAV感染1日龄雏鸡和CIAV感染雏鸡ND疫苗免疫及vNDV攻击后,其外周血液的T细胞、B细胞数量和IgG、IgM、IgA含量;中枢免疫器官胸腺和法氏囊,外周免疫器官脾脏及呼吸道和消化道局部粘膜免疫组织哈德尔腺和盲肠扁桃体的ANAE〓、CD4〓、CD〓T细胞、IgG、IgM、IgA抗体生成细胞数量和CD〓与CD〓T细胞比值以及泪液、气管液、肠液、胆汁的IgA、IgM、IgG含量的动态变化规律和CIAV感染对ND疫苗的免疫保护率等进行了全面系统地研究。

Methods: 83 cases of hepatolithiasis associated with biliary cirrhosis wereanalyzed retrospectively.

回顾性分析83 例肝胆管结石合并胆汁性肝硬化病例的诊断和治疗情况。

Results Hypercoagulability,low anticoagulatibility and activated fibrinogenolysis were seen in bile of patients with gallstones.

有文献报道人胆囊胆汁有纤溶活化因子和抑制因子的存在[1] 。

Results:Significant differences were found in strictured intervillous spaces of the placentae in ICP(P.05).Conclusion:Strictured intervillous space of the placentae in ICP is an important cause for acute hypoxia in the ute...

提示 :ICP胎盘绒毛间隙狭窄是围产儿宫内缺氧、病死率增加的重要原因,因此,重视预防和积极处理妊娠胆汁淤积症,改善胎盘功能,对降低围产儿死亡率,提高优生率有重要意义

In some concentration,bile reflux affect little on the intragastric pH.

在一定浓度下,胆汁反流对胃内pH值影响较小。

Objective: To discuss the incidence, diagnosis and management of intrahepatic cholestasis of pregnancy.

目的:探讨妊娠期肝内胆汁淤积症的发生率、诊断及处理。

Objective To study the clinical features and diagnosis of intrahepatic cholestasis of pregnancy.

目的 探讨妊娠肝内胆汁淤积症的发病规律和诊断。

Objective To investigate the correlation of hepatitis B virus infection and intrahepatic cholestasis of pregnancy.

目的 探讨乙型肝炎病毒感染与妊娠期肝内胆汁淤积症的相关性。

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