胆固醇

AIM: To establish an animal model of cholesterol stone and to explore the effects of cholecystokinin on gallbladder muscle stripes of guinea pigs with cholesterol stone in vitro as well as to investigate the role of biliary kinetics in cholesterol stone formation.

摘要目的：建立胆固醇结石实验动物模型，探讨胆囊收缩素(cholecystokinin， CCK)对胆固醇结石豚鼠离体胆囊肌条收缩的影响，并研究胆道动力因素在胆固醇结石形成中的作用。

As reported by some researchers, most of them enters the ER and is esterified by an ER enzyme ACAT2,then incorporated with apo B48 to produce de novo chylomicron which goes into the lymph and then to the circulation.

据文献报道，进入肠细胞的胆固醇能在酰基辅酶A：胆固醇酰基转移酶2(Acyl-Coenzyme A Cholesterol Acyltransferase，ACAT2)的作用下形成胆固醇酯，并与apoB48组装形成乳糜微粒，经淋巴进入血液。

In a double-blind trial, men with type 2 diabetes who took 5.1 grams of psyllium per day for eight weeks lowered their blood glucose levels by 11 to 19.2%, their total cholesterol by 8.9%, and their LDL cholesterol by 13%, compared with a placebo.

226在双盲试验中，2型糖尿病谁花了8个星期，每天5.1克，车前的男子降低了11血糖水平的19.2％，他们的总胆固醇8.9％，和低密度脂蛋白胆固醇胆固醇13 ％，比服用安慰剂。226

In the feedback regulation system of choles-terol metabolism, SCAP together with membrane-bound transcription factors - sterol regulatory element-binding proteins control transcription of the genes encoding enzymes of choles-terol and fatty acid biosynthesis.

在胆固醇代谢的反馈调节系统中，SCAP与膜结合转录因子胆固醇调节元件结合蛋白(sterol regulatory element binding proteins；SREBPs)等调节因子，共同控制一系列酶编码基因的转录过程，包括胆固醇和脂肪酸生物合成过程中所需的酶。

Determination of blood pressure and heart rate : At the end of 12 weeks after lercanidipine treated, the rabbits were anesthetized with Urethan (5ml/kg). The right carotid artery was cannulated with a te for the measurement of blood pressure.

血标本：在实验开始时和4周、8周、12周末分别测定血清总胆固醇、甘油三酯、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇，血清丙二醛含量和超氧化物歧化酶活力。

Acyl-CoA:cholesterol acyltransferase is the only enzyme of cholesteryl ester synthesis in cells,and plays an important role in balance between cells and organisms cholesterol metabolism.

酰基辅酶A：胆固醇酰基转移酶是细胞内惟一合成胆固醇酯的酶，在细胞和生物体胆固醇代谢平衡中起着重要作用。

We conclude that KB-R7843 has protective effects on contrast media-induced nephrotoxicity. The protective role of KB-R7943 may be related to its positive effects on renal hemadynamics through inhibiting the increase of ET-1 and TXA2 induced by contrast media in the environment of hypercholesterolemia and its cytoprotective influence on renal cells.

据此推导：（1）KB-R7943对高胆固醇血症环境下造影剂注射所致的肾损害有保护作用；（2）KB-R7943对造影剂肾损害的保护作用可能与其阻止高胆固醇血症环境下造影剂注射所致的肾皮质ET-1、TXA2浓度的上升从而阻止高胆固醇血症环境下注射造影剂所致的肾血流动力学的紊乱有关以及其对肾脏细胞的细胞保护作用有关。

Retrospectivly analyse the coronary heart disease, 68 patients diagnosed the coronary angiography, including Unstable Angina the 24 patients, Stable Angina 32 patients, myocardial infarction 12 patients; Compares the change of normal comparison group 35 patients fasting blood lipide:Trighycerides, Total Cholesterol, High Density Lipoprotein Cholesterol, Low Density Lipoprotein Cholesterol, Apolipoproteins (ApoA1 and ApoB), Fasting Blood Glucose, Fasting Insulin, Insulin area under curve and Glucose area under curve.

回顾性分析经冠状动脉造影确诊的冠心病患者68例，其中包括不稳定型心绞痛患者24例，稳定型心绞痛32例，心肌梗塞12例；正常对照组35例的空腹血脂（血清甘油三酯TG、血总胆固醇TC、高密度脂蛋白胆固醇HDL-C、低密度脂蛋白胆固醇LDL-C、载脂蛋白ApoA1及ApoB）、空腹血糖、空腹胰岛素、糖负荷后胰岛素曲线下面积及葡萄糖曲线下面积的变化并进行比较。

Objective To survey the relationship between nutrimental condition and the levels of serum lipids and lipoprotein. Methods The levels of total cholesterol, triglycerides high density lipoprotein cholesterol, low density lipoprotein cholesterol, apolipoprotein A1 (apoA1) and apolipoprotein B100(apo B100) B100 in 514 middle school students aged from 12 to 15 years old in Haikou City were determined.

目的 探讨营养状况与血脂及载脂蛋白水平的关系方法检测了海口市514例12～15岁中学生的营养状况并分析其与血清总胆固醇(Total-Cholesterol，TC)、甘油三酯(Triglycerides，TG)、高密度脂蛋白胆固醇(High Density Lipoprotein Cholesterol，HDL-C)、低密度脂蛋白胆固醇(Low Density Lipoprotein LDL-C)、载脂蛋白(Apolipoprotein，apo)A1及B100的关系。

Mensurated blood glucose, total cholesterol, low density lipoprotein, high density lipoprotein, triglyeride with venous blood drawed on an empty stomach. In addition, we measured ABI results of the same subject using Doppler and Oscillometric measurement.

抽取晨起空腹静脉血标本，应用标准方法测量如下血液指标：血糖、甘油三酯、总胆固醇、低密度脂蛋白胆固醇和高密度脂蛋白胆固醇。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。