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胆固醇

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Methods: Divide 196 cases into 3 groups by their blood pressure and cardiograph measure result. 62 cases in high blood pressure group, 45 cases in cardiovascular disease group, 89 cases in control group. HS-CRP and ABLU were measured by BN-Prospec Analysis System. GLU, TC. TG, HDL-C, LDL-C were measured by OLYMPUS 2700 Automatic biochemical analyzer.

对1%例70岁以上老年人通过血压和心电图结果分为三组,其中高血压62例;冠心病45例;对照组89例,空腹采血,留取晨尿,分别用BN-Prospec特种蛋白分析仪,测定尿微量白蛋白及超敏C反应蛋白,用OLYMPUS2700全自动生化分析仪测定空腹血糖、总胆固醇、甘油三酯、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇

Shown by GL-03 culture in vitro test, the ferment cultured milk has strong acid and cholate resistant ability, good adhesive, obvious inhibit to common pathogenic entero becteria, without drug tolerance factors, is a lactobacillus applicable to permanent planting of human body intestinal tract, and simultaneously the deterioration ratio of the cholesterol in vitro can be up to 56 percent; proved by the animal-test, the cholesterol-lowering cultured milk has the function of lowering serum cholesterol.

乳酸菌GL-03体外培养试验表明其有很强的耐酸、耐胆盐能力,粘附性好,对常见的肠道致病菌有明显的抑制作用,不携带耐药性因子,是一种适宜于人体肠道定植的乳酸菌,同时体外胆固醇降解率可达56%。动物试验证明降胆固醇酸乳具有降低血清胆固醇的功能。

Aim To study the effect of phosphalipids on the cholesterol efflux from rat macrophages mediated by HDL3. Methods Measure the cholesterol content, cellular phospholipid content, and the balance between free cholesterol and cholesteryl ester when phosphatidylcholine or sphingomyelin was added to the mediun.

为了研究卵磷脂和鞘磷脂对高密度脂蛋白3介导大鼠腹腔巨噬细胞内胆固醇流出的影响,测定了细胞内胆固醇含量、磷脂含量及游离胆固醇胆固醇酯平衡的变化。

ABSTRACT Aim To study the effect of phosphalipids on the cholesterol efflux from rat macrophages mediated by HDL3. Methods Measure the cholesterol content, cellular phospholipid content, and the balance between free cholesterol and cholesteryl ester when phosphatidylcholine or sphingomyelin was added to the mediun.

摘 要]为了研究卵磷脂和鞘磷脂对高密度脂蛋白3介导大鼠腹腔巨噬细胞内胆固醇流出的影响,测定了细胞内胆固醇含量、磷脂含量及游离胆固醇胆固醇酯平衡的变化。

The apoB gene polymorphism on Xba I site of 53 6 unrelated Chinese Han people,aged 25~64 years,was analyzed using PCR and Re striction Fragment Length Polymorphismmethod;serum apoA I,apoB,total chole s terol,triglyceride,HDL cholesterolwere measured,and LDL choleste roland non-HDL cholesterolwere calculated.

采用聚 合酶链反应结合限制性片段长度多态性分析的方法,分析536名25~64岁的无血缘关系的汉族人的apoB基因Xba I位点多态性,并测定其血清apoA I、apoB、总胆固醇、甘油三酯、高密度脂蛋白胆固醇,并计算低密度脂蛋白胆固醇LDL-C)及非高密度脂蛋白胆固醇

Methods Forty-five female rabbits were randomly divided into 5 groups, there are 9 in each: group A: normal control; group B: sham operation + cholesterol feeding; group C: OVX + cholesterol feeding; group D: OVX + cholesterol feeding + estradiol benzoate; group E: OVX + cholesterol feeding + estradiol valerate.

将45只3月龄雌兔随机分为5组,每组9只。A组为正常对照,B组为假手术+胆固醇饮食,C组为OVX+胆固醇饮食,D组为OVX+胆固醇饮食+苯甲酸雌二醇,E组为OVX+胆固醇饮食+戊酸雌二醇。

Hen THP-1 macrophages were induced to the foam cells by ox-LDL. Treatment of THP-1 macrophage derived foam cells with apoA-Ⅰ, forskolin (FRK, an adenyl cyclase activator), and SQ-22536 for long periods of time (24 h). In addition, THP-1 macrophage derived foam cells were treated with increasing amounts of FRK (0, 10, 20, 40 and 80 μmol/L) and treated with FRK for increasing time(0, 6, 12 and 24 h).

HP-1巨噬细胞源性泡沫细胞经各种因素处理后,采用油红&O&染色,观察细胞内的脂滴,运用液体闪烁计数器检测细胞内胆固醇流出,高效液相色谱分析细胞内总胆固醇、游离胆固醇胆固醇酯含量,用逆转录-聚合酶链反应和蛋白质印迹分析法分别检测ABCA1 mRNA与ABCA1蛋白质的水平。

OR>1 indicates dangerous factor, OR<1 protective factor, and OR=1 no significance. The results showed that if triglyceride and very low density lipoprotein cholesterol increased an average level of normal respectively, and there would be OR of TG 2.43 (P<0.05) and OR of VLDL-C 6.09 (P<0.05), the high levels of TG and VLDL-C were the factors of lithogenesis. High density lipoprotein cholesterols (HDL1-C, HDL2-C, HDL3-C), with OR less than one, were the factors of protecting against the formation of gallstone.

结果:甘油三酯和极低密度脂蛋白胆固醇每增加一个正常均值水平,OR值分别是2.43(P<0.05)和6.09(P<0.05),是重要的致石因素指标;高密度脂蛋白胆固醇(HDL1-C、HDL2-C、HDL3-C),OR值均低于1,是重要的防石因素指标;低密度脂蛋白胆固醇和总胆固醇的OR值均小于1,本研究结果提示其可能是一种代谢状态而非保护因素。

However,aortie fatty streaks were strongly related to ante一mortem levels of both total and low一density liPopro一tein eholesterol(:=0.67,p.0001 for eaeh assoei一ation),independently of raee,sex,and age,andwere inversely eorrel...

但主动脉脂肪条纹与死前总胆固醇及低密度脂蛋白胆固醇水平密切相关r=0.67,P(0.000一,二者同,与种族、性别、年龄无关,而与高密度脂蛋白胆固醇对低密度及极低密度脂蛋白胆固醇之比成负相关r二一。

This study demonstrates optically and spatially band-tunable color cone lasers based on DDCLC cells with a photoisomerizable chiral dopant. The band-tunability is attributable to the recovery of the helix of the CLC resulted from the trans-cis isomerization induced decrease of the helical twisting power of the chiral dopant.The more the chiral cis-isomers are produced, the larger the tuned lasing band is.

本文主要藉由在胆固醇液晶射中加入可光致同素构化亲手性材,使胆固醇液晶所输出的彩色锥角射波段可光调控及空间调控,其射输出波段可调控的机制是由於当同素构化反应产生后,光致同素构化亲手性材的HTP值低并造成胆固醇液晶距改变,藉此间接调控输出的射波长,同素构化的程愈高,胆固醇液晶所输出的彩色锥角射波段可调控范围也愈大。

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